Exam 3 randoms Flashcards

Question

Lung cancer screening

Answer 1

CT scans annually for high risk patients | Not xray

Answer 2

Age 55-74 and >30 pack year smoking (1 pack yr=ppd*yrs smoking) Current smokers or quit w/in past 15 yrs Smoking cessation is only effective prevention

Answer 3

``` Fecal occult blood test (need to avoid NSAIDS, vitamin c, and iron 3 days before) Fecal immunochemical test Stool DNA Barium enemas Tumor markers (CEA) Fleg sig **Colonoscopy** ```

Answer 4

Diet (high fiber 39 g, Low fat, fruits and veg high in antiox, ca2+ rich, VitD) Smoking cess Low dose ASA in 50-59 y/o to decrease COX2-med free rad formation

Answer 5

Digital rectal exam PSA (total, velocity, free <15% Followup with transrectal ultrasound

Answer 6

5alpha reductase inh (finasteride) cause a higher grade diagnosis if get cancer Selenium and Vit E not effective

Answer 7

Pap test (mostly liquid) HPV DNA for high risk strains 21-65 every 3 years

Answer 8

less sex partners, delay onset of sex Gardasil 9 vaccine for all 9-26 Strain 16 and 18 are most harmful

Answer 9

ABCDE Asymmetry, border, color, diameter, evolving Monthly self inspection data insufficient

Answer 10

minimize UV exposure | strongest rays are 10-4 sun protection and sunscreen

Answer 11

UVB>uva SPF regards UvB At least SPF 30 q2h

Answer 12

``` must be one or more: carcinogenicity teratogenicity reproductive tox organ tox at low doses genotoxicity structure that resembles a hazardous drug NIOSH writes list ```

Answer 13

Table 1: antineoplastics Table 2: Non-antineoplastics that are hazardous Table 3: Non-antineoplastics that have reproductive effects

Answer 14

hazardous drugs needs to be in impervious plastic to keep separate from other drugs Need to be unpacked in negative pressure Unpack using PPE Gloves when transporting to storage or work areas

Answer 15

Table 3 drugs ok with other inventory Table 1 need to be in neg pressure room Need a separate refrigerator

Answer 16

Table 1 needs double PPE, in a BSC with air quality 5+ Need separate mortars, etc Prime tubing in hood Dispose in yellow bin

Answer 17

need for administering but not required from compounding

Answer 18

Separate from other family members meds wash hands before and after, use gloves, plastic medicine cups, no pill boxes Cut pills in a plastic bag Discard into plastic bag. flush toilets twice with lid down 48 hrs after chemo

Answer 19

BE CAREFUL do not admin intrathecally always but in a bag two nurse review

Answer 20

``` Myelosup Cardiotox Diarrhea/constipation Edema Dermatologic tox Naus/vom Hepatotox QT prolongation ```

Answer 21

Severity of rash correlates to response of therapy Papules erupt 2 weeks On face, scalp, upper chest, back Treat with hydrocortisone, clinda/doxy

Answer 22

Localized hyperkeratosis and painful plaques, 3-4 weeks after Avoid hot water and stress on hands/foot Treat with hydrocortisone, urea ointments, top antibiotics Exfoliate Analgesics

Answer 23

``` Hot flashes Mood changes Osteoporosis (Arom) Arthalgia Uterine/endo cancer HTN naus/vom ```

Answer 24

``` Hot flashes Sex dysfx Gynecomastia Increased chol and TGs Osteoporosis ```

Answer 25

Dress in layers non2D6 SSRI/SNRI or gabapentin Exercise NO hormone replacement

Answer 26

Exercise, acupuncture NSAIDs Vitamin D if low Switch to diff SERM or arom inh

Answer 27

Myelosupr Immune supr Rash, hand-foot syndrome, pigment changes Diarrhea

Answer 28

Loperamide Fluids Small meals with BRAT diet infection signs/symp?

Answer 29

Urea products avoid stress to feet and palms NSAIDS/APAP avoid hot/cold

Answer 30

``` Myelosupr 2ndary malignancies N/V Infertility Mucositis Pigment and rash Seizures ```

Answer 31

``` BBW teratogenic BBW VTE (use warf LMWH or ASA) myelosupr Neuropathy Constipation diarrhea Fatigue ```

Answer 32

Neuropathy (gaba, venla) | N/V/D/const

Answer 33

Differentiation syndrome | Rash/skin changes

Answer 34

Avoid PPIs, H2RAs, antacids OK to give antacid 2 hours before or after dose OK to use H2RAs 2 hrs after dose once daily

Answer 35

Serotonin syndrome or hypertensive crisis may happen if ingestion of tyramine, phenylalanine, or caffeine Alcohol can cause disulfiram-like rxn