EXAM III Last of Pulmonary Flashcards
What factors allow the diffusion capacity of oxygen to increase during exercise?
Increased surface area of capillaries participating in diffusion
An ideal V/Q ratio in upper parts of the lungs
What factors determine tissue PO2?
Rate of oxygen transport to the tissues
Rate of oxygen consumption by the tissues
Define oxygen utilization coefficient; how is it calculated?
Percentage of blood that gives up its oxygen
During _____(high or low) PO2, oxygen is bound to Hb (pulmonary capillaries)
During ____(high or low) PO2, oxygen is released from Hb (tissue capillaries)
High
Low
What are the 4 factors that shift the oxygen-Hb dissociation curve to the right?
BPG
Increased CO2
Increased [H+]
Increased temperature
What is the Bohr effect and what effect does it have on the O2-dissociation curve?
When there is a decreased amount of O2 associated with the Hb and other respiratory compounds in response to a lowered blood pH resulting from an increase in blood [CO2]
Right-shift curve, release of O2
What are the 3 ways CO2 is transported in the blood? What are the approx percentages of CO2 that is transported by each mechanism?
Carbonic acid = 70%
Dissolved in blood = 7%
Carbamino Hb = 23%
What are the 5 respiratory centers? Where are they located and what are their functions?
D.P.PreB.B.
DRG - tractus solitarius - NTS (nucleus of tractus solitarius) and medulla reticular substance
VRG
PRG (pons) = Apneustic Center and Pneumotaxic Center
Pre-Botzinger complex
Botzinger complex
Which respiratory center establishes the ramp signal?
Dorsal Respiratory Group