Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Therapeutics III > Exam 5 (final) - Ott BPD > Flashcards

Exam 5 (final) - Ott BPD Flashcards

1
Q

6 drugs for mood stabilization in BPD

A

lithium (best)
valproic acid
carbamazepine
oxcarbazepine
lamotrigine
topiramate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

secondary options for BPD

A

antipsychotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

lithium in pregnancy recommendations

A

avoid in 1st trimester
-caution in 2nd and 3rd

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

lithium teratogen effect

A

cardiac structural abnormality (Ebstein’s)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

lab monitoring for lithium

A

SCr, BUN
electrolytes (Na, K, Ca)
thyroid fxn
CBC
weight
pregnancy test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

drug interactions that cause increased levels of lithium

A

ACEis
ARBs
thiazides
NSAIDs
dehydration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

drug interactions that cause decreased levels of lithium

A

caffeine
osmotic diuretics
loop diuretics
NaHCO3
high Na intake

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

target serum levels for lithium

A

acute tx: 0.9-1.2 mEq/L
maintenance: 0.6-0.9 mEq/L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

when to draw trough serum concentrations for lithium

A

72 hours after initiation, 12 hours after last dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

target serum levels for valproate

A

80-125 mcg/mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

when to draw trough serum concentrations for valproate

A

96 hours (4 days) after first dose or a dose increase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

valproate in pregnancy recommendations

A

not safe in pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

valproate teratogen effect

A

neural tube defect
decreased IQ in offspring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

valproate AE

A

PCOS (50% of women)
weight gain (~6-8kg)
GI
-NVD
-ulcers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

lab monitoring for valproate

A

pregnancy test
LFTs
CBC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

valproate drug interactions

A

lamotrigine
-when used in combo with this, it increases levels of lamotrigine which can lead to SJS

17
Q

carbamazepine and oxcarbazepine are ______ line drugs

A

2nd or 3rd

18
Q

oxcarbazepine associated with ______

A

hyponatremia

19
Q

carbamazepine associated with _________

A

thrombocytopenia

20
Q

lamotrigine is useful in _____ pole of bipolar disorder

A

depressive

21
Q

T/F: lamotrigine is useful in acute episodes of mania in bipolar depression

A

F

Therapeutics III (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions