Exam - Chapter 9 Flashcards
an increase in muscle mass and cross-sectional area; increase in dimension is due to an increase in the size (not length) of individual muscle fibers
muscle hypertrophy
Factors involved in muscle hypertrophy
satellite cells, immune system, growth factors, growth hormone, testosterone, muscle fiber types
fuse to the existing muscle fiber, donating their nuclei to the fiber, which helps to regenerate the muscle fiber
satellite cells
a peptide hormone that stimulates IGF (insulin-like growth factor) in skeletal muscle, promoting satellite cell activation, proliferation, and differentiation
growth hormone
produced in significantly greater amounts in males, has an anabolic (muscle building) effect; increases protein synthesis, which induces hypertrophy
testosterone
structures containing the contractile proteins actin and myosin
thick and thin filaments
overlapping parallel groups of thick and thin filaments in a repeating pattern; the underlying basis for the striation pattern
myofibril
a single muscle cell, multinucleate and may be many centimeters long
muscle fiber
a bundle of muscle fibers within a muscle; covers each skeletal muscle; alters of dense connective tissue
fascicle
a bundle of fascicles
muscle
the connective tissue associated with a muscle that forms these broad fibrous sheets; may be attached to bone or the coverings of adjacent muscles
aponeuroses
the layer of connective tissue that closely surrounds a skeletal muscle
epimysium
another layer of connective tissue that extends inward from the epimysium and separates the muscle tissue into small sections called fascicles
perimysium
a thin covering that surrounds the muscle fiber within a fascicle
endomysium
muscle cell membrane
sarcolemma
muscle cytoplasm; contains mitochondria, sarcoplasmic reticulum, myofibrils, and actin and myosin
sarcoplasm
thick filaments composed of protein
myosin
thin filaments composed of primarily this protein
actin
the functional unit of a muscle; the relating units of striations (myosin and actin)
sarcomere
rod-shaped protein; occupies the longitudinal grooves of actin helix, held in place by troponin
tropomyosin
a set of membranous channels that extend from the cell membrane into the cytoplasm; has two cisternae on each side
transverse (T) tubules
an electrical impulse that is sent down axons of neurons
action potential!
the functional connection between a neuron and another cell; the neuromuscular juntion
synapse
chemical is released after neurons communicate with the cells they control
neurotransmitters
neurons that control effectors; stimulate muscle fibers to contract
motor neurons
the muscle fiber membrane forms this!; where nuclei and mitochondria are abundant and a sarcolemma is extensively folded
motor end plate
order of muscle dimension: largest to smallest
muscle, fascicles, muscle fibers (cells), myofibrils, thick and thin filaments
a small gap that separates the membrane of the neuron and the membrane of the muscle finer; where electricity comes down an axon and neurotransmitters are transferred
synaptic cleft
the neurotransmitter that motor neurons use to control skeletal muscle conrtraction
acetylcholine
synthesized in the cytoplasm of the motor neuron and is stored in the synaptic vesicles at the distal end of its axon; released into the synaptic cleft when action potential occurs
acetylcholine again!
Sodium ion concentration is higher ____ the cell and potassium ____ the cell
outside/inside
happens in response to stimulation of the sarcoplasmic reticulum and releases calcium ions; binds to troponin and causes tropomyosin to shift and expose active sites on the actin for myosin binding
excitation-concentration coupling
when the overlapping thick and thin myofilaments slide past one another, the sarcomere shortens and the muscle contracts
sliding filament theory
a myosin head can attach to an actin binding site to form a cross bridge which pulls on the actin filament
crossbridge cycling
occurs when a muscle contracts (equal force, change in length)
isotonic contraction
rapidly decomposes acetylcholine remaining in the synapse, which prevents continuous stimulation of a muscle fiber
acetylcholinesterase
The energy sources of muscle contraction
ATP, phosphocreatine, anaerobic (glycolysis), aerobic (oxidative phosphorylation)
synthesized in muscle cells; temporarily stores some oxygen
myoglobin
contraction where muscle shortens; force is greater than resistance and shortens
concentric contraction
muscle lengthens; contracts with face less than resistance
eccentric contraction
muscle contracts but does not change length (holding body upright)
isometric contraction
stored glucose
glycogen
C6H10O5
glycogen
C6H12O6
Glucose
consists of one motor neuron and the muscle fibers associated with it
motor unit
Will many motor units be needed for finer muscle movements?
Nope! fewer=finer
a type of muscle fiber; always oxidative and resistant to fatigue; red fibers (contain myoglobin); rely on oxygen to function
slow twitch (type 1)