Exercise Physiology Flashcards

1
Q

What are the immediate physiological responses to individual bouts of exercise?

A

Responses include increased heart rate, cardiac output, and local vasodilation.

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2
Q

What populations are discussed in relation to exercise physiology in this chapter?

A

Apparently healthy individuals and individuals with coronary artery disease.

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3
Q

What are the health benefits of physical activity in adults (18-64) and older adults (64+)?

A

Benefits include improved all-cause mortality, cardiovascular disease mortality, incident hypertension, incident type-2 diabetes, mental health, cognitive health, and sleep.

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4
Q

Fill in the blank: The WHO guidelines on physical activity provide evidence-based public health recommendations for _______.

A

[children, adolescents, adults, older adults]

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5
Q

True or False: The health benefits of physical activity are independent of the amount of activity performed.

A

False

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6
Q

What is the principle behind resistance training (RT) and aerobic exercise training (AET)?

A

The principle of progressive overload.

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7
Q

What is the typical resting heart rate range for an average individual?

A

60 to 80 beats per minute.

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8
Q

What happens to heart rate just prior to exercise?

A

Heart rate rises to above normal resting levels due to increased sympathetic activity.

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9
Q

What is the relationship between heart rate and exercise intensity?

A

Heart rate increases directly in relation to exercise intensity.

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10
Q

What adaptations occur in the cardiovascular system during sustained dynamic exercise?

A

Increased cardiac output and oxygen extraction in active skeletal muscle.

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11
Q

Fill in the blank: Cardiac rehabilitation specialists focus on motivating patients to develop a habitually _______ lifestyle.

A

[physically active]

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12
Q

What is the recommended exercise intensity for inducing a training effect?

A

Above a minimal level required to induce a training effect but below the intensity that evokes abnormal clinical signs.

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13
Q

What role does local vasodilation play during exercise?

A

It ensures sufficient blood supply to the working muscles.

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14
Q

What are the potential benefits of increasing physical activity levels within the general population?

A

Reduction in disease risk and improvement in health outcomes.

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15
Q

What is the importance of understanding the dose-response relationship in physical activity?

A

Some activity is better than none, but more activity generally confers greater benefits.

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16
Q

What are the specific outcomes improved by physical activity in older adults?

A

Prevention of falls, falls-related injuries, declines in bone health, and functional ability.

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17
Q

True or False: Sedentary behavior has no association with health outcomes.

A

False

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18
Q

What is the total blood flow at rest?

A

12,500 ml/min

This represents 73% of the total blood flow distribution.

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19
Q

What percentage of blood flow is directed to the brain at rest?

A

13%

This corresponds to 750 ml/min.

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20
Q

How much blood flow is allocated to the heart during strenuous exercise?

A

600 ml/min

This represents 3% of total blood flow during exercise.

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21
Q

What is the blood flow to the kidneys at rest?

A

1,100 ml/min

This accounts for 20% of blood flow.

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22
Q

During strenuous exercise, how much blood flow is directed to the muscles?

A

17,500 ml/min

This is the total blood flow to muscles during strenuous activity.

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23
Q

What percentage of blood flow is directed to the skin at rest?

A

10%

This corresponds to 600 ml/min.

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24
Q

Fill in the blank: The blood flow to the abdominal organs at rest is ______.

A

1,400 ml/min

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25
Q

What is the blood flow to the organs categorized as ‘Other’ at rest?

A

5800 ml/min

This is a significant portion of the total blood flow.

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26
Q

What is the blood flow to the heart during rest?

A

250 ml/min

This represents 4% of the blood flow.

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27
Q

What is the blood flow to the brain during strenuous exercise?

A

1,900 ml/min

This is an increase from the resting state.

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28
Q

What is maximal heart rate (HRmax)?

A

The highest heart rate value that is achieved in an all-out effort.

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29
Q

How does maximal heart rate change with age?

A

Maximal heart rate declines steadily with age by about 1 beat per year starting at 10-15 years of age.

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30
Q

What happens to heart rate during a submaximal workload held constant?

A

Heart rate usually achieves a steady state after an initial increase, plateauing at a constant workload.

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31
Q

How long is required to ensure steady state heart rate is achieved?

A

At least four minutes of constant workload.

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32
Q

What is cardiovascular drift?

A

The phenomenon where heart rate continues to drift upwards instead of maintaining a steady state during prolonged exercise, especially in hot conditions.

