Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Cell Bio > Exam 3 vocab > Flashcards

Exam 3 vocab Flashcards

You may prefer our related Brainscape-certified flashcards:
Biology 101 flashcards
1
Q

Integrin

A

Major transmembrane protein allowing a cell to attach to the ECM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Laminin

A

Adhesive/ attachment proteins used in construction of ECM materials. Has several binding domains, glycoproteins (has several carbohydrate attachments)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Lamin

A

fibrous proteins in type V intermediate filaments, providing structural function and transcriptional regulation IN the CELL NUCLEUS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Collagen

A

Structural support protein used for adhesion and construction of the ECM materials. One of the primary fibrous proteins of the ECM. There are 19 different types including high and low strength.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Fibronectin

A

Adhesive/ attachment proteins for adhesion and construction of the ECM materials, has unique binding sites. made of 2 similar polypeptides joinded by a disulfide bond near COOH terminal. Has several binding domains. Important in cell migration during development.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Proteoglycans

A

Cushioning protein that’s used for adhesion and construction of the ECM materials. Space filling, Acidic (bind cations and water), and resist compression thus provide cushioning.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Talin

A

transmembrane protein used to attach the actin cytoskeleton to the cell membrane by anchoring to the beta subunit of integrin. also interacts with vinculin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Vinculin

A

transmembrane protein used to attach actin cytoskeleton to the cell membrane by anchoring to the beta subunit of integrin. also interacts with paxillin and talin. binds to alpha actinin and catenin in tight junctions.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Paxilin

A

Interacts directly with vinculin and focal adhesion kinase to send signals from integrin to the nucleus. eventually up-regulating the formation of a focal adhesion plaque on the outside of the membrane.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Platelet adhesion factor (PAF)

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

PAF receptor

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Selectins

A

family of integral proteins that bind to oligosaccharides extending from other cells. a glycoprotein that interacts with other glycoproteins and other lipid associated membrane protein. calcium dependent binding. the lectin binding domain allows selectin to recognize a particular sugar moiety on the outside of a different cell.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Lectins

A

peripheral communication protein. a sugar moiety

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Focal Adhesion Kinase

A

directly interacts with paxillin to deliver a signal to the nucleus from integrin eventually up-regulating the formation of a focal adhesion plaque on the outside of the membrane.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Cadherins

A

large family of glycoproteins which join like cells together. They are calcium dependent. Tissue specific (Different types and combination expressed by different types of cells. Specific types and make-up of cadherins are present for specific tissue types) is present in junction and non-junction structures. is involved in adheren junctions which is a paired row of proteins which form a belt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Catenins

A

Part of the adheren junction belt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

IgCAMs

A

Immunoglobin like family of cell adhesion molecules are proteins that bind to one another and some other adhesion molecules. transmembrane and calcium independent binding.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Plectin

A

provides structural support to other filaments. intermediate filament. in plaque int the disk shaped adhesion proteins involved in specialization.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Nexin

A

bridge links the doublets together in flagella structure.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Actin

A

binds to actinin, vinculin and talin as part of the ECM.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Actinin

A

connects actin filaments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

BP180

A

specialized disk shaped adhesion protein. binds to plaque containing protein plectin which binds to intermediate filaments.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Claudin

A

proteins involved in tight junction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Occludin

A

proteins involved in tight junction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

ZOs

A

proteins involved in tight junction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

JAMs

A

proteins involved in tight junction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Microfilaments

A

solid filaments involved in contraction. used for cytoskeleton support, muscle contractility and binds to many accessory proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Microtubule

A

rigid tubes providing internal cellular support, made of alpha and beta subunits which have a polarity forming heterodimer (beta subunit = positive or fast growing end and alpha = negative). involved in organelle positioning within the cell (supports framework and anchors), involved in intracellular transport (movement of vesicles, mRNA and proteins), involved in cell movement (diapesesis and flagella), involved in cellular division (specialized structures that form the spindle apparatus.) made of 13 heterodimers and the beta subunit can exchange GDP for GTP to activate polymerization.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Cofilin

A

acts to destabilize f-actin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Profilin

A

accelerates the polymerization of F-actin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Tropomyosin

A

fits between actin filaments to allow for binding with myosin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Troponin

A

under control of Ca2+ binding. interference blocks contractility for relaxed or fatigued muscles.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Z-Disk

A

anchoring structures provide a structural link for actin and myosin to the z-disk. end of a sarcomere

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Titin

A

spring like structures in a sarcomere that bind to myosin and the Z-disk

35
Q

Thymosine

A

competitive inhibitor that binds to Actin-G to keep from polymerizing

36
Q

ActA

A

actin nucleating factor localized at the end of the bacterium.

