Exam 4 Flashcards
Truvada
- emtricitabine with TDF
- taken once daily
- recommended to prevent HIV among all people with sex or IVDU
Descovy
- emtricitaabine with TAF
- recommended to prevent HIV through sexual transmission (not receptive vaginal sex)
Apretude
- Cabotegravir IM
- first injection followed by a second injection 1 month after the first and q2 months after
- prevent HIV among all people
What is PrEP
FDA approved med to prevent HIV in adults and adolescents weighing ≥77 lb
Substantial risk for HIV and ≤72 hours since exposure AND source is known to have HIV
- nPEP vis recommended
Substantial risk for HIV and ≤72 hours since exposure AND source is unknown to have HIV
case-by-case determination
Substantial risk for HIV and ≥73 hours since exposure
nPEP not recommended
nPEP regimens
- TDF/Emtricitabine once daily + raltegravir BID or dolutegravir daily
- TDF/Emtricitabine + Darunavir/ritonavir daily
- 28 days
HPV Vaccine
- recommended for routine vaccination at age 11 or 12
- does not treat existing HPV infections or diseases
Uncomplicated Gonorrhea
- endocervix
- asymptomatic or mildly symptomatic
- disseminated infection may occur (in women mostly)
Gonorrhea in men
- acute urethritis
- purulent discharge and dysuria
- spontaneous resolution after several weeks
Anorectal gonorrhea infection
- most patients are asymptomatic
- acute proctitus
pharyngeal gonorrhea infection
- orogenital sexual exposure!
- asymptomatic
- screened less frequently
Gonorrhea in newborns
- may be transmitted in utero, birth canal
- opthalmia neonatorum
Treatment of Uncomplicated Gonoccoal Infections of Cervix/Urethra/Rectum
- <150 kg ceftriaxone 500 mg IM x 1
- > 150 kg ceftriaxone 1 gm IM x 1
- if w/ chlamydia, give doxycycline 100 mg PO BID x 7 days (pregnant azithro 1 gm PO once)
Treatment of Uncomplicated Gonoccoal Infections of Cervix/Urethra/Rectum and Ceftriaxone is NOT availabile
- gent 240 mg IM x 1 + azithro 2 g PO x 1
- cefixime 800 mg PO x1
Expedited partner therapy
- cefixime 800 mg PO x 1 + chlamydia treatment if not excluded
Primary Syphilis
- painless lesion (chancre)
- disappear spontaneously without treatment (3-6 weeks)
Secondary Syphilis
- lesions anywhere on body including hands and soles of feet
- malaise, fever, pharyngitis, headache, anorexia
Latent Syphilis
- positive serologic tests but no other evidence of disease
- early latent patient is potentially infectious
- late latent, noninfectious except in pregnancy
Tertiary (Late) Syphilis
- slowly progressing, inflammatory phase of the disease
- can affect any organ in the body
Primary and Secondary Syphilis Treatment
Benzathine PenG 2.4 million units IM x 1 dose
Primary and Secondary Syphilis Treatment PCN Allergy
- doxy 100 mg BID x 14 days
- tetracycline 500 mg QID x 14 days
- azithromycin 2 g x 1 dose (resistance)
Early Latent Syphilis Treatment
Benzathine PenG 2.4 million units IM x 1 dose
if PCN allergy
- doxy 100 mg BID x 14 days
- tetracycline 500 mg QID x 14 days