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33
Q

What happens to stroke volume during exercise?

A

Stroke volume initially increases with incremental workload but does not continue to increase beyond 40-50% of maximal capacity.

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34
Q

What factors contribute to the increase in stroke volume during exercise?

A
  • Increased contractility of the heart muscle due to increased sympathetic activity
  • Increased preload from greater volume of blood returned from the veins.
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35
Q

What happens to cardiac output as exercise intensity increases?

A

Cardiac output rises due to increases in heart rate and stroke volume.

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36
Q

What is the maximum increase in cardiac output during strenuous exercise for relatively sedentary men?

A

Cardiac output can increase as much as four-fold above resting level.

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37
Q

How does systolic blood pressure change during exercise?

A

Systolic blood pressure increases in direct proportion to increased exercise intensity.

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38
Q

What is a typical at-rest systolic blood pressure, and how can it change at maximal exertion?

A

A typical at-rest systolic blood pressure is 120 mm Hg and may exceed 200 mm Hg at maximal exertion.

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39
Q

How does diastolic blood pressure (DBP) respond to increased exercise intensity?

A

Diastolic blood pressure hardly changes at all as exercise intensity increases.

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40
Q

Fill in the blank: Maximal heart rate declines steadily with age by about _______ per year.

A

1 beat

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41
Q

What can the Valsalva manoeuvre induce during resistance training?

A

A large increase in venous return, leading to increased cardiac output and BP.

This can raise myocardial oxygen demand.

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42
Q

How can the Valsalva manoeuvre be avoided during exercise?

A

By exhaling during muscular contraction and inhaling during the eccentric phase.

This technique is recommended for proper breathing during resistance training.

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43
Q

What is the relationship between muscle mass and systolic blood pressure during exercise?

A

Systolic blood pressure will be greater when the exercising muscle mass is relatively small.

For example, arm exercises compared to leg exercises at the same absolute energy expenditure.

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44
Q

What happens to total peripheral resistance when a smaller muscle mass is used during exercise?

A

It is reduced less compared to exercises with larger muscle groups.

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45
Q

What is the rate pressure product (RPP) formula?

A

HR x SBP.

RPP is an indirect measure of myocardial oxygen consumption.

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46
Q

What type of work places greater stress on the myocardium for the same workload?

A

Static work or dynamic work restricted to the upper body.

Examples include pedaling with arms at 200 watts versus legs at 200 watts.

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47
Q

What percentage of cardiac output goes to skeletal muscle at rest versus during maximal exercise?

A

15-20% at rest; up to 80-85% during maximal exercise.

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48
Q

What does the sympathetic nervous system control during exercise?

A

Redistribution of blood from less active tissues to more active tissues, such as skeletal muscle.

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49
Q

What is the efficiency of the human machine during exercise?

A

About 20% efficient.

This means only 20% of energy expended is converted to external work.

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50
Q

What happens to blood flow during prolonged exercise in hot or humid conditions?

A

Blood is redirected to the skin for heat loss, reducing blood volume due to sweating.

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51
Q

What is the effect of reduced venous return on stroke volume during exercise?

A

Stroke volume is reduced, necessitating an increase in heart rate to maintain cardiac output.

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52
Q

What is the arterial venous oxygen difference [(a-v) O2 diff]?

A

The difference in oxygen content between arterioles and venules, representing oxygen extracted by tissues.

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53
Q

How much oxygen is typically present in blood at rest in arterioles and venules?

A

20 ml of oxygen per 100 ml in arterioles; 15 ml per 100 ml in venules.

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54
Q

How does the (a-v) O2 diff change during exercise?

A

It may increase approximately threefold between rest and maximal exercise levels.

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55
Q

What is the oxygen content in arteries at rest?

A

20 ml O2 per 100 ml blood

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56
Q

What is the oxygen content in veins at rest?

A

15-16 ml O2 per 100 ml blood

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57
Q

What is the oxygen content in veins during intense exercise?

A

5 ml O2 per 100 ml blood

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58
Q

What is the arterial mixed venous oxygen difference at rest?

A

4-5 ml O2 per 100 ml blood

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59
Q

What happens to plasma volume with the onset of exercise?

A

Immediate loss of blood plasma volume to the interstitial fluid space

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60
Q

What is the reduction in plasma volume during prolonged periods of exercise?

A

10% to 20%

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61
Q

What state is the myocardium in during rest?

