Exam 3 Steroids Flashcards
Cortisol (glucocorticoid) regulates what?
carb, fat, and protein metabolism
Cortisol (glucocorticoid) maintains ___ reactivity
vascular
What helps maintain homeostasis during periods of stress?
glucocorticoid (cortisol)
Two natural glucocorticoid (cortisol) triggers?
surgery
pain
Disease resulting from excessive production of cortisol?
Cushing’s disease
Disease resulting from insufficient production of cortisol?
Addison’s disease
Taking glucocorticoids may cause a ____ disorder.
secondary
Chronic steroid use with significant stress causes what?
Secondary Adrenal Insufficiency
Rare, emergency situation that is life-threatening from chronic steroid use?
adrenal crisis
Adrenal crisis signs and symptoms?
Profuse sweating hypotension weak pulse dyspnea (labored breathing) cyanosis
Each steroid is rated as to potency as compared to a _____ equivalent dose?
hydrocortisone
What is most and least likely to cause adrenal suppression?
most = systemic steroids least = topical steroids
Corticosteroid products characterized by ____
duration of action
Amount of hydrocortisone normally secreted daily by an adult without stress?
20 mg
What if a medication exceeds dosage amount of equivalent 20 mg of hydrocortisone?
adrenal suppression
How long of steroid use before alternate therapy is sought?
1 month
What must you avoid with chronic steroid use?
aspirin and NSAIDS
Oral side effects of steroids?
candidiasis
poor wound healing
masks oral infections
xerostomia
Why use a steroid for dentistry?
reduce pain/swelling after surgery
treat inflammatory pathologies of oral mucosa
Most common route of steroid use in dentistry?
topical for 2 weeks
Dental topical drug ointment?
triamcinolone
fluocinonide
clobetasol proprionate
betamethasone
Steroid topical rinses?
dexamethasone
prednisolone
Oral steroid drugs?
methylprednisolone
prednisone
Dentists must use caution prescribing steroids to the following populations:
pregnant
pediatric
geriatric