Exam 3 Flashcards
What makes up the central nervous system?
Brain and spinal cord
What makes up the peripheral nervous system?
cranial and spinal nerves
Somatic and visceral sensory nerve fibers that conduct impulses from receptors to the CNS
Sensory (afferent) division
What three things effect sensory divison?
Somatic senses- Skeletal muscle
Visceral senses- stomach
Special senses- outside info
Conducts impulses from the CNS to the effectors
Motor (efferent) division
What is the functional unit of the nervous system?
neuron
What are the support cells of the nervous system?
Glial cells
Receive input form other neurons and generates graded potential
Dendrite
Carries out most cellular function and generates graded potential
Soma
Initiates action potential
Axon hillock
Propagates action potentials
Axon
Forms the myelin sheath around the axon (in CNS)
Oligodendrocytes
Forms the myelin sheath in PNS
Schwann
Insulates the axon to enable faster and more efficient action potential transmission
Myelin sheath
Releases neurotransmitters into the synaptic cleft
axon terminal
What part of cells make up gray matter?
Dendrites/soma
What part of cells make up white matter?
axon/oligodendrocytes
what is the function of gray matter
Synaptic transmission
What is the function of white matter?
propagate action potential
where is gray matter located?
Outer layer in general and the inner layer of the spinal cord`
clusters of cells in the CNS
Nuclei
Pathways in the CNS
Axons that travel in bundles
Clusters of cells in the PNS
Ganglia
Nerves in PNS
Axons that travel in bundles
What is the net charge of the ICF?
negative
What is the net charge of the ECF?
Positive
How does a cell do work
It has to have a membrane potential
What cells are excitable
Muscle and nerve cells
Chemical force
based on concentration
Electrical force
based on electrical charge
Based on both the chemical and electrical force
Electrochemical
What are the equilibrium potential for rest, Na, and K?
Rest- -70mV
Na- +60mV
K- -90mV
How does the Na/K pump maintain the EC gradient for Na and K.
By pumping out 3 Na and in 2 K
Explain how leak channels establish a negative RMP
there are more K+ leak channels than sodium and hydrated K+ is smaller than Na
Leak channels are ______
always open
Change in response to a ligand binding to them
Ligand gated channel
Change in response to membrane potential
voltage gated channel
What type of channels are always open and are found along the whole neuron?
Leak channels
What type of channels are found along dendrites/soma and recieve info from pre-synaptic neurons
Ligand gated channels
What type of channels are found on the axon hillock and axon and initiate and propagate action potentials
Na/K voltage gated
What type of channels are found on afferent neurons and take part in sense?
mechanically gated channels
What type of channels are found on the axon terminal and release neurotransmitters?
Ca+ voltage gated channels
What is threshold to make a action potential?
-55mv
Membrane potential is more positive due to Na influx
Depolarization
When membrane potential returns to RMP or is more negative due to K+ efflux
Repolarization
Membrane potential is more negative than rest due to K+ efflux
hyperpolarization
Can’t generate a new action potential
Absolute refractory period
Can generate another action potential with a larger simulus
Relative refractory period
How can a larger stimulus cause another action potential?
-Due to K+ efflux the membrane is more - than normal
-Not all Na channels are at rest so larger stimulus reaches them
Saltatory conduction
action potentials jump from node to node
action potential travels the entire length of the axon
Continuous conduction
Myelin sheath is damaged and speed of action potential slows
Multiple Sclerosis (MS)
What happens to a graded potentials strength as it moves towards the axon hillock?
It loses it strength
What dictates the magnitude of the graded potential?
the strength of the stimulus
Summation that occurs from the same stimulus
temporal summation
Summation that occurs from different stimuli
Spatial summation
What are the two types of PSPs
EPSP and IPSP
Increases the likelihood of the postsynaptic neuron generating an action potential
Excitatory PSP
Decreases the likelihood of the postsynaptic neuron generating an action potential
Inhibitory PSP
How is a NT removed from the cleft
Degrade via enzyme
Reuptake by pre-syn neuron
Diffuse away
How do you make acetylcholine
Acetyl CoA + Choline
What are the two types of Ach
Nicotinic- fast
muscarinic- slow
What are biogenic amines?
Play a behavior in mental illness
HAVE- YAY LACK- SAD
How many adrenergic receptors are there and whats their speed?
Slow and 5
wrinkly part of the brain that preforms higher functions
Cerebral cortex