EXAM 4 Flashcards
- person being measured differs from the standard reference body only in the amount of fat
- density of fat is 0.901 gm/cc
- density of fat-free body is 1.100 gm/cc
assumptions for all body compositions
- estimating body composition from body density
- principle/theory: density = mass/volume
- underwater weighing, hydrostatic weight or hydrodensitometry
- bod pod
densitometry
Accuracy of H20 weighing:
- considered the _ of body composition assessment <1% BF
- pros: accurate, based on assumptions
- cons: original reference body was based on a few cadavers, only one female
- can be difficult for individual who is hydrophobic
- can be expensive for all of the equipment
“gold standard”
- same principle as hydrostatic
- determine body volume differently
- body volume determined in a capsule
- accuracy, similar to hydrostatic
- expensive ($65K)
Bod Pod
_ principle/theory:
- percentage of body weight that is 70-75% at birth
- methods that determine total body water can in turn, predict body fat and lean mass
- tracers/dilution
- BIA
- TOBEC
hydrometry
Total body water measurement by dilution:
- tracer is distributed only in the _
- tracer is _ distributed in all anatomical water compartments
- rate of equilibration of the tracer is rapid
- neither the tracer nor the body of water is _ during the time of tracer equilibration
- body of water
- equally
- metabolized
Types of _:
- Tritium
- Deuterium
- Oxygen-18
- accuracy: can be as accurate as a precision of 1-5%
tracers
Tracers:
- Pros: does not require _
- Cons: can be _, does us radioactive isotopes (can be fearful for some)
- subject cooperation
- expensive ($5-100)
Bioelectrical Impedance and Total Body Electrical Conductivity:
- principle/theory:
- tissues high in water are _
- electrical current flows the path of _
- volume of tissues can be determined from measurements of combined resistances
- accuracy of BIA: 1-2% precision, 3.5-5% accuracy
- assumptions:
- assumes that the _ has uniform conductivity, is homogenous, a constant cross-sectional area, and known length
- no conduction in the “non conductive” components of the body
- highly conductive
- least resistance
- cylinder
- first used to asses the lean mass of hogs
- in 1985 commercial devices to measure body comp in animals, children and adults
- in 1994, took off the market
- can be influenced significantly by electrolytes
TOBEC
TOBEC:
- principle/theory:
- underlying principle is the _, conductivity of a tissue is dependent on its water content and free electrolyte concentration, temperature, and frequency of the current
- _ to the volume of the fat and the bone-free body mass
- accuracy: 2.5% body fat is considered marginally superior to BIA
- method: an electric current is induced into the body using an _ rather than a current using electrodes
- same as for BIA
- directly proportional
- electromagnetic field
Pros/Cons of all hydrometry
- pros:
- BIA: easy, little subject cooperation
- TOBEC: easy to use, little subject cooperation
- cons:
- BIA: _ can significantly alter results, as an electrode placement
- TOBEC: expensive and equipment is _ by manufacturer
- hydration levels
- no longer supported
challenges of hydrometry
- body is not cylinder, with uniform CSA
- smaller cylinder (arm) = _
- arm is 4% of weight
- leg is ~17%
- arm has 47% resistance, leg ~50%
- trunk is 46% of BW, little to no influence on resistance
- appropriate for _ studies
- most of the resistance
- epidemiologic
Whole body counting and neutron activation analysis:
- based on early whole body counters to count radiation exposure
- principle/theory:
- _ measurement of the body’s radioactivity. including naturally occurring potassium
- Three types of potassium in the body:
- 93.1% is 39K
- 6.9% is 41K
- 0.0118% is 40K
- isotope 40K is _
- TBK for average male is ~ 140g, average female ~ 100g
- in-vivo
- radioactive
Whole body counting and neutron activation analysis:
- assumptions/accuracy:
- while precision is very good, _ is not as good, 4-6% greater in the young
- Pros/cons
- Pros: easy, precise
- Cons: Expensive ($30,000-300,000)
accuracy
Dual energy X-ray absorptiometry (DXA)
- principle/theory:
- calculate the mineral content and then the _ can be measured with each pixel
- estimate fat, not adipose tissue (CT)
- calculate _ tissue and _ tissue
- pure fat
- lean, fat
Dual energy X-ray absorptiometry (DXA)
- assumptions:
- _ does not change body comp data (minimal)
- measurements not affected by anterior-posterior thickness of the body
- area of the body analyzed to determine _ and the degree to which the fat content of the area analyzed is associated with the fat content of the area that is not analyzed
- Accuracy:
- 2.5-3.5% SEE
- Pros/Cons
- Pros: easy to do, does not require subject cooperation
- Cons: expensive ($150,000)
- hydration levels
- body comp
CT Scan
- Pros: _
- Cons: radiation, expensive
accurate
Anthropometric: circumferences, skinfolds, stature
- can be applied to laboratory and field settings