A

Never really in a resting state

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62
Q

What is the oxygen extraction rate of the myocardium at rest?

A

Around 70%

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63
Q

What is the oxygen extraction rate of skeletal muscles at rest?

A

25%-30%

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64
Q

How does coronary blood flow change during exercise?

A

Increases more than threefold

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65
Q

What is the primary mechanism for coronary artery vasodilation during exercise?

A

Increased metabolic activity of the myocardium

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66
Q

Which substances contribute to vasodilation during exercise?

A

Adenosine, hydrogen ions, potassium ions, acetylcholine, blood lactate, and hypoxia

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67
Q

What role does the vascular endothelium play in vasodilation?

A

Produces and releases nitric oxide (NO) and prostacyclin

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68
Q

True or False: The sympathetic drive has a strong vasodilatory effect on coronary vessels.

A

False

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69
Q

What compensatory mechanism occurs in patients with left ventricular dysfunction during exercise?

A

Heart rate rises rapidly to compensate

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70
Q

What should be monitored in patients with heart disease during exercise?

A

Potential for ischaemic or arrhythmic episodes

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71
Q

Fill in the blank: The coronary arteries vasodilate due to the relaxation of ______.

A

smooth muscles in the coronary arterioles

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72
Q

What is the consequence of a challenge to the oxygen supply to the heart?

A

Impaired muscle function (ischaemia and possibly angina symptoms)

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73
Q

What is the effect of exercise on the heart’s oxygen extraction capacity?

A

Limited increase in extraction rates

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74
Q

What is the effect of damage to the endothelial lining on coronary artery vasodilation?

A

Coronary artery vasodilation is less responsive than in healthy arteries

This affects the warm-up period for exercise, making it more gradual and prolonged.

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75
Q

What happens to systolic blood pressure in patients with severe heart failure during exercise?

A

Systolic blood pressure may not rise and may even decrease

This is due to reduced cardiac output.

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76
Q

What is myocardial workload determined by?

A

The product of heart rate and systolic blood pressure

This is also referred to as the rate pressure product.

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77
Q

What should be done if a patient’s pre-exercise systolic blood pressure is higher than usual?

A

The training heart rate should be reduced for that particular session

This is important to offset any elevation in blood pressure.

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78
Q

What medications can blunt heart rate and blood pressure responses during exercise?

A

Beta-blockers and some calcium channel blockers

These medications are commonly prescribed for coronary heart disease patients.

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79
Q

What is the role of sympathetic stimulation during exercise?

A

It causes vasodilation of blood vessels supplying active tissues

This helps redistribute blood to active skeletal muscle.

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80
Q

What should patients avoid to guard against hypotensive episodes during exercise?

A

Abrupt changes in position and breath holding

Keeping feet moving helps ensure good venous return.

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81
Q

Why is fluid intake particularly important during exercise for individuals on diuretics?

A

Reduction in blood plasma volume occurs from the outset of exercise

This makes hydration critical for this population.

82
Q

What adaptations occur with regular exercise training?

A

Longer-term cardiovascular and metabolic adaptations

These include functional, structural, and biochemical changes.

83
Q

What does the effectiveness of exercise prescriptions depend on?

A

Manipulation of the FITT principle: frequency, intensity, time, and type of training

This is essential for tailoring exercise programs.

84
Q

What is the relationship between initial fitness and potential for change with exercise training?

A

The lower the initial fitness, the greater the potential for change

This applies to both men and women, young and old, with and without cardiac disease.

85
Q

What benefits do both Aerobic Exercise Training (AET) and Resistance Training (RT) offer?

A

Cardioprotective benefits

A combination of both is suggested for optimal results.

86
Q

What specific benefit does AET provide for people living with coronary heart disease?

A

Lowers resting heart rate

This brings additional anti-ischaemic benefits.

87
Q

What should exercise programming incorporate for patients with coronary heart disease?

A

RT following FITT principle guidelines and structured progressive AET

This combination is essential for effective management.

88
Q

What is the primary focus of the data presented?

A

Blood Pressure Response to Arm & Leg Work

89
Q

What are the two types of blood pressure measurements shown?

A

Systolic and Diastolic

90
Q

What does ‘L-Arm systolic’ refer to?

A

Systolic blood pressure measurement of the left arm

91
Q

What does ‘Leg systolic’ refer to?

A

Systolic blood pressure measurement of the leg

92
Q

What does ‘Arm diastolic’ refer to?

