Exam 4 Flashcards
What muscles are striated?
Skeletal muscle and cardiac muscle
What muscles are unstriated?
Smooth Muscle
What muscles are voluntary?
Skeletal muscle
What muscles are involuntary?
Cardiac and smooth muscle
muscle cell
myocyte
Junction between a motor neuron and a muscle fiber
Neuromuscular junction
look at phys 5
look at phys 6
62,63,72,79-82,84
13-17, 26-31, 43, 50, 56, 58, 63-64
the part of the muscle that generates the force
Muscle Body
What is the structure of the skeletal muscle?
Muscle -> Muscle body -> fascicles -> muscle cells -> muscle fibers -> myofibrils -> t-tubules
the equivalent of the plasma membrane in muscle cells
Sarcolemm
Equivalent of the plasma membrane in muscle cells
Sarcolemma
Equivalent of cytoplasm in muscle cell
Sarcoplasm
What does the sarcoplasm do?
it stores glycogen and myoglobin (O2)
What does the Sarcoplasmic Reticulum do?
it stores Ca ions
Allows action potentials to reach the interior of the muscle
Transverse T-Tubules
Voltage sensitive protein on T-Tubule that responds to a depolarization
DHP
Calcium channel located on SR and connected to T-tubule
Ryanodine
what does the Ca-ATPase pump do?
Pumps Ca ions from the sarcoplasm into the SR
unit of the muscle: composed of overlapping thin and thick filament
Sarcomere
what do A bands contain?
Thin and thick filament
What does the H zone and M line contain
Thick filament
What does the I band contain?
Thin filament
Ca binds to it?
Troponin
Has the ability to cover/uncover the myosin binding site
Tropomyosin
What makes up thin filament?
Actin
what makes up thick filament?
Myosin
sequence of events whereby an action potential in the sarcolemma causes contraction
Excitation-Contraction Coupling
Three levels of Muscle Metabolism in order
Creatine phosphate
Anaerobic Respiration
Aerobic Oxidation
Describe the phases of a muscle Twitch
Latent period- chemical spread of motor neuron and AP
Contraction- Ca release
Relaxation- Ca reabsorption by SR
What is the longest phase of a twitch
Relaxation period
generate less force and fatigues faster, red fiber
Slow Oxidative Fiber
Increased force but fatigues faster, white fiber
Fast Glycolytic Fiber
Intermediate Trainable pink fibers
Fast Oxidative Fiber
Three factors that affect the force generated by individual muscle fibers
Frequency of stimulation
Fiber Diameter
Change in fiber length
frequency of stimulation phases
Twitches, summation, tetnus, fatigue
caused by troponin saturation with Ca
Complete tetanus
larger fiber diameter leads to what
increased myofilaments which increase sarcomeres and force
What does working out do to your muscles?
increases the fiber diameter
What does optimal length of fibers do?
Increase force of contraction which forms greatest number of crossbridges
When thin filaments begin to overlap each other
Below optimal Fiber Length
When thin and thick filaments don’t overlap as much
Above optimal fiber Length
Motor neuron and all muscle fibers it innervates
Motor unit
Activating more motor units to generate more force
Motor unit recruitment
What is the size principal?
Order of recruitment
What is the practical implication of this principal?
Use as much force as needed to accomplish a task
Which muscle type maintains its force for a longer period of time?
Smooth muscle
Contraction from a neuron?
Neurogenic
What muscles are neurogenic?
Skeletal and multi-unit smooth
Contraction due to muscle cell spontaneously depolarizing
Myogenic
What muscles are myogenic?
Cardiac and single-unit smooth