Exam 3 - Neuro Flashcards
3 essential components of the skull
brain tissue
blood
CSF
factors that influence ICP
arterial pressure
venous pressure