A

Diastolic blood pressure measurement of the arm

93
Q

What does ‘Leg diastolic’ refer to?

A

Diastolic blood pressure measurement of the leg

94
Q

What is the relationship between exercise intensity and blood pressure response?

A

Blood pressure increases with exercise intensity

95
Q

What physiological measurement is indicated on the x-axis of the graph?

A

Percentage of VO2 maximum

96
Q

Fill in the blank: Blood pressure is measured in _______.

97
Q

True or False: The graph displays both arm and leg blood pressure responses.

98
Q

What are the two types of training discussed in the document?

A

AET (aerobic training) and RT (resistance training)

AET focuses on improving cardiovascular fitness, while RT aims at increasing muscle strength and mass.

99
Q

What does VOzpeak stand for?

A

Peak oxygen uptake

VOzpeak is a measure of the maximum amount of oxygen the body can utilize during intense exercise.

100
Q

What are some whole-body adaptations to aerobic training?

A
  • Muscle strength
  • Muscle mass
  • Bone mineral density
  • VOzpeak
  • Physical function

These adaptations enhance overall physical performance and health.

101
Q

What is the effect of aerobic training on muscle strength?

A

Increasing effect

Aerobic training can improve muscle strength, although resistance training typically has a more significant impact.

102
Q

What health risk is associated with Type II diabetes?

A

Risk of poor glycaemic control

Poor glycaemic control can lead to various complications in individuals with Type II diabetes.

103
Q

How does resistance training affect bone mineral density?

A

Increasing effect

Resistance training is particularly beneficial for enhancing bone mineral density.

104
Q

What factors indicate cardiovascular disease risk?

A
  • Blood pressure
  • Blood lipids
  • High-density lipoprotein
  • Low-density lipoprotein
  • Cholesterol
  • Triglycerides

Monitoring these factors is crucial for assessing cardiovascular health.

105
Q

True or False: Aerobic training has a decreasing effect on insulin signaling.

A

False

Aerobic training typically improves insulin signaling, which is beneficial for metabolic health.

106
Q

Fill in the blank: The increasing effect of aerobic training on _______ can improve physical function.

A

VOzpeak

Enhancing VOzpeak contributes to better endurance and overall physical capability.

107
Q

What adaptation is NOT listed as a response to aerobic training?

A

Increased muscle mass

While aerobic training can improve muscle strength, resistance training is more effective for increasing muscle mass.

108
Q

What is the systolic pressure in mm Hg for arms at 50% of max VO2?

A

175

Systolic pressure values for arms at different percentages of max VO2 were recorded.

109
Q

What is the systolic pressure in mm Hg for legs at 75% of max VO2?

A

160

Systolic pressure values for legs at different percentages of max VO2 were recorded.

110
Q

What is the diastolic pressure in mm Hg for arms at 25% of max VO2?

A

90

Diastolic pressure values for arms at different percentages of max VO2 were recorded.

111
Q

What is the diastolic pressure in mm Hg for legs at 50% of max VO2?

A

73

Diastolic pressure values for legs at different percentages of max VO2 were recorded.

112
Q

True or False: The systolic pressure for arms increases as the % of max VO2 increases.

A

True

Systolic pressure for arms shows a clear upward trend with increasing % of max VO2.

113
Q

Fill in the blank: The diastolic pressure for legs at 75% of max VO2 is ______.

A

75

This value indicates how diastolic pressure behaves at high exercise intensities.

114
Q

What is the source of the data regarding intra-arterial blood pressure during exercise?

A

Astrand, P. O., et al.: Intra-arterial blood pressure during exercise with different muscle groups J. Appl. Physiol., 20:253 1965

This study provides the foundational data for understanding blood pressure responses during exercise.

115
Q

What does VOmax stand for?

A

Maximal oxygen uptake

116
Q

What type of exercise leads to greater increases in VOmax?

A

Aerobic exercise training (AET)

117
Q

What is the highest rate of oxygen consumption attainable during maximal or exhaustive exercise called?

118
Q

What percentage increase in VOmax can healthy individuals expect after 12 to 16 weeks of training?

A

10% to 25%

119
Q

What two factors determine maximal oxygen uptake?

A
  • Maximum cardiac output
  • Maximal ability of active skeletal muscle to extract and utilise oxygen
120
Q

What is the primary reason for increased maximal cardiac output due to training?

A

Increased maximal stroke volume

121
Q

What training-induced changes lead to an increase in left ventricular mass?

