Exam 4 Flashcards
Nerve terminals go to dendrites next door ; synaptic connections are between neurons
Axodendretic
goes ot the cell body of the cells
Axosomatic
Goes to the axon hillock cna add mv
Axoaxonal
NT’s are classified based on
Chemical structure
What are the biogenic amines
Dopamine, norepinehrine, epinephrine, seratonin , histamine
What are the excitory amino acids
glycine, aspartate, and glutamate
What is the main inhibitory amino acid
GABA
What are the main neurotransmitters
Acetylcholine
Biogenic Amines
Amino acids
Where is smooth muscle found
In the walls of hollow organs
Main characteristics of smooth muscle
No neuromuscular junctions
innervated by autonimic nerves
- have varicosities
-wide synaptic cleft
- less developed SR
- no t-tubules
Where are some places contractions occur in
Bladder
uterus
rectum
bronchi –> asthma
stomach –> cramps
involuntary alternating of contraction/ relaxation of muscle sheets
Peristalsis
Are spindle shaped
have one central nucleus
much smaller than skeletal cells
sheets found in hollow organs except capillaries
Smooth muscle cells
One sheet of muscles cells runs parallel to long axis or organ
- contraction –> dialation –> elongation
Longitudinal layer
fibers run around circumference of organ- contraction –> constriction –> elongation
Circular layer
The lumen gets shorter and wider when muscles cells of the _______ layer constricts
Longitudinal
The lumen gets smaller when the muscles cells of the ______ layer constrict
Circular
What stores calcium in muscles cells
The Caveoli
An electrical network that is between each sheet of smooth muscle and release neurotransmitters into a wide synaptic cleft
Varcosities
What type of junctions are in smooth muscles
Gap junctions
What is area 22 in the brain
Wernicke’s area
Are the controls the muscles needed for speech (tongue, throat, lips, etc)
Broca’s Area
What is area 44 and 45 in the brain
Broca’ s Area
Damage to the Broca’s Area causes….
Broca’s Aphasia
Person can understand language but cannot produce intelligible language. (motor issue)
Broca’s Aphasia
Where speech is interpreted and understood
Wernicke’s area
Loss of ability to understand written or spoken language and produce coherent word sequences (word salad - the person doesn’t know what you are saying so random words are put together)
- Normal grammar, syntax, rate, and intonation is used but randomly put together
Wernicke’s Aphasia
How are the Borac’s area and Wernicke’s Area conncted
By the arcuate fasiculus
Where did Broadman start when finding the 52 areas of the brain?
Post Central Gyrus
What area is area 8 in the brain?
The frontal eye field
Where is the Primary Somatosensory cortex located
The Post Central Gyrus of parietal lobe areas (1-3)
What is the part of the brain that is receiving the electrical current from all the sensory Nuerons in the skin, muscles, and joints
Primary Somatosensory Cortex (2, 3, 1)
What is the cortex that is posterior to the Primary somatosensory cortex?
Somatosensory Association Cortex (5,7)
Function is the integrate sensory information and involves the interpretation/ memory of a particular sensation
- SSC is used for to recognize the sensation of the object
Somatosensory Association Cortext
Where is the Primary visual cortext located?
area 17 (occipital lobe
Where is the Visual asossitation area located?
Beside the visual cortex in the occipital area ( 18)
area that is responsible for neurons that immediately respond to electrical current that is coming out of the optic nerve that comes from the retinas
Primary Visual Cortex
Interprets visual stimuli using stored memory for recognition (memory of the things we see)
Visual association area (area 18)
What type of blindness does damage to area 17 (occipital lobe) causes
Cortical Blindness
Where is the primary autidtory area located in the brain?
Above the temporal lobe
This area receive sensory information and damage can result in deafness
- pitch/ loudness
Primary Auditory Area (41, 42)
Where is the auditory association area located?
Behind the Primary Auditory cortex
This area uses stored memory to interpret perceived sound ( memory of things we hear)
- Music, Thunder, Trains, airplanes
Auditory association area (42 and 22)
Where is the olfactory cortex located?
In the frontal lobes (medial temporal) above the orbits
This area is where sense of smell is percieved and allows us to be aware of different smells
Olfactory Cortex
Where is the Gustatory Cortex loacted
Inferior parietal lobe
This area is where sense of taste is perceived and allows us to be aware of different taste
Gustatory Cortex
Where is the memory of smells and taste stored
In the limbic system aka. emotional brain
What cortex is in the insula and processes information that keeps us in balance in all three planes we move in
Vestibular Cortex
What is the cortext that is in the anterior frontal lobe and is involved with intellect, personality, judgement, etc.
