Exam 2 Bacterial Coverage

Question 1

MRSA

Answer 1

• Vancomycin (DOC)
• Synercid
• Linezolid (cannot tolerate vancomycin)
• Daptomycin (cannot tolerate vancomycin)
• Lipoglycopeptides
• Ceftaroline
• Minocycline, analogs (rare)
• Clinda, TMP-SMX, delafloxacin (CA-MRSA)

Question 2

CA-MRSA

Answer 2

• clindamycin
• TMP-SMX
• delafloxacin

Question 3

Enterococcus Susceptible

Answer 3

• ampicilin
• amoxicillin (UTIs only)
• Vancomycin (patients who cannot use ampicillin)
• Synercid
• Linezolid
• Daptomycin
• Telavancin
• Doxycycline and analogs (rare)

Question 4

VRE

Answer 4

• if VRE is S to ampicillin, it is the drug of choice
• linezolid
• daptomycin (if patient is on SSRI)
• Synercid (3rd line, only active against faecium)
• oritavancin

Question 5

Pseudomonas

Answer 5

• ticarcillin
• piperacillin
• Zosyn
• Ceftazidime
• cefepime
• cefiderocol
• meripenem or doripenem
• aztreonam
• cipro, levo, dela
• gent, tobra, amikacin

Question 6

First line agents for pseudomonas

Answer 6

• Piperacillin
• cefepime
• amikacin

Question 7

second line treatment for pseudomonas

Answer 7

doripenem

Question 8

Drug of choice for MSSA

Answer 8

• nafcillin
• dicloxacillin
• cefazolin

Question 9

Second line for MSSA

Answer 9

• vancomycin

Question 10

Second line for MRSA

Answer 10

• linezolid

Question 11

First line for enterococcus

Answer 11

• ampicillin

Question 12

second line for enterococcus

Answer 12

• vancomycin

Question 13

first line for VRE

Answer 13

• ampicillin, if not Linezolid
• daptomycin (if patient is on SSRI)

Question 14

Legionella

Answer 14

• Cipro, levo, moxi, dela
• erythro, clarithro, azithro
• tetra, doxy, mino

Question 15

covers C diff

Answer 15

• vanc
• metronidazole

Question 16

Anaerobic monomicrobial infections due to bacteroides

Answer 16

• Metronidazole (DOC)
• clinda
• unasyn or zosyn
• carbapenems

Question 17

Bacteroides monomicrobial infections DOC

Answer 17

metronidazole

Question 18

bacteroides monomicrobial infections second line

Answer 18

• zosyn
• ertapenem

Question 19

Polymicrobial infections with bacteroides and gram negative aerobes

Answer 19

• unasyn alone
• zosyn alone
• carbapenems alone
• cefoxitin or cefotetan alone
• ceftriaxone or cefepime with metronidazole
• cipro/levo with metronidazole
• tetracycline analogs

Question 20

Polymicrobial infections with bacteroides and gram negative aerobes first line

Answer 20

zosyn alone

Question 21

Polymicrobial infections with bacteroides and gram negative aerobes need to be in combination with metronidazole

Answer 21

• ceftriaxone
• cefepime
• cipro
• levo

Question 22

C diff DOC

Answer 22

• oral vanc

Question 23

Treponema

Answer 23

• pen G
• 3rd gen cephalosporins
• macrolides
• tetracyclines