A
  • Increased chamber size
  • Increased total blood volume
  • Reduced total peripheral resistance
122
Q

What is a common characteristic of cardiac patients regarding training-induced changes?

A

Lack of evidence of training-induced increases in left ventricle mass and volume

123
Q

What are the peripheral changes that contribute to increased oxygen extraction and utilization?

A
  • Improved capillarisation
  • Increased myoglobin concentration
  • Increased number and size of mitochondria
  • Increased oxidative enzyme activity
124
Q

How does improved capillarisation affect muscle blood flow during maximal exercise?

A

It accommodates increased blood flow without shortening capillary transit time

125
Q

What type of adaptations are most relevant for cardiac patients?

A

Adaptations at submaximal levels of exercise

126
Q

What factors influence training adaptations in individuals with heart disease?

A
  • Severity of disease
  • Co-morbidity
  • Medication
  • Psychological status
  • Motivation
127
Q

What happens to heart rate at rest and during submaximal work after training?

A

It is lower after training

128
Q

What is the proposed mechanism behind the reduction in heart rate after training?

A

Increased parasympathetic activity and reduced sympathetic activity

129
Q

What is the effect of reduced circulating catecholamines on potential arrhythmias?

A

It lessens the potential for arrhythmias

130
Q

Fill in the blank: VOmax is determined centrally by maximum _______ and peripherally by the maximal ability of active skeletal muscle.

A

cardiac output

131
Q

True or False: Maximum heart rate changes with training.

132
Q

What happens to stroke volume at rest after training?

A

Stroke volume increases after training

This increase may result from greater filling of the left ventricle, a greater volume of blood entering the left ventricle, and increased ventricular mass.

133
Q

What are the factors contributing to increased stroke volume in trained individuals?

A
  • Greater filling of the left ventricle during diastole
  • Greater volume of blood entering the left ventricle
  • Increased ventricular mass
134
Q

How does cardiac output change after training at the same exercise intensity?

A

Cardiac output decreases after training

This is due to increased muscle oxygen extraction and improved oxygen usage economy of the skeletal muscle.

135
Q

What changes occur to blood pressure as a result of training?

A

Resting and submaximal blood pressures are reduced

The reduction may be as much as 10 mm Hg for SBP and 8 mm Hg for DBP.

136
Q

What is the Rate Pressure Product (RPP) and its implication in coronary artery disease?

A

RPP is reduced during submaximal exercise after training

This reduction benefits symptom control and quality of life for individuals with coronary artery disease.

137
Q

What is the effect of training on the ischaemic threshold for patients suffering from angina?

A

The ischaemic threshold is improved

This means patients can perform more work before experiencing angina symptoms.

138
Q

What occurs to muscle perfusion at rest following training?

A

Muscle perfusion at rest remains unaltered

However, at a given submaximal workload, blood redistribution to active muscle is reduced.

139
Q

What is the significance of improved oxygen extraction by active skeletal muscle after training?

A

More oxygen is extracted from each 100 millilitres of blood flowing through active skeletal muscle

The difference in oxygen content before and after training is greater.

140
Q

What happens to plasma volume after approximately 5 training sessions?

A

There is a significant increase in plasma volume

This enhances oxygen transport and temperature regulation.

141
Q

How does coronary blood flow improve as a result of training?

A

The reduction in heart rate leads to an extended period of diastole

This improves myocardial perfusion since blood flow to the left ventricle occurs during diastole.

142
Q

Fill in the blank: Following training, the reduction in heart rate and blood pressure at any specified workload allows for a delayed _______.

A

ischaemic threshold

143
Q

What effect does training have on blood pressure?

A

Blood pressure is reduced

Training is effective in lowering blood pressure as part of modifying CAD risk factors.

144
Q

How does training affect total cholesterol levels?

A

Total cholesterol is reduced; the effect is enhanced by concomitant weight/body fat reduction

A reduction in total cholesterol is more pronounced when combined with weight loss.

145
Q

What change occurs in high-density lipoprotein cholesterol due to training?

A

High-density lipoprotein cholesterol is increased

Increased HDL is beneficial for cardiovascular health.

146
Q

How does training influence glucose metabolism?

A

Glucose metabolism is improved with an increased sensitivity to insulin

Enhanced insulin sensitivity is crucial for managing blood sugar levels.

147
Q

What happens to fibrinolytic activity with training?

