Exam 2 - Osteoporosis Flashcards
In OP, what are the most common fractures?
- Vertebrae (spine)
- Proximal femur (hip)
- Distal forearm (wrist)
___ ____ is the breakdown and assimilation of old bone in the cycle of bone growth.
BONE RESORPTION is the breakdown and assimilation of old bone in the cycle of bone growth.
T/F: Caucasian males are at more risk for development of Osteoporosis.
FALSE
-Caucasian females are at more risk for development of OP
Which drug type/class decrease bone mineral density significantly?
GLUCOCORTICOID STEROIDS
Name the two most common causes of secondary OP.
1) Vitamin d deficiency
2) Hypogonadism
What is the gold standard for risk assessment of OP?
DEX scan of hip and spine
-Dual-energy X-ray absorptiometry
What does a DEXA scan provide?
- T scores = compared to “young normal” adults of same sex
- Z scores = compared to expected norms of patients age and sex
The normal BMD T-score =
-1.0 and higher
The T-score for Osteopenia =
-1.0 to -2.5
The T-score for Osteoporosis =
-2.5 and lower
What does FRAX indicate?
10 year probability of
- Hip fracture
- Major osteoporotic fracture (vertebral, hip, forearm, proximal humerus)
When is treatment indicated with the FRAX Tool results?
> 3% of hip fracture
OR
20% risk of major OP fracture
Which calcium salt is the most potent and least expensive?
Calcium CARBONATE
How often is Zoledronic acid dosed?
ONCE YEARLY
How often is Denosumab (Prolia) dosed?
ONCE Q 6 MONTHS
