Exam 4 Flashcards
Efferent vessels carrying blood AWAY from the heart?
Arteries
Affarent vessels carrying blood TOWARD the heart.
Veins
Microscopic vessels connecting small arteries to small veins
Capillaries
Inside the blood verssel. Simple squamous tissue or endothelium, continuous with the endocardium
Tunica interna
the thickest, smooth muscle, collagen and elastiv tissue. Produces vasomotion: vasconstruction and vasodilation
Tunica media
Loose connective tissue, anchors vessels, and allows small nerves, lymphatic nerves, and smaller blood vessels to reach tissues of large vessels
Tunica externa
Large vessels that have their own network of small vessels
vaso vasorum
Why are arteries considered to be the resistance vessels of the cardiovascular systme?
Because they are relatively strong, resilient tissue structure that resists the high blood pressure within.
Biggest arteries, absorb some pressure but also maintain it. Ex. Aorta
Conducting (elastic) arteries
Midsized arteries that distribute blood to specific organs. Ex. femoral artery
Distributing (muscular) arteries
Smallest arteries; less than .1mm in diameter; arterioles are smallest example and do not have specific names
Resistance arteries
Short vessels linking arterioles and capillaries
metarterioles
An abnormal widening or balloning of a portion of artery due to weakness in the wall of the blood vessel
Aneurysm
Baroreceptors in internal carotoid artery wall; flossopharyngeal nerve transmits signals to vasometor and cardiac centers of brainstem
Carotid sinuses
Chemoreceptors near branch point of common carotid artery; vagus and glossopharyngeal nerves transmit signals to respiratory centers of the brain
Carotid bodies
Chemoreceptors in aortic arch; like carotid bodies, they signal respiratory centers of the brain
Aortic bodies
Exchange vessels; nutrients, waste, and hormones, move between blood and tissue fluid
Capillaries
Endothelial cells joined by tight junctions, but some intercellular clefts present
Continuous capillary
Endothelial cells have filtration pores facillitating exchange
Fenestrated capillary
Irregular, tortuous passages with wide gaps between endothelial cells
Sinusoid (discontinuous capillary)
What are the 3 routes that materials can travel through a capillary wall?
The intercullar clefts, the filteration pores, and through endothelial cytoplasm by trtanscytosis or diffusion
When a tissue is _____, precapillary sphincters relax (open) and capillaries fill with blood
Active
When a tissue is ______, precapillary sphincters close and blood flows from metarteriole to thouroughfare channel
Inactive
At rest what % of blood is found in the systemic veins?
64%
Veins are regarderd as the ________ of the cardiovascular system because they are relatively thin-walled and flaccid. They contain most of the blood?
Capacitance vessels
15um to 1mm in diamter; very porous, allow for exchange
postcapillary venules
Greater than 1 mm in diameter and have smooth muscle in wall (tunica media)
Muscular venules
Up to 10 mm diamerter, Individually named, and contains valves
Medium veins
Large lumens, very thin walls, no smooth muscle
Venous sinuses
Diameters greater than 15mm, have smooth muscle in all tunics
Large veins
What is simple path?
Artery to capillary to vein
What is portal system?
Sequence of two capillary beds
What is anastomosis
vessel merger without intervining capillary bed
What is the most common vascular disease?
Atherosclerosis;
What are the functions of lymphatic systems?
Recover fluid lost from blood capillaries; guard against pathogens, absorb lipids from small intestine
What are the components of lymphatic system?
Lymoh fluid, lymphatic vessels, lymphatic tissue, lymphatic organs
A clear colorless fluid, similar to blood plasma; low in proteins, supplies lymphocytes to bloodstream,
Lymph
Loosely connected overlapping endothelial cells
Lymphatic capillaries
What is the flow of lymph?
Lymphatic capillaries –> collecting vessels –> lymphatic trunks –> collecting ducts –> subclavian vein
Named by location: jugular, subclavian, bronchomediastinal, intercostal, intestinal, and lumbar
Lymphatic Trunks
Convergence of trunks in right thoracic cavity
Right lymphatic duct
Begins at cisterna chyli of abdomen
Thoracic duct
What is the flow of lymph aided by?
rhythmic contraction of lymphatic vessels
What lymphatic cells attack and kill cells and provide immunological surveillance?
