Exam 4- RNA viruses Flashcards
What are the type of proteins on the envelope of retroviridae?
gag
3 important viral enzymes in retroviridae?
1) Reverse transcriptase
2) Integrase
3) RNA polymerase II (RNAPII)
_________ - any virus with DNA or RNA genome causing cancer
Oncovirus
________- gene that encodes for proteins regulating gell growth and differentiation and that can become an oncogene.
Proto-oncogene
________- are required for building in the genetic material.
Active cells
2 types of mechaisms of transformation for Retroviruses?
- Proto-oncogenes mistakenly incorporated into provirus
- Disruption of cellular proto-oncogenes
What is the genus and species of this disease?
Also the disease’s common name?

Alpharetrovirus
Avian sarcoma leucosis virus (ASLV or ALV)
AKA- Avian Leukosis
________– causes lymphoid leucosis and lymphoma (blood cell tumor from lymphocytes
Avian Leukosis
The genus and species of Enzootic Nasal Tumor?
G-Betaretrovirus
S-Enzootic nasal tumor virus (ENTV)
What is the host for Enzootic Nasal Tumor?
sheep,goats
The genus and species for Jaagsiekte?
G-Betaretrovirus
S- Jaagsiekte sheep retrovirus (JSRV)
_________– is a contagious lung cancer or ovine pulomonary adenocarcinoma.
Jaagsiekte
Clinical signs of Jaagsiekta?
Respiratory distress when you chase the animal, Lots of nasal discharge.
What is the genus and species? and common name?

G- Deltaretrovirus
S- Bovine Leukemia virus (BLV)
AKA- Bovine Leukosis
Symptoms of Bovine Leukosis?
-enlargement of lymph nodes
Ex: retro-ocular –> protrusion of conjunctional membrane
What is the genus and species of Feline Leukemia?
G- Gammaretrovirus
S- Feline Leukemie virus (FeLV)
What is diseas? its Genus, species also?

Equine Infectious Anemia aka swamp fever
G- Lentivirus
S-Equine infectious anemia virus (EIAV)
What cells are infected in Feline Immunodeficiency virus?
CD4T-helper cells, CD8t-cells, B-cells, macrophages
What type of RNA virus is bullet shaped?
Rhabdoviridae
Which virus type has Negri bodies?
Rhabdoviridae
Rhabdoviridae is present in all countries except?
Australia and Antarctica
What is the genus of the Rabies?
Lyssavirus
Is rabies a fast or slow moving virus?
slow
Test used for rabies detection?
direct fluorescent antibody test- look for presence of rabies virus antigens in brain tissue
What Type of RNA virus is segmented?
Orthomyxoviridae
Influenza A affects what types of animals?
Humans, birds, mammals
Influenza B affects what types of animals?
humans, seals
Influenza C affects what types of animals?
humans, pigs, dogs
Is swine flu affected by Influenza A, Influenza B, or Influenza C? or all?
A and C. Most common A, rare= C, B not found yet
A filamentous or pleomorphic type of RNA virus
Filovirdiae
What virus is shown? and its genus

Marburg Haemorrhagic Fever
G-Marburgvirus
“Respiratory Enteric Orphan” related to which virus?
Reoviridae
What virus is shown? and its genus?

Blue tongue
G- Orbivirus
What is the transmission route of Blue tongue disease ?
Arthropod bite
What is the following disease and its genus?

Viral Diarrhoea
G- Rotavirus
orthomyxo
segmented genome allows for antigenic shift
paramyxoviruses
non-segmented, one serotype > long term immunity
What is the following disease? Genus and species?

Canine Distemper
G-morbillivirus
S-canine distemper virus
What systems does canine distemper attack?
respiratory, gastrointestional, nervous
What is the following disease and its genus?

Rinderpest
G-morbillivirus
What are the 3 D’s of Rhinderpest?
Dead, Discharge, Diarrhea
What disease is shown? and genus?

New castle disease
G- Avulavirus
Is new castle disease contagious?
yes
The envelope on this type of virus is petal shaped spikes (peplomers)
Coronavirdae
Which type of virus is shown? and its genus?

feline infectioud peritonitis (FIP)
Alphacoronavirus
2 forms of FIP
1) Feline Enteric acoronavirus (FECV)
2) Feline Infectious peritonitis virus (FIPV)
clinical systems of dry non-effusive FIP
loss of appettie, weight loss, yelowing inside of eye, iris color change
clinical signs of wet or effusive FIP
damaged and leaking blood vessels, ascites, difficult breathing
Genus of SARS?
Genus Betacoronavirus
How are the surface proteins organized in Flaviviridae viruses?
icosahedral-like symmetry
How is Flaviviridae transmited?
Vector- mosquitos, dicks
Genus of west nile fever
Flavivirus
What symptons does west nile cause?
neurological symptoms
What virus is shown and genus?

Bovine Viral Diarrhea (BVD)
Pestivirus
What virus causes significant economic disease of cattle?
Bovine viral diarrhea (BVD)
What is the genus of Zika fever?
Flavivirus
__________ is a arthropod borne virus and replicates to maintain a cycle between host and vector
Arbovirus
__________ is endemic in animal populations
enzootic
_________- is epidemic outbreak of a disease in animal population
Epizootic
What is the following disease and its genus?

Foot and Mouth disease (FMD)
G-Aphtovirus
FMD is infectious via?
Excretions and secretions of infected animal
What is the genus of Poliomyelitis?
Enterovirus
What type of virus is difficult to grow in culture?
Caliciviridae
genus Vesivirus, Lagovirus, norovirus are part of what type of virus?
Caliciviridae
What disease is shown? genus?

Feline Calicivirus
G-Vesivirus
__________ diease is a important viral cause of respiratory infection in cats.
Feline Calicivirus
What RNA viruses are zoonoic?
Arbovirus, West nile fever, Rinderpest, Marburg Haemorrhagic Fever, Ebola, Rabies