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PHA 397 - Make-Up Therapeutics > Exam 3 - S Transmitted Diseases > Flashcards

Exam 3 - S Transmitted Diseases Flashcards

1
Q

Which STD is known as “The Great Sterilizer?”

A

Gonorrhea

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2
Q

What bacteria causes Gonorrhea?

A

Neisseria gonorrhea

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3
Q

What are the only known hosts for Gonorrhea?

A

HUMANS

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4
Q

Where does infection occur in Gonorrhea?

A

At point of contact - penis, vagina, anus, oral cavity

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5
Q

How is the bacteria Neisseria gonorrhea classified?

A
  • Gram negative

- Diplococci

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6
Q

Who is high risk for Gonorrhea?

A

MSM (men having sex with men)

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7
Q

What age group is at the highest risk of developing Gonorrhea?

A

Between the ages of 15-30

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8
Q

Who is highest risk for developing Gonorrhea?

A
  • Multiple partners

- Unprotected sex

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9
Q

What is the timeline for onset of symptoms in men for Gonorrhea?

A

Males are symptomatic in 2-8 days past exposure

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10
Q

What is the timeline for onset of symptoms in females for Gonorrhea?

A

Females are symptomatic within 10 days post exposure by are commonly asymptomatic

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11
Q

In Gonorrhea, males are symptomatic ___ to ___ days post exposure.

A

In Gonorrhea, males are symptomatic 2 to 8 days post exposure.

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12
Q

In Gonorrhea, females are symptomatic within ___ days post exposure, but are commonly asymptomatic.

A

In Gonorrhea, females are symptomatic within 10 days post exposure, but are commonly asymptomatic.

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13
Q

In males, where does Gonorrhea spread to?

A
  • Epididymis

- Prostate

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14
Q

In females, where does Gonorrhea spread to?

A
  • Cervix

- Bartholin and Skene glands

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15
Q

T/F: In untreated, Gonorrhea can disseminate (spread) to other parts of the body.

A

TRUE

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16
Q

What happens to infected tissue in Gonorrhea?

A

It becomes red, inflamed, and covered with a purulent exudate

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17
Q

T/F: Gonorrhea has vaginal/penile discharge.

A

TRUE

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18
Q

T/F: Gonorrhea does not have urinary frequency.

A

FALSE

- Gonorrhea does have urinary frequency.

19
Q

What are the following s/s commonly associated with?

  • Pelvic tenderness
  • Menorrhagia
  • Abdominal pain
A

GONORRHEA

20
Q

T/F: Arthritis can occur if Gonorrhea is left untreated and begins to disseminate.

A

TRUE

21
Q

What can occur with infants passing through the birth canal of a mother with Gonorrhea?

A

Gonococcal Ophthalmia Neonatorum

22
Q

What 5 things can be done for diagnosis of Gonorrhea?

A

1) Hx of unprotected sex, recently
2) Physical findings
3) Gram negative diplococci on gram stain
4) Enzyme immunoassay
5) DNA amplification

23
Q

Which is more reliable, enzyme immunoassay or DNA amplification?

A

DNA amplification - best test

24
Q

What does a gram stain positive for Gonorrhea look like (classified as)?

A

GRAM NEGATIVE, DIPLOCOCCI

25
Q

Which two drugs should not be used in treating Gonorrhea?

A

1) PCN

2) AZITHROMYCIN

26
Q

What drug class is used to treat Gonorrhea?

A

3rd Generation Cephalosporin

27
Q

Name the 3rd Gen cephalosporin that is used to treat Gonorrhea.

A

CEFTRIAXONE

28
Q

What route of Ceftriaxone is used to treat Gonorrhea?

A

IM or IV

29
Q

T/F: Ceftriaxone is not used PO to treat Gonorrhea.

A

TRUE

30
Q

What is the preferred treatment for Gonorrhea?

A

1) Ceftriaxone 250 mg IM, once
PLUS
2) Azithromycin 1 g PO, once

31
Q

What is the generic of Rocephin?

A

Ceftriaxone

32
Q

What is the generic of Zithromax?

A

Azithromycin

33
Q

What two drugs are used to treat Gonorrhea?

A

Ceftriaxone PLUS Azithromycin

34
Q

What is an alternative to Azithromycin in the treatment of Gonorrhea?

A

DOXYCYCLINE

35
Q

When Doxycycline is used as an alternative to Azithromycin in the treatment of Gonorrhea, what is the dosing and frequency?

A

Doxycycline 100 mg PO, Twice a day x 7 days

36
Q

What is a concern in using Ceftriaxone in the treatment of Gonorrhea?

A

Resistance - it’s the last drug we have

37
Q

What class of drugs does Azithromycin belong to?

A

MACROLIDES

38
Q

What is a concern in Doxycycline?

A

TEETH STAINING

39
Q

What is another preferred drug if Ceftriaxone is not available in treating in Gonorrhea?

A

CEFIXIME

40
Q

When Ceftriaxone not available, and Cefixime PLUS Azithromycin is used, when do you need to test of cure?

A

IN 1 WEEK

41
Q

What is the treatment if a patient is cephalosporin-allergic?

A

Azithromycin 2 g PO, once
PLUS
Test of cure in 1 week

42
Q

What constitutes a severe pcn-allergy?

A 
Hives = moderate to severe
Anaphylaxis = severe
43
Q

T/F: A cephalosporin allergy is similar to a penicillin allergy.

A

TRUE

-Both are structurally similar; if allergic to one, then likely allergic to the other

PHA 397 - Make-Up Therapeutics (15 decks)

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