Natual killer (NK) cells
Lymphatic cells that are thymus dependent. include Cytoxic, Helper, Regulatory and memory
T lymphocytes (T cells)
Cells that differentiate into plasma cells– connective tissue cells that secrete defensive proteins called antibodies
B lymohocytes (B cells)
Develop from monocytes and display antigens to T cells
macrophages
Branched Macrophages; found in epidermis, mucous membranes, and lymphatic organs
Dendritic cells
Stationary cells; stroma of lymphatic organs
Reticular cells
Aggregations of lymphatictes in the connective tissues of mucous membranes and various organs
Lymphatic (lymphoid) tissues
What is prevalent in passages of respiratory, digestive, reproductive, and urinary tracts
MALT; mucosa-associated lyphatic tissue)
What are regarded as primary lymphatic organs?
Red bone marrow and Thymus
Why are the red bone marrow and thymus regarded as primary lymphatic organs?
because they are the sites where B and T lymphocytes become immunocompetent
What are the secondary Lymphatic organs>
lymphnodes, tonsils, and spleen
What is the site of hemopoiesis?
red bone marrow
What does the red bone marrow do?
Supplies lymphocytes and other blood cells; reticular cells secrete colony-stimulating factors for leukocyte production
What is a bilobed organ located between the sternum and aortic arch?
The Thymus
What does the Thymus do?
houses developing lymphocytes and secretes hormones
What seals off blood vessels and secrete chemical messengers promoting development of T cells?
Reticular epithelial cells
What is the presence of thymus in a newborn necessary for development?
Immunity
At what age does the thymus start shrinking?
15
what are the most numerous lymphatic organs that are bean shped and less than 3 cm long
Lymph nodes
What are the two functions of lymph nodes?
to cleanse the lymph and to act as a site of T and B cell activation
What are some physical traits of the lymoh nodes?
outer cortex and inner medulla
What leads to the node but few leave?
Afferent vessels lead, efferent leave
What locations are nodes concentrated in?
cervical, axillary, thoracic, abdominal, intestinal and meseteric, inguinal, and popliteal
What are the patches of lymphatic tissue at entrance of pharynx?
tonsils
What are the three setsx of tonsils?
pharyngeal tonsil (adenoids), palatine tonsiles, and lingual tonsils
What is the largest lymphatic organ measuring up to 12 cm long?
Spleen
What is the concentration of erythrocytes?
red pulp
What consists of lymphocytes and macrophages/
white pulp
A population of disease-fighting cells that reside in the mucous membranes, lymphatic organs, and other localities in the body?
Immune system
What are two types of nonspecific defenses in the immune system>
Barriers to invasion by skin and mucous membranes and general actions against pathogens that penetrate
What is the specific immunity defense?
Ability to defeat and remember specific pathogens based on their antigens
What are the two forms of specefic immunity
Humoral and cellular
What is Humoral immunity?
Done by B lymphocytes and antibodies; antibodies are secreted by plasma cells and circulate freely in body fluids
What is cellular immunity?
Done by cytotoxic T cells; after developing in thymus, they are distributed widely, especially to lyph nodes; T cells attack enemy cells with lethal hit of toxic chemicals
With age, what happens to the quantity of red marrow, lymphatic tissue, and thymic hormones?
It declines.
What is a result of fewer T cells due to decline in red marrow
slower response to antigens, inreased risk of cancer
What does poorer discrimination in antigens result in?
increase in autoimmune disease incidence
What are exaggerated immune responses?
Allergies
What are the functions of the Respiratory system?
Gas exchange
Communication
Olfaction
Control pH of body
Aids in regulation of blood pressure by assisting angiotension II production
Helps create pressure gradients for flow of lymph and venous blood
Expulsion of abdominal contents
Division of the respiratory system that consists of passages that serve only for airflow, without the exchange of gasses.
