Exam 4- RNA viruses Flashcards
What are the type of proteins on the envelope of retroviridae?
gag
3 important viral enzymes in retroviridae?
1) Reverse transcriptase
2) Integrase
3) RNA polymerase II (RNAPII)
_________ - any virus with DNA or RNA genome causing cancer
Oncovirus
________- gene that encodes for proteins regulating gell growth and differentiation and that can become an oncogene.
Proto-oncogene
________- are required for building in the genetic material.
Active cells
2 types of mechaisms of transformation for Retroviruses?
- Proto-oncogenes mistakenly incorporated into provirus
- Disruption of cellular proto-oncogenes
What is the genus and species of this disease?
Also the disease’s common name?
Alpharetrovirus
Avian sarcoma leucosis virus (ASLV or ALV)
AKA- Avian Leukosis
________– causes lymphoid leucosis and lymphoma (blood cell tumor from lymphocytes
Avian Leukosis
The genus and species of Enzootic Nasal Tumor?
G-Betaretrovirus
S-Enzootic nasal tumor virus (ENTV)
What is the host for Enzootic Nasal Tumor?
sheep,goats
The genus and species for Jaagsiekte?
G-Betaretrovirus
S- Jaagsiekte sheep retrovirus (JSRV)
_________– is a contagious lung cancer or ovine pulomonary adenocarcinoma.
Jaagsiekte
Clinical signs of Jaagsiekta?
Respiratory distress when you chase the animal, Lots of nasal discharge.
What is the genus and species? and common name?
G- Deltaretrovirus
S- Bovine Leukemia virus (BLV)
AKA- Bovine Leukosis
Symptoms of Bovine Leukosis?
-enlargement of lymph nodes
Ex: retro-ocular –> protrusion of conjunctional membrane
What is the genus and species of Feline Leukemia?
G- Gammaretrovirus
S- Feline Leukemie virus (FeLV)
What is diseas? its Genus, species also?
Equine Infectious Anemia aka swamp fever
G- Lentivirus
S-Equine infectious anemia virus (EIAV)
What cells are infected in Feline Immunodeficiency virus?
CD4T-helper cells, CD8t-cells, B-cells, macrophages
What type of RNA virus is bullet shaped?
Rhabdoviridae
Which virus type has Negri bodies?
Rhabdoviridae
Rhabdoviridae is present in all countries except?
Australia and Antarctica
What is the genus of the Rabies?
Lyssavirus
Is rabies a fast or slow moving virus?
slow
Test used for rabies detection?
direct fluorescent antibody test- look for presence of rabies virus antigens in brain tissue
What Type of RNA virus is segmented?
Orthomyxoviridae
Influenza A affects what types of animals?
Humans, birds, mammals