exam 3 extras Flashcards
which anti-infective can cause sensory and nerve dysfunction?
PCN
which anti-infectives have antabuse effects?
cephalosporins - cefatetan + cefazolan
metronidazole
which anti-infective class has an interaction with valproic acid?
carbapenems
which is the preferred tx for MRSA?
vancomycin
which is preferred tx for c. diff?
metronidazole
if treated C.diff with vancomycin, what is important?
needs to be ORAL
which abx are given over 1 hour?
vancomycin, fluroquinolones, metronidazole, clindamycin (SLOW)
“very fast must chill”
which abx have photosensitivity associated with them?
- tetracyclines
- sulfonamides
- fluroquinolones
which abx have CNS effects?
- sulfonamides
- fluroquinolones
- PCN (neurotoxicity)
which abx are associated with a rash?
- TMP/SMX
2. cephalosporins
which 2 drug classes are associated with Stevens Johnson Syndrome?
- (sulfonamideS) TMP/SMX
2. fluconazole
what temp does nystatin need to be stored at?
ROOM TEMP
what is normal BUN level ?
10-20
where should PCN G IM be given? (think large size)
ventro gluteal site
if someone receiving vancomycin IM starts to experience red man syndrome, what do you do?
SLOW DOWN infusion
what drug is contraindicated with itraconazole?
warfarin - can decrease prothrombin times
what is the only oral tx for ectoparasitic infection ?
ivermectin
re: pharmacogenetics, what genetic variation has an interaction with sulfonamides?
G6PD - can cause anemias
3 things to note with cefatriaxone?
- avoid with liver disease (b/c excreted by liver)
- avoid Lactated Ringers
- can cause bleeding
what are the 3 systemic fungal agents?
- amphotericin B
- itraconazole
- fluconazole
what are the 2 superficial fungal agents?
- nystatin
2. clotrimazole
mneumonic for meds that have drug-drug interactions
Imi Eats [drugs] If Feeling Shitty:
imipenum erythromycin itraconazole fluroquinolones sulfonamides