Conducting division
Divsion that consists of gas exchange areas
Respiratory division
The airway from the nose through the larynx is often called the ?
upper respiratory tract
The regions from the trachae through the lungs compose the?
lower respiratory tract
What are the functions of the nose?
it warms, cleanses, and humidifies air; it detcts odors in the airstream; and it serves as a resonating chamber that amplifies the voice
What is the chamber just inside the nostril?
vestibule
septal cartilage, vomer, perpendicular plate of ethmoid bone?
Nasal septum
The Pharynx, or throat, has three divisions:?
nasopharynx, oropharynx, laryngopharynx
What is posterior to choanae and soft palate, houses pharyngeal tonsil, and is pseudostratified epithelium?
Nasopharynx
What is posterior to root of tongue, entry from mouth is through fauces, stratified squamous epithelium?
Oropharynx
What is form tip of epiglottis to esophagus and stratified squamous epithelium?
Laryngopharynx
What is the voice box, keeps food out of the airway with epiglottis?
The Larynx
What is one of the prominent cartilages on the larynx?
thyroid cartilage on anterior aspect
What does the larynx house inside?
the vocal cords and vestibular folds
What is known as the “windpipe”
The trachae
The trachae is a tube lying ____ to esophagus?
anterior
What are the c-shaped rings made of?
hyaline cartilage
What is trachealis?
smooth muscle on posterior aspect
What is internal median ridge on lowest tracheal cartilage?
Carina
What happens at the inferior end of trachae?
splits to form two main bronchi
What is the outermost connective tissue connecting trachae to neighboring organs
Adventitia
The lungs have a _____ apex, and _____ base.
superior; inferior
The costal surface is pressed against?
the rib cage
The midiastinal surface exhibits a slit called?
hilum
The hilum which receives the main bronchus, blood vessels, lymphatic vessels, and nerves constitute the ____ of the lung?
Root
The left lung has an indention called the _____ where the heart presses against it?
cardiac impression with notch
Lobes are separated by what?
fissures
The Left lung has how many lobes>
2
The right lung has how many lobes?
3
Each lung contains a branching sysstem of air tubes called?
the bronchial tree
Bronchus is wider and more vertical that the left one
main bronchus
How many total secondary (lobar) bronchi are there?
5, one for each lobe
What are all bronchi lined by?
ciliated pseudostratisfied columnar epithelium
What is the size of a bronchiole?
1mm or less in diameter
A bronchiole ventilates what?
a pulomonary lobule
Each bronchiole splits into over how many bronchioles?
50
What are the final branches of the conducting zone?
terminal bronchioles
What do respiratory bronchioles have?
alveoli
What are alveolar ducts?
elongated passages
What are clustered around atrium?
Alveolar sacs
What are 95% surface area; respiratory membrane is site of gas exchange–consists of type 1 cell and capillart cell
Squamous (type 1) alveolar cells
What is 5% of surface area, outnumber type 1 cells, produce a surfactant, and repair alveolar epithelium
Great (type II) alverolar cells
Each lung is enfolded in a two-layered seous membrane
the pleura
The layer on the lung surface
visceral pleura
Layer on inner surface of rib cage
parietal pleura
Space between the parietal and visceral pleurae which contains pleural fluid is called the?
Pleural cavity
What are the three functions of pleurae and pleral fluid?
Reduction of friction, creation of a pressure gradient, compartmentalization.
What is the prime mover for pulmonary ventilation?
Diaphragm
Contraction= ____; Relaxes for _____
inspiration; expiration
What is the primary respiratory pacemaker>
Ventral respiratory group (VRG)
What signals VRG to modify breathing>
Dorsal respiratory group
Signals DRG and VRG to modify breathing?
Pontine Respiratory Group (PRG)
Brainstem neurons that respond to pH of CSF?
Central chemoreceptors
Neurons in wall of aorta and carotoid arteries that respond to pH, O2, and CO2, content of blood
Peripheral chemoreceptors
The central receptors, peripheral chemoreceptors, stretch receptors in respiratory system, irritant receptors, and higher brain centers are part of what?
Respiratory input sources
When does fetal breathing begin by?
11 weeks; amniotic fluid is inhaled and exhaled
What do restrictive disorders do?
Stiffen lungs and reduce compliance (ease of inflation)
Obstuctive disorders do what?
narrow the airways and interfere with airflow