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PHA 415 - Therapeutics III > Exam 5 - Infectious Disease Pathophysiology > Flashcards

Exam 5 - Infectious Disease Pathophysiology Flashcards

1
Q

T/F: Meropenem does not cover MRSA, enterococcus, or fungus.

A

TRUE

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2
Q

What are the four types of BETA-LACTAMS?

A

1) PCN
2) Cephalosporins
3) Carbapanems
4) Monobactam

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3
Q

The four types of beta-lactams include: ____, _____, _____, and _____.

A

The four types of beta-lactams include: PENICILLINS, CEPHALOSPORINS, CARBAPENEMS, and MONOBACTAM.

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4
Q

Name the four penicillin drugs.

A

1) PCN G
2) PCN VK
3) Procaine PCN
4) Benzathine PCN

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5
Q

Name the three penicillin-ase resistant penicillins.

A

1) Nafcillin
2) Oxacillin
3) Dicloxacillin

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6
Q

Name the 4 amino penicillins.

A

1) Ampicillin
2) Amoxicillin
3) Ampicillin-sulbactam = UNASYN
4) Amoxicillin-clavulanic acid = AUGMENTIN

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7
Q

What is the generic name for Unasyn?

A

Amoxicillin-sulbactam

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8
Q

What is the brand name for Amoxicillin-sulbactam?

A

Unasyn

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9
Q

What is the generic name for Augmentin?

A

Amoxicillin-clavulanic acid

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10
Q

What is the brand name for Amoxicillin-clavulanic acid?

A

Augmentin

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11
Q

Name the extended spectrum PCN.

A

Piperacillin-tazobactam = ZOSYN

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12
Q

How is Piperacillin-tazobactam classified?

A

It is an extended-spectrum pcn

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13
Q

What is the generic name for Zosyn?

A

Piperacillin-tazobactam

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14
Q

What is the brand name for Piperacillin-tazobactam?

A

Zosyn

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15
Q

Name the two Oxazolidinone drugs.

A

1) Linezolid = Zyvox

2) Tedazolid = Sivextro

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16
Q

How are Linezolid and Tedazolid classified?

A

They are both Oxazolidinone drugs

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17
Q

What is the brand name for Linezolid?

A

Zyvox

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18
Q

What is the brand name for Tedazolid?

A

Sivextro

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19
Q

What is the generic name for Sivextro?

A

Tedazolid

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20
Q

What is the generic name for Zyvox?

A

Linezolid

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21
Q

When are the penicillin-ase resistant penicillins used?

A

For MSSA

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22
Q

What are the penicillin-ase resistant penicillin drugs that are used for MSSA?

A

Nafcillin
Oxacillin
Dicloxacillin

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23
Q

Why are penicillin drugs used so often?

A

They are narrow spectrum drugs

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24
Q

What are the uses for Benzathine and Procaine?

