Exercise and thrombosis

Question 1

What 2 things increase during exercise in metabolism?

Answer 1

liver glucose output
lipolysis & FFA mobilization

Question 2

What increases during exercise in skin?

Answer 2

sweat rate

Question 3

What 3 things increase during exercise in oxygen transport?

Answer 3

O2 uptake
HR
ventilation

Question 4

What 5 things increase during exercise in skeletal muscle?

Answer 4

ATP turnover
glycogenolysis
O2 utilization, CO2 & heat prod.
blood flow
release of ‘myokines’

Question 5

What type of exercise reduces mortality?

Answer 5

Habitual high intensity exercise

Question 6

What plasma proteins have been seen to show up after acute exercise?

Answer 6

cytokines
red cell/myocyte/platelet/neutrophil proteins
clotting factors

Question 7

What 3 proteomic changes were shown after training-induced adaptation?

Answer 7

Proteins involved with:
Angiogenesis
ECM
Iron homeostasis

Question 8

What does acute exercise have an immediate effect on?

Answer 8

Platelet function & clotting (increased risk for CV after high intensity)

Question 9

What is chronic fitness associated with?

Answer 9

Reduced levels of platelet function & clotting

Question 10

What does both acute and chronic exercise activate?

Answer 10

Fibrinolysis

Question 11

Is the effect of exercise on endothelial function good or bad?

Answer 11

Good

Question 12

What 2 things does increased muscle blood flow during exercise lead to?

Answer 12

Increased shear stress
increased release of endothelial vasodilators

Question 13

What 2 things does exercise increase in patients with coronary artery disease?

Answer 13

Arterial blood flow
eNOS expression