- principle/ theory and assumptions:
- tissues included in the measurement are in the _, muscles are relaxed and soft tissues are normally hydrated
- the bigger it is, the _ the body fat
- accuracy: skinfolds
- technician and equation _, +/- 3.5% error
- Pros/Cons: skinfolds
- Pros:
- easy to perform, can test a large population, _
- Cons:
- depending on equation utilized, can have errors
- large technician error
- “standard” state
- greater
- dependent
- inexpensive
- developed in agricultural research
- product uses same wavelength for animals as humans
- accurate for animals, not accurate for humans
infared
- anorexia nervosa
- bulimia nervosa
- binge-eating
disordered eating
- psychotherapy
- nutritional counseling
- medical supervision
- athletic trainer/exercise physiologist
- did you know… 4/10 americans have either suffered or have known someone who has suffered from an eating disorder
treatment for disordered eating
Drive for thinness:
- 42% of _ grade girls want to be thinner
- 81% of _ are afraid of being fat
- 1st-3rd
- 10 year olds
Newer facts for drive for thinness
- average american woman is _ and weighs _
- the “ideal girl” (described by caucasian teenage girls) is _ and weighs _, and wears a size 5
- at age 13, 53% of american girls are “unhappy with their bodies”
- increases to 78% by the time girls reach age _
- 5’4”, 163lbs
- 5’7”, 110lbs
- 17
Facts about women and ideals:
- 1 in 40,000 women meet the requirements to be a fashion model
- average woman is a size _ (Marilyn Monroe)
- models 20 years ago weighted 8% less than average woman; today they weigh _
- if mannequins in shops were real, they would not menstrate
- 14
- 23% less
- Ana Carolina Reston: died 11/15/06 at age 21, weighing 88 lbs
- Luisel Ramos: died 8/26/06 at age 22, 98 lbs
- Eliana ramos (sister of Luisel): died 2/13/07 at age 18, 84 lbs
- Mariara Galvo Vierira: died 1/6/07 at age 24, 84 lbs
- Hila Elmalich: died 11/04/07 age 34, 60 lbs
Tragedy of modeling
- at risk: athlete (not necessarily competitive)
- controlling figure in her life (often male)
- strives for perfection
- physiologic vulnerability
female athlete triad
Energy Balance equation
- weight change =
total energy intake - total energy expenditure
Weight management: intervention strategies
- _: appetite, thermogenesis, resting metabolism
- _: food absorption
- _: food intake, physical activity
- drugs
- surgery
- behavior therapy
Control of food intake;
- control center is the _
- hunger center
- satiety center
hypothalamus
Resting energy expenditure:
- _ necessary to live, resting
- anything above is additional energy requirements
metabolic requirements
- most common treatment for excess weight
- consumption of diet is also important
- not “one size fits all” evidenced by twins study
- most regain weight after
caloric restriction
physical activity began during caloric restriction and maintained after resumption of previous caloric intake
Most effective for maintenance of weight loss
Greatest rates of overweight/obesity after _, people ate more typical “American diet”
- Prima indians
WWII
Chronology:
Ancel Keys, fat is bad, the Mediterranean diet is better (post-WWII)
- Naples
- poorer were heavier
- 2,400 kcals vs 3,800 kcals
- working-class women were overweight
1951
Chronology:
Prima Indians
- more than 1/2 of boys and girls obese
- widespread poverty
1954
Chronology:
Durbin, SA
- among Zulu 40% of women Obese
- numerous signs of malnutrition
- ~20% heavier and 4” shorter than men
1960
Chronology:
Nauru, South Pacific
- everyone past puberty is grossly overweight
1961
Chronology:
Trinidad, West Indies
- malnutrition and obesity serious problem
- ~ 1/3 of women obese
- caloric intake <2,000 kcal/day
1961-1963
Chronology:
Chile
- obesity: main nutrition problem of adults
- factory workers
- 35% males OB
- 39% female OB
- significant physical labor
1963
Chronology:
Joburg, SA
- Urban Bantu prisoners 60+ year olds
- 30% women OB
1964-1965
Chronology:
North Carolina
- 29% adult Cherokee on Qualla Reservation OB
1965
Chronology:
Ghana
- 25% women and 7% men OB
- 1/2 of all women in 40’s OB
1969
Chronology:
Lagos, Nigeria
- 5% men OB
- 30% women OB
- women: 55-65 year olds - OB
1970
Ketogenic Diet:
- _: 70% fat, 20% protein, 10% CHO
- _: SKD for 5 days, 2 days high CHO
- _: add CHO for workouts
- _: 60% fat, 35% protein, 5% CHO
- standard keto diet
- cyclical keto diet
- targeted keto diet
- high protein keto diet
- epilepsy
- cancer cachexia
- cancer with tumor metabolism drugs
- inflammatory diseases
- CAD
- diabetes
positives for keto diets
- can be dangerous
- loss of lean body mass
- associated with serious cardiac arrhythmias
- many people have died of cardiac arrest
- loss of hair
- thinning of skin
- coldness in the extremities
- gallbladder stones
- gout
- elevated cholesterol
very low calorie diets
- religious and/or health
- alternate day fasting
- 1 day/wk or 5 days every 5 week
- 25% of energy restriction: alternating days, SaMW
- time-restricted eating, 8-22 hrs
- often for weight loss