A 
Syphillis
Strep throat (IM injection)
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25
Name the classes of drugs that fall under Beta-Lactam drugs.
- PCN - Cephalosporins - Carabapenems - Monobactam
26
What do Unasyn (Ampicillin-sulbactam), Augmentin (Amoxicillin-clavulanic acid), and Zosyn (Piperacillin-tazobactam) have in common?
They have beta-lactamase inhibitors with them
27
Name the two 1st generation cephalosporins.
1) Cefazolin (Ancef) | 2) Cephalexin (Keflex)
28
How are Cefazolin and Cephalexin classified?
1st generation cephalosporin
29
What is the brand name for Cefazolin?
Ancef
30
What is the generic name for Ancef?
Cefazolin
31
What class of drug is Cefazolin (Ancef)?
1st generation cephalosporin
32
What is the generic name for Keflex?
Cephalexin
33
What is the brand name for Cephalexin?
Keflex
34
What class of drugs are Ancef and Keflex?
1st generation cephalosporins
35
Name the five 2nd generation cephalosporins.
1) Cefuroxime = Ceftin 2) Cefoxitin = Mefoxitin 3) Cefotetan 4) Cefaclor = Ceclor 5) Cefprozil = Cefzil
36
What is the generic name for Ceftin?
Cefuroxime
37
What is the generic name for Mefoxitin?
Cefoxitin
38
What is the generic name for Ceclor?
Cefaclor
39
What is the generic name for Cefzil?
Cefprozil
40
What is the brand name for Cefprozil?
Cefzil
41
What is the generic name for Ceclor?
Cefaclor
42
What is the generic name for Mefoxitin?
Cefoxitin
43
What is the generic name for Ceftin?
Cefuroxime
44
What are the 2nd generation cephalosporins?
Cef x 5 (Cef-o x 2, Cef-a, Cef-p, Cef-u) 1) Cefuroxime 2) Cefoxitin 3) Cefotetan 4) Cefaclor 5) Cefprozil
45
What class of drug is Cefepime (Maxipime)?
4th generation cephalosporin
46
What class of drug is Ceftaroline (Teflaro)?
5th generation cephalosporin
47
What class of drug is Clindamycin (Cleocin)?
Lincomycin
48
Name the ten 3rd generation cephalosporins.
1) Ceftriaxone = Rocephin 2) Cefotaxime = Claforan 3) Ceftazidime = Fortax 4) Ceftazidime-avibactam = Avycaz 5) Cefpodoxime = Vantin 6) Ceftibuten = Cedax 7) Cefixime = Suprax 8) Cefditoren = Spectracef 9) Cefdinir = Omnicef 10) Ceftolozane-tazobactam = Zerbaxa
49
What is the generic of the following 3rd gen cephalosporin: Rocephin?
Ceftriaxone
50
What is the generic of the following 3rd gen ceph: Claforan?
Cefotaxime
51
What is the generic of the following 3rd gen ceph: Fortax?
Ceftazidime
52
What is the generic of Rocephin?
Ceftriaxone
53
Name the 1st gen ceph drugs (FA, PHA).
1) Cefazolin (Ancef) | 2) Cephalexin (Keflex)
54
Name the 2nd Gen Ceph drugs (1 ME, TIN, TAN, CLOR, ZIL).
1) Cefuroxime 2) Cefoxitin 3) Cefotetan 4) Cefaclor 5) Cefprozil
55
What type of Gram stain are Staphylococci, Coagulase-negative staphylococcus, and streptococcus?
Gram POSITIVE
56
What type of Gram stain is E. coli?
Gram NEGATIVE
57
What type of Gram stain is Klebseilla, Enterobacter, and Citrobacter spp.?
Gram NEGATIVE
58
Zosyn, Cefepime, and Meropenem all cover what type of bacteria (+ or -)?
Gram NEGATIVE
59
What does mecA convert?
MSSA into MRSA
60
What does mecA do?
Converts MSSA into MRSA
61
A mecA positive organism is what type of organism?
MRSA
62
T/F: Not all carbapenems cover pseudomonas.
TRUE | - Ertapenem does not cover pseudomonas
63
_____ makes enterococcus vancomycin-resistant enterococci (VRE).
vanA makes enterococcus vancomycin-resistant enterococci (VRE).
64
____ makes E. coli, K. pneumoniae, Proteus spp. resistant to 3rd gen CPN.
ESBL makes E. coli, K. pneumoiae, Proteus spp. resistant to 3rd gen CPN.
65
What is the drug of choice for ESBL?
Carbapenems - Ertapenem since you do not need pseudomonas coverage
66
Brand name of Ertapenem = ?
Invanz
67
____ makes K. pneumoniae resistant to carbapenems (Carbapenemase).
KPC makes K. pneumoniae resistant to carbapenems (Carbapenemase).
68
What is the drug of choice for KPC?
Ceftazidime/Avibactam | Cefiderocol
69
Drug of choice for MSSA?
Nafcillin Oxacillin Cefazolin
70
Drug of choice for Rocky Mountain Spotted Fever?
Doxycycline
71
Drug of choice for B. fragilis?
Metronidazole - for ANAEROBES
72
What do you give in a pregnant patient with Group B strep?
PCN G

PHA 415 - Therapeutics III (17 decks)

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