37
Q

Arp2/3

A

stimulates assembley containing 7 protein subunitsand acts to nucleate actin polymerization and competes for capping protein to allow chain branching.

38
Q

WASP

A

Wiskott-Aldrich syndrome protein​ activates Arp2/3 complex stimulating assembly.

39
Q

Dynein

A

motor proteins able to transfer chemical energy to mechanical energy. Retrograde (axon end back to cell body, or cell membrane toward Golgi)interact with microtubules. inner and outer arms in flagella. can coordinate movement with microtubules to create different degrees of length.

40
Q

Kinesin

A

motor proteins able to transfer chemical energy to mechanical energy. Anterograde (cell body to axon, or sending a vesicle form golgi to membrane.) interact with microtubules

41
Q

Dynactin

A
42
Q

Kinectin

A

Fusion proteins. the heavy chain head of kinesin.

43
Q

Intermediate filament

A

structural support to other filiaments. assemble as long unit, cross bridging with plectin with desmosomes. join end to end with no polarity there. tetrameric protein. examples include keratin, nuclear lamin, and NFs. cytosolic intermediate filaments anchor desmosome.

44
Q

Ion Channel

A
45
Q

Connexon

A
46
Q

Connexin

A
47
Q

Uniporter

A

Facilitates/ controls transport of a single molecule down its concentration gradient (passive) an example of this is with glucose.

48
Q

Symporter

A

Facilitates transport of 2 different molecules, down their concentration gradients coupled with an upgradient movement, however both are going in the same direction either into or out of the cell.

49
Q

Antiporter

A

Facilitates transport of 2 different molecules 1 going up and 1 going down their concentration gradient and they are going in opposite directions.

50
Q

Hemidesmosome

A
51
Q

p120

A
52
Q

Desmosome

A
53
Q

Desmoglein

A
54
Q

Desomocolin

A
55
Q

Fluid mosaic

A

double carbon bonds have increase energy increasing kinetic energy supporting the fluid mosaic model that membrane proteins will move around the membrane.

56
Q

Plakoglobin

A
57
Q

FRAP

A
58
Q

Active transporter

A
59
Q

Hydropathy plot

A

peaks in this plot represent standing domains and the more hydrophobic on the plot we see the higher likelihood that the proteins is a transmembrane protein.

60
Q

Protofilament

A
61
Q

Aquaporin

A
62
Q

Lipid raft

A

larger structure that allows for aggregation of proteins in related function to hang together

63
Q

Signal transduction

A

receptors recognize ligands and upon ligand binding signal to inside the cell.

64
Q

Phosphotidyl-Phosphotidylserine

A
65
Q

Phosphotisylethanolamine

A
66
Q

Phpsphotidylcholine

A
67
Q

Sphingomyelin

A
68
Q

Lipsome

A
69
Q

Integral Proteins

A
70
Q

Myristilation

A

Myrstyl Anchor​ Amide link between amino and FA​

71
Q

Farnesylation

A

Farnesyl anchor Thioether linkage with cysteine

72
Q

Partition coefficient

A
73
Q

Simple Diffusion

A

high permeability compounds- Gases, small nonpolar compounds, steroids, cholesterol and caffeine
impermeable compounds- sugars, amino acids, polar macromolecules, Ions and charges molecules.

74
Q

Passive diffusion

A
75
Q

Leak Channels

A

always open to allow down gradient leaks. aquaporins are an example. 6 transmembrane domains and 4 subunits.

76
Q

Facilitated Transport

A
77
Q

Glycocalyx

A
78
Q

Basal Lamina

A

sheet like layer of proteins that provide layer of attachment for cells.

79
Q

alpha beta, - tublin

A
80
Q

MTOC

A
81
Q

Treadmilling

A
82
Q

Tropomodulin

A
83
Q

Fluorescent Microscopy

A
84
Q

GPI

A

Cell Bio (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions