EXAM III Clicker Qs Flashcards

1
Q
The thin descending LOH is highly permeable to which of the following:
Sodium
Water
Urea
Amino Acids
A

Water

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2
Q
Aldosterone is an important regulator of Na+ reabsorption and K+ secretion; one of its main targets is...?
Podocyte
Principal Cells
Intercalated Cells
Cells of Macula Densa
A

Principal cells

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3
Q
The macula densa is found in which of the following parts of the renal tubule?
PCT
Thin descending limb of Henle
Thick ascending limb of Henle
DCT
A

DCT

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4
Q
Which of the following would be a result of increased levels of angiotensin II?
Decreased BP
Increased vasoconstriction
Increased natriuresis
Decreased aldosterone levels
A

Increased vasoconstriction

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5
Q
Which of the following in liters/day represents the GFR in the average adult human?
3
125
180
360
A

180

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6
Q
An increase in which of the following factors will result in decrease in glomerular hydrostatic pressure?
Arterial pressure
Afferent arteriolar resistance
Efferent arteriolar resistance
Both B and C
All of the above
A

Afferent arteriolar resistance

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7
Q

Almost 90% of glucose reabsorption occurs in the early PCT. Which of the following mechanisms is responsible for moving glucose from the tubular lumen into the cytoplasmic compartment?
Primary active transport via a glucose ATPase pump
Secondary active transport via a Na+/glucose cotransporter
Secondary active transport via a Na+/glucose antiporter
Diffusion due to [ ] differences b/w tubular fluid and cytoplasm

A

Secondary active transport via a Na+/glucose cotransporter

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8
Q
Which hormone's sources is the posterior pituitary?
Aldosterone
Angiotensin II
ADH
ANP
A

ADH

Made in the hypothalamus, secreted in posterior pituitary

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9
Q

Which of the following describes a valid change in K+ distribution due to an acid-base abnormality?
Metabolic acidosis decreases extracellular [K+]
Metabolic alkalosis increases extracellular [K+]
Metabolic acidosis increases extracellular [K+]
Both A and B are valid

A

Metabolic acidosis increases extracellular [K+]

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10
Q

A high K+ intake would have which of the following effects on K+ excretion associated with increased renal tubular flow rate?
K+ excretion would increase with increased tubular flow rate
K+ excretion would decrease with increased tubular flow rate
There would be little effect
Tubular flow rate would be decreased

A

K+ excretion would increase with increase tubular flow rate

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11
Q
Most K+ reabsorption occurs at which of the following sites?
Ascending LOH
DCT
PCT
Collecting duct
A

PCT

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12
Q
Which of the following cells play a major role in the secretion of K+?
Intercalated cells
Principal cells
Chief cells
Podocytes
A

Principal cells

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13
Q
Approx how much of the body's supply of Ca2+ is stored in the bone?
1%
47%
78%
99%
A

99%

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14
Q
How much of filtered Ca2+ is reabsorbed by the kidneys?
1%
45%
78%
99%
A

1%

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15
Q
Which of the following cells reabsorb K+ during depletion?
Intercalated cells
Principal cells
Chief cells
Podocytes
A

Intercalated cells

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16
Q
Which of the following buffer systems is most important in buffering renal tubular fluid?
Phosphate buffer system
Carbonate buffer system
Bicarbonate buffer system
Hb buffer system
A

Phosphate buffer system

Due to phosphates being concentrated in the renal tubular fluid

17
Q
Compounds that dissociate incompletely into H+ ions and a conjugate base are members of which of the following compounds?
Strong acids
Weak acids
Strong bases
Weak bases
A

Weak acid

18
Q
The bicarbonate buffer system consists of a bicarbonate salt and which of the following?
Weak acid
Strong acid
Strong bases
Weak bases
A

Weak acids

19
Q

Primary active H+ secretion involves a H-transporting ATPase. It occurs in which of the following parts of the renal tubules?
Descending limb of Henle

Ascending limb of Henle

Late distal tubule in intercalated cells

Early collecting tubules in principal cells

A

Late distal tubules in intercalated cells

20
Q

Most bicarbonate reabsorption occurs in which of the following parts of the renal tubule?

Proximal tubule

Descending limb of Henle

Ascending limb of Henle

Distal tubule

A

Proximal tubule

21
Q

Which of the following occurs when a decrease in bicarbonate ion results in a decrease in the ratio of bicarbonate ion to CO2 in the extracellular fluid?

Respiratory acidosis

Respiratory alkalosis

Metabolic acidosis

Metabolic alkalosis

A

Metabolic acidosis

22
Q

Respiratory alkalosis due to a decrease in [CO2] caused by hyperventilation is compensated for by which of the following mechanisms?

Increased ventilation rate

Decreased ventilation rate

Renal excretion of bicarbonate ion

Renal addition of new bicarbonate ion to extracellular fluid

A

Renal excretion of bicarbonate ion

23
Q

The lung apices (apex) have which zone flow?

Zone 1

Zone 2

Zone 3

A

Zone 2; lower areas have zone 3 flow

In standing position, more blood flows to the base/bottom of lungs

24
Q

The base of the lungs have which zone flow?

Zone 1

Zone 2

Zone 3

A

Zone 3; while standing, as much as 5x more blood flows to the base of the lungs rather than the apex

25
Q

Acidosis occurs when the ratio of bicarbonate ion to CO2 is the extracellular fluid decreases. When this change is due to a decreases in bicarbonate ion, it is called respiratory acidosis (bicarbonate = metabolic)

True
False

A

False

26
Q
The volume by which the lungs and thorax increase for each unit of pressure change in the transpulmonary pressure is referred to as:
Tidal volume
Inspiratory pressure
Compliance
Transpulmonary volume
Elasticity
A

Compliance

27
Q

During heavy exercise blood flow through the lungs increases 4 to 7x that at rest. This increase is due to which of the following:
Increase in the number of open capillaries up to 3x normal
Distension of capillaries and a doubling in the flow rate
Increase in pulmonary arterial pressure
All the above
A and B only

A

All the above

28
Q
The Va/Q ratio is 0 under which of the following conditions?
Va = infinity, but Q = 1
Va = infinity, but Q = 0
Va = 0, but perfusion >0
Va > 0, but Q = 0
A

Va = 0, but perfusion > 0

29
Q

According to the O2 Hb dissociation curve, an increase in blood partial oxygen pressure will have which of the following effects?
A decrease in bound O2
An increase in bound O2
No change in blood O2
There is no correlation b/w the 2 variables

A

An increase in bound O2

30
Q

Reduction of blood flow to a portion of the lung has which of the following effects? ( constriction - less gas exchange happening)
Alveolar pCO2 is lowered, resulting in a constriction of the bronchi supplying that portion of the lung
Alveolar pCO2 is elevated, resulting in a constriction on the bronchi supplying that portion of the lung
Alveolar pCO2 is lowered, resulting in a dilation of the bronchi supplying that portion of the lung
Alveolar pCO2 is elevated, resulting in a constriction of the bronchi supplying that portion of the lung

A

Alveolar pCO2 is lowered, resulting in a constriction of the bronchi supplying that portion of the lung

31
Q

One gram of Hb can bind to how much oxygen?

  1. 4 ml O2
  2. 4 ml O2
  3. 25 ml O2
  4. 34 ml O2
A

1.34 ml O2