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PHA 397 - Make-Up Therapeutics > Exam 1 - Urinary Incontinence (UI) > Flashcards

Exam 1 - Urinary Incontinence (UI) Flashcards

1
Q

Name the 5 types of urinary incontinence.

A

1) Stress Urinary Incontinence (SUI)
2) Urge Urinary Incontinence (UUI)
3) Overflow Incontinence (OI)
4) Mixed Incontinence
5) Functional Incontinence

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2
Q

“MUFOS” = the 5 types of UI

A 
M - Mixed incontinence
U - Urge urinary incontinence
F - Functional incontinence
O - Overflow incontinence
S - Stress urinary incontinence
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3
Q

Name the UI that is associated with urethral underactivity.

A

Stress Urinary Incontinence (SUI)

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4
Q

Name the UI that is associated with bladder overactivity.

A

Urge Urinary Incontinence (UUI)

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5
Q

Name the UI that is associated with urethral overactivity and/or bladder underactivity.

A

Overflow Incontinence

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6
Q

SUI = urethral _____

A

SUI = urethral underactivity

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7
Q

UUI = bladder ______

A

UUI = bladder overactivity

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8
Q

OI = urethral _____ and/or bladder ______

A

OI = urethral overactivity and/or bladder underactivity

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9
Q

What is the type of UI that is associated with inadequate urethral-sphincter closure under increased intro-abdominal pressure?

A

SUI

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10
Q

Name the symptoms of SUI.

A
  • Involuntary loss of small volume urine during actions that put pressure on the bladder
  • -Exercise, coughing, sneezing, and lifting
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11
Q

What are the risk factors for SUI?

A
  • Female: pg, childbirth, menopause, obesity, cognitive impairment, and aging
  • Male (UNCOMMON): prior lower urinary tract surgery of injury
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12
Q

What is the type of UI associated with bladder overactivity filling due to the involuntary detrusor contractions?

A

UUI

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13
Q

What are the two actions that can occur in UUI?

A

1) Overactive bladder

2) Detrusor overactivity

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14
Q

What is the more common diagnosis - Overactive bladder or Detrusor overactivity?

A

OVERACTIVE BLADDER

-Symptom syndrome of urgency and frequency during the day or night with or without UI

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15
Q

T/F: Large amounts of leakage tend to occur in UUI.

A

TRUE

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16
Q

T/F: OUI is a less common type of UI.

A

TRUE

17
Q

What are the symptoms of OUI?

A

Constant dribble of urine

Frequent urination of small amounts

18
Q

What happens in OUI?

A

Bladder full, but cannot empty, thus the dribbling that occurs

19
Q

What are the common causes of OUI?

A
  • Men: anatomic urethral obstruction (BPH, prostate cancer)
  • Women: urethral overactivity from cystocele formation or surgery
  • Both: neurologic dysfunction or diseases, spinal cord injury, etc.
20
Q

What is the most common combination of UI types in Mixed Incontinence?

A

Urgency and Stress UI (Bladder overactivity and urethral underactivity)

21
Q

What is the type of incontinence that is not induced by bladder or urethra abnormalities and instead by drugs or pt disease state?

A

Functional Incontinence

22
Q

Which UI type has leaking with activity?

A

SUI

23
Q

Who is in the at-risk population for urinary incontinence?

A
  • Postpartum women

- Geriatrics

24
Q

Name the medications that contribute to UI.

A
  • Diuretics, acetylcholinesterase inhibitors
  • Alpha receptor antagonists
  • Alpha receptor agonists
  • Calcium channel blockers
  • Narcotic analgesics
  • Sedative hypnotics
  • Antipsychotic agents
  • Anticholinergics
  • Antidepressants, TCAs
  • Alcohol
  • ACE inhibitors
25
Q

Name the diuretics than can contribute to UI.

A

Furosemide
Bumetonide
Thiazides (HCTZ)

26
Q

What do diuretics do to contribute to UI?

A

Polyuria, frequency, urgency (UUI)

27
Q

Name the alpha receptor antagonists that can contribute to UI.

A

Terazosin
Prazosin
Doxazosin

28
Q

What do alpha receptor antagonists do to contribute to UI?

A

Urethral relaxation (SUI in women)

29
Q

Name the alpha receptor agonists that can contribute to UI.

A

Sudoephedrine

Ephedrine

30
Q

What do alpha receptor agonists do to contribute to UI?

A

Urethral constriction (OUI)

31
Q

What UI do CCBs contribute to?

A

Urinary retention due to reduced bladder contractility (OUI)

32
Q

What UI do narcotic analgesics contribute to?

A

Urinary retention due to reduced bladder contractility (OUI and FUI)

33
Q

What is the first-line treatment for UI?

A

NON-SURGICAL, NON-PHARMACOLOGIC INTERVENTION

34
Q

What med aggravates Stress UI?

A

Alpha blockers

35
Q

Name the non-pharmacologic treatment for Stress UI.

A
  • Pelvic floor muscle training (PFMT)
  • Fluid management
  • Bladder training
  • Weight loss in obese pts
  • Female: Poise Impressa Bladder/Supports/Pessary
  • Male: Penile clamp
36
Q

What is the drug of choice for Stress UI?

A

Duloxetine (Cymbalta)

37
Q

What other drugs can be used to treat Stress UI?

A

Venlafaxine
Estrogens
Alpha agonists - Phenylephrine, Pseudoephedrine

38
Q

What is the treatment for UUI?

A
  • Oxybutynin (Ditropan)
  • OTC Oxytrol Patch
  • Tolterodine (Detrol)
  • Fesoterodine (Toviaz)
  • Trospium (Sanctura)
39
Q

What is second line treatment for UUI?

A

Mirabegron (Mybetriq)

PHA 397 - Make-Up Therapeutics (15 decks)

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