A

Fibrinolytic activity is increased with a reduction in platelet ‘stickiness’

Improved fibrinolytic activity helps in reducing clot formation.

148
Q

What is the impact of training on body fat?

A

Body fat is lost without loss of lean body mass, thereby preserving resting metabolic rate

Maintaining lean mass while losing fat is vital for metabolic health.

149
Q

List the benefits of resistance training (RT) on chronic disease.

A
  • Improved body composition
  • Improved blood lipid profile and vascular function
  • Improved blood pressure
  • Improved immune system function
  • Improved blood glucose and insulin sensitivity
  • Increased muscle mass and strength
  • Improved physical function and mobility
  • Greater oxidative capacity

These benefits highlight the role of RT in countering age-related chronic diseases.

150
Q

What is the increase in coronary blood flow during vigorous exercise?

A

4-6 times above resting levels

This increase is essential for meeting the heightened metabolic demands of the body during exercise.

151
Q

What are the three main mechanisms responsible for the increase in coronary blood flow during exercise?

A
  • Coronary arteries vasodilate
  • Increased metabolic activity through metabolic by-products
  • Endothelial vasodilators (e.g. nitric oxide)
  • Increased sympathetic activity (to a lesser degree)

These mechanisms work together to enhance blood flow to the heart muscle.

152
Q

What role do metabolic by-products play in coronary blood flow during exercise?

A

They stimulate vasodilation of coronary arteries

Increased metabolic activity during exercise leads to the accumulation of these by-products, which promote blood flow.

153
Q

True or False: Increased sympathetic activity is a primary mechanism for increased coronary blood flow during vigorous exercise.

A

False

Increased sympathetic activity plays a role, but it is to a lesser degree compared to other mechanisms.

154
Q

Fill in the blank: During vigorous exercise, coronary arteries _______ to increase blood flow.

A

vasodilate

This vasodilation is crucial for accommodating the increased demand for oxygen and nutrients by the heart.

155
Q

What is the primary endothelial vasodilator mentioned in the mechanisms of increased coronary blood flow?

A

Nitric oxide

Nitric oxide is a key factor in promoting vasodilation and enhancing blood flow during exercise.

156
Q

What are the acute responses of individuals with CHD compared to a healthy population?

A

Generally the same, but altered responses in specific areas.

157
Q

What happens to heart rate in individuals with impaired LV function?

A

Heart rate rises.

158
Q

What is the response of systolic blood pressure in individuals with impaired LV function?

A

Systolic blood pressure fails to rise.

159
Q

What condition affects the endothelial lining in individuals with CHD?

A

Damaged endothelial lining.

160
Q

Name two types of medication used for individuals with CHD.

A
  • Beta blockers
  • Ivabradine
  • Calcium channel blockers
161
Q

What is the effect of endurance training on submaximal heart rate?

A

Submaximal heart rate decreases with endurance training

This indicates improved cardiovascular efficiency.

162
Q

What does the graph depict regarding heart rate and speed?

A

The graph shows heart rate decreasing as speed increases post-training

Pre-training heart rates are higher at the same speeds.

163
Q

What is the range of heart rates depicted in the graph?

A

The heart rate ranges from 60 to 180 beats per minute

This range illustrates varying levels of exertion.

164
Q

Fill in the blank: The heart rate during submaximal exercise ______ after endurance training.

165
Q

True or False: Endurance training does not affect heart rate during submaximal exercise.

166
Q

What is the significance of a decrease in submaximal heart rate?

A

It indicates improved cardiovascular fitness and efficiency

A lower heart rate at the same workload suggests better heart function.

167
Q

What happens to coronary supply when heart rate is reduced for a given workload?

A

Coronary supply is increased due to increased diastolic filling time.

This is important for heart health as it allows more blood to flow to the heart muscle during relaxation.

168
Q

How does a reduced heart rate affect myocardial workload?

A

Myocardial workload is reduced, resulting in a lower rate-pressure product (RPP) for the same activity.

Lower RPP indicates less oxygen demand from the heart.

169
Q

What are the key benefits of a lowered heart rate for a given workload?

A

Key benefits include:
* Increased coronary supply
* Reduced myocardial workload

These benefits contribute to overall cardiovascular efficiency.

170
Q

What is the effect of aerobic endurance training on blood pressure?