intermittent fasting
Intermittent fasting:
- hypothesized to influence _ via effects on:
- cicadian biology
- the gut microbiome
- modifiable lifestyle behaviors
- negative perturbations of these biological and physiological systems
- hostile _
- _ individuals to developing obesity, diabetes, cardiovascular disease, and cancer
- metabolic influence
- metabolic milieu
- predisposes
- diuretics
- impermeable clothing
- weight loss is due to this, but not fat loss
- usually re-hydrate after the loss
dehydration
- prolonged fasting
- gastric/bariatric bypass
- lipectomy (liposection)
medical procedures
- appetite suppressants
- thermogenic drugs
- orlistat (xenical & Alli): fat absorption in the gut 30% less
- 7-10# more than if diet alone
- Sexenda: slows gastric emptying
drugs to control weight
Behavior modification:
- focus on elimination of behavior that is associated with _ and _
- many theories of behavior change
- 30% of participants _ after one year and continue to lose
- poor eating, exercise habits
- maintain weight loss
Exercise:
- vigorous exercise _
- single session of exercise will result in little fat loss
- regular exercise training will lead to adaptations that increase with utilization of fat
- 1977: NIH OB & Wt control
- increase in _ leads to an increase in _
- stimulate appetite
- energy expenditure, energy consumption
- begin to utilize fats earlier in the exercise bout
- utilize more fats
- females utilize more fats more efficiently than males
exercise adaptations
- females are more efficient at _
- females store _
- females may store more from a similar meal of fat than a male would
- storing fat
- more fat
Fat metabolism:
- _ process and store lipids
- procedure a variety of _
- _: reduced or absent fat deposits
- insulin resistance
- Type II diabetes
- adipocytes
- hormones
- Lipoatrophy
Leptin gender differences
greater in females
Best activity for weight loss
- 1 mile = ~ 100 kcal
- whether walk/run the mile
HITT
- should be small
- should become part of your lifestyle
- ~21 days to make a habit
- eat at the same time everyday
reasonable changes
- meal planning
- physical activity
- behavior therapy
- lifestyle therapy
- pharmacotherapy
- weight reduction surgery
- weight maintenance plan
weight loss strategies
- eat a colorful diet
- close to the ground
- if it’s white, it’s probably not right
recommendations
_ is more important than a “diet” or weight loss
- better long-term outcomes and long-term health
- if it took 5 years to gain weight, unlikely to lose it in 3 months
weight maintenance
Altitude:
< 12,000 ft = _
12,000-18,000 = _
> 20,000 ft = _
- moderate
- high
- very high
Stress at altitude:
- The 4 “H”s
- hypoxia
- hypothermia
- hypoglycemia
- hypohydration
Stress at altitude:
- additionally
- suppressed _ and _
immune system, emotional state
Stress of altitude:
- O2% at sea level = 21%
- O2% at 22,000 ft = 21%
- decreased PO2 results in _
hypoxia
Adaption to the new natural environment
acclimatization
Acclimatization:
- respiratory
- hyperventilation
- body fluids become more base as a result of reduction in CO2 with hyperventilation
- cardiac
- increased heart rate at rest and a submax work = increased cardiac output
- stroke volume remains the same or decreases
- max VO2 remains the same
immediate
Acclimatization:
- respiratory
- hyperventilation
- excretion of base via kidneys and concomitant reduction in alkaline reserve
- cardiac
- increased submax heart rate
- submax cardiac output falls
- stroke volume decreases (Starling’s law)
- max VO2 decreases (decreased max HR and stroke volume)
longer term (days to weeks)
Acclimatization:
- decreased plasma volume
- increased plasma volume
- increased # of RBCs
- possible increase in capillary density
- increased 2,3 DPG
- increased mitochondrial density
- increased aerobic enzymes in muscle
hematological response
Acclimatization:
- nor-epinephrine
- increased 7 days and then stabilizes
- epinephrine
- shows little to no increase
- regulates HR, BP, SV, vascular resistance, and substrate use
catecholamine response
Acclimatization (Acid Base Balance):
- _ leads to a decrease in CO2 thus increasing pH of all bodily fluids
- this blunts respiratory control
- body begins to excrete base through _ to normalize pH
- this increases respiratory sensitivity and allows for greater hyperventilation
- this decrease in “base” creates a loss of the _ reserve inhibiting the body’s buffering ability
- this is made up for by a decrease in _ and a reduction in _
- hyperventilation
- renal tubules
- absolute alkaline
- intercellular ADP, epinephrine output
Acclimatization schedule:
- rapid ascent 0-7,500 ft _ to adjust
- then _ per 2,000 ft up to 15,000 ft
- 2 weeks
- 1 week
Acclimatization schedule:
climb to camp altitude
- active acclimatization
- move to next camp
- repeat as necessary
- summit
- get outta dodge
stage ascent
all are exacerbated by:
- speed of ascent
- altitude
- health of individual
- general susceptibility of individual
altitude related illness