Exercise And The Skeleton Flashcards
What do bones do
They protect vital organs
They allow muscles to work to move us
They store minerals and marrow cells
They shape and provide structure for the body
What is wolfs law
Every change in the form and function of bone or of their function alone is followed by certain definite changes in their internal architecture, and equally definite alteration in their external conformation, in accordance with mathematical laws.
What is the utah paradigm
Healthy, postnatal load-bearing bones are designed to have only enough strength to keep chronically subnormal, normal or supernormal voluntary loads (not injuries) from causing spontaneous fractures.
What happens to bones when they are loaded
Deformation and strain
What is the mechanostat theory
Bone growth and bone loss is stimulated by the local, mechanical, elastic deformation of bone
Which cells are responsible for sensing loading/disuse
Osteoblasts
Osteocytes
How does the osteocyte sense loading
Hydrostatic pressure
Direct cellular deformation
Fluid flow shear stress
What is the dominant influence on bone strength
Loading
What happens when you exercise
Bone is formed
What cells of the bone are the main mechanosensor and mechanotransducers
Osteocytes
What are the key processes in adaptive changes in bone
Fluid flow shear stress
Intracellular communications