-Makes us who we are
The prefrontal context
Damage to this part of the brain can cause mental and personality disorders
Prefrontal cortext
What are graded depolarizations called in excitatory synapse
Excitatory Postsynaptic Potentials (EPSP’s)
Where the neurotransmitters released at the presynaptic membrane causes depolarization at the postsynaptic membrane.
Excitatory Synapses
Where the neurotransmitter release at the presynaptic membrane causes hyperpolarization of postsynaptic membrane
- less likely to reach threshold
Inhibitory Synapses
What are graded hyperpolarizations called
Inhibitory Postsynaptic Potentials (ISPS’s)
this nuerotransmitter is released at the neuromuscular junctions - excitatory and is degraded by AchE
Acetylcholine
What are examples of biogenic Amines
Dopamine, Norepinephrine, epinephrine, serotonin histamine
What are the inhibitory amino acids
GABA
What are the excititory amino acids
Aspartate, glycine, glutamate
What is a local depolarization of the post synaptic membrane that brings the neuron closer to action potential threshold and allows sodium and potassium to pass simultaneously when a neurotransmitters binds to it.
Excitatory synapse
what makes a molecule a nuerotransmitter?
It is made and release by a neuron and there is a receptor on a postsynaptic membrane that the molecule can go to .
Hollow chambers filled with cerebrospinal fluid, lined with ependymal cells and are continous with each other and the central canal
Ventricles
What is made by the choroid plexus
Cerebrospinal fluid
Clusters of leaky blood capillaries covered in pia mater and ependymal cells
choroid plexus
What are other functions of cerebrospinal fluid
- floats the brain
- forms a liquid cushion
- helps transport molecules
- completely replaced every 8 hours
What is 83% of total brain mass
Cerebral hemispheres
“gyri”
Ridges
” Sulcus”
Grooves
What divides the left and right hemisphere of the brain
The longitudinal fissure
What are the 5 lobes of the brain
Frontal
Parietal
Temporal
Occipital
Insula
what divides the frontal and parietal lobes
the central sulcus
What divides the temporal lobe from the frontal and parietal lobes
The lateral sulcus
What divides the parietal and occipital lobes
the parietal-occipital sulcus
What seperates the cerebrum from the cerebellum
The transverse cerebral fissure
What are the three functional areas of the cerebral cortex
Motor, sensory, association
Different histological and functional areas of the cortex where specific motor and sensory functions are separated into domains
Broadmann’s 52 area
The cerebral cortex is made of mostly…
interneurons which are small neurons that connect 1 neuron to another
What are the critical areas that control motor functions
- Primary motor cortex
- Premotor cortex (secondary motor cortex)
- Broca’s area
- Wernicke’s area
- Frontal eye field
Located in the precentral gyrus of frontal lobe (area ) and has the biggest motor neurons that control contralateral voluntary movement of skeletal muscle
Primary motor cortex
Trauma to this area can result in the loss of voluntary control
Primary motor cortex
Located in the anterior/ precentral gyrus in the frontal lobe (area 6)
Premotor cortex (secondary)
Controls learned motor skills and coordinates movement of groups of muscles by sending impulses to the primary motor cortex
Premotor cortex
aka = memory bank for skilled motor actitives
Trauma to this area cna result in loss of programmed motor skills but not individual movements
Premotor cortex
Found in the left hemisphere (area 44, 45) and controls that muscles needed for speech (tongue, throat, lips)
Broca’s Area
Damage to this area cause a person to be able to understand language but cannot produce intelligible language
- labored speech
- halting and disjointed words
Broca’s Aphasia
Where speech is interpreted and understood (area 22) and coherent speech is produced
Wernicke’s area
Damage to this area causes loss of the ability to understand written or spoken language and produce coherent word sequences.
- Normal grammar syntax rate, and intonation
- word salad
Wernicke’s Aphasia
What connects wernicke’s area to broca’s area?
Arcuate fasiculus
Controls voluntary eye movement (area 8)
Frontal eye field
Area controlling sensory input in skin, muscles, and joints sensation
- Primary Somatosensory Cortex
Located in the post central gyrus of parietal lobe ( areas 1-3) and receives afferent information from somatosensory receptors ( skin, joints, and muscle)
Primary Somatosensory Cortex
What are the primary brain vesicles
The prosencephalon, mesencephalon, and the rhombencephalon
What are the secondary brain vesicles
telecephalon, diencephalon, esencephalon, metencephalon, myelencephalon
Cerebral hemispheres (cortex, white matter, basal nuclclei)
Cerebrum
adult brain strucutre that has the thalamus, hypothalamus, epithalamus, and retina
Diencephalon
brain stem: midbrain
Mesencephalon
Brain stem: pons
Metencephalon
where is the cerebellum?
In the metencephalon