exam 4 extras Flashcards
1
Q
re: pharmacogenomics, what do we need to look for with abacavir?
A
testing for HLA * B-5701
2
Q
how does efavirenz (non-nukes) crossing the BBB impact the body?
A
creates CNS effects –> suicidal thoughts, depression
3
Q
3 SE of integrase inhibitors
A
- increased liver enzymes
- weight gain
- hypersensitivity
4
Q
what accounts for all the protease inhibitor drug-drug interactions?
A
it manipulates the CYP 450 metabolism
5
Q
what is the Mechanism of action for the boosters?
A
block the CYP450
6
Q
name the 2 boosters
A
Norvir + Tybost
7
Q
tx for PCP
A
TMP/SMX
8
Q
tx for cryptococcal meningitis (fungal infection)
A
- itraconazole
- fluconazole
- ampho B
9
Q
tx for candidiasis
A
clotrimazole troches
10
Q
tx for CMV
A
- gancylovir
2. valgancyclovir
11
Q
tx for mycobacterium
A
azithromycin
12
Q
tx for HSV
A
- acyclovir
2. valacyclovir