A

Aerobic endurance training can lower both SBP and DBP by as much as 10 mmHg

SBP = Systolic Blood Pressure, DBP = Diastolic Blood Pressure

171
Q

How does a reduction in blood pressure affect myocardial workload?

A

If blood pressure is reduced, myocardial workload is also reduced, resulting in a lower RPP for the same activity

RPP = Rate Pressure Product, an indicator of myocardial oxygen demand

172
Q

What does SBP stand for?

A

Systolic Blood Pressure

173
Q

What does DBP stand for?

A

Diastolic Blood Pressure

174
Q

Fill in the blank: Aerobic endurance training can lower both _______ and _______ by as much as 10 mmHg.

A

[SBP], [DBP]

175
Q

True or False: Aerobic endurance training has no effect on myocardial workload.

176
Q

What is the significance of a lower RPP during activity?

A

It indicates reduced myocardial workload for the same level of activity

Lower RPP signifies that the heart is working less hard, which can be beneficial for cardiovascular health.

177
Q

What are the three types of blood vessels?

A

Artery, Capillary, Vein

178
Q

What is the normal oxygen content in blood?

A

20 ml O2 per 100 ml blood

179
Q

What is the a-vO2 difference in blood?

A

4-5 ml O2 per 100 ml blood

180
Q

What is the maximum oxygen content in blood?

A

15-16 ml O2 per 100 ml blood

181
Q

What changes occur in slow twitch fibers due to adaptations?

A

Increase in size and number

182
Q

What is improved in muscle adaptations?

A

Capillarisation

183
Q

What increases in muscle adaptations related to oxygen storage?

184
Q

What increases in number and size as a muscle adaptation?

A

Mitochondria

185
Q

What enzyme activity increases due to muscle adaptations?

A

Oxidative enzyme activity

186
Q

What is the effect of endurance training on VO₂ max?

A

Endurance training results in an increase in VO₂ max.

187
Q

What are the peripheral changes that affect VO₂ max?

A

Peripheral changes are determined by the maximal ability of active skeletal muscle to extract and utilize more oxygen.

188
Q

What are the central changes that affect VO₂ max?

A

Central changes are determined by maximum cardiac output.

189
Q

Why are central changes less relevant for CVD patients?

A

Central changes are less relevant for CVD patients.

190
Q

What is a key point regarding submaximal activity in CVD patients?

A

Submaximal activity will result in less physiological stress on the heart.

191
Q

What is the primary reason for the significant increase in maximum cardiac output?

A

An increased stroke volume rather than increased heart rate

This increase is attributed to several physiological changes.

192
Q

List the factors contributing to the increased stroke volume.

A
  • A training-induced increase in left ventricular mass and chamber size
  • An increase in total blood volume
  • A reduction in total peripheral resistance at maximal exercise

These factors enhance the heart’s efficiency during exercise.

193
Q

True or False: An increased heart rate is the main contributor to the increase in maximum cardiac output.

A

False

The increase in maximum cardiac output is primarily due to an increase in stroke volume.

194
Q

Fill in the blank: The significant increase in maximum cardiac output is primarily due to an increased _______.

A

[stroke volume]

195
Q

What does a training-induced increase in left ventricular mass and chamber size lead to?

A

Increased stroke volume

This adaptation allows the heart to pump more blood with each beat.

196
Q

What is the effect of exercise training on blood pressure?

A

Blood pressure is reduced

This is one of the key benefits of exercise training in modifying coronary heart disease (CHD) risk factors.

197
Q

How does exercise training affect total cholesterol levels?

A

Total cholesterol is reduced

Lowering total cholesterol is crucial in reducing the risk of coronary heart disease.

198
Q

What change occurs in high density lipoprotein (HDL) cholesterol due to exercise?

A

High density lipoprotein cholesterol is increased

Higher HDL levels are associated with a lower risk of heart disease.

199
Q

Fill in the blank: Exercise training improves glucose metabolism with an increased sensitivity to _______.

200
Q

What effect does exercise training have on fibrinolytic activity?

A

Fibrinolytic activity is increased with a reduction in platelet ‘stickiness’

This reduction helps in preventing blood clots, which can lead to heart attacks.

201
Q

What happens to body fat as a result of exercise training?

A

Body fat is lost without loss of lean body mass

Preserving lean body mass helps maintain a healthy resting metabolic rate.

202
Q

True or False: Exercise training can lead to a decrease in resting metabolic rate.

A

False

Exercise helps preserve resting metabolic rate by maintaining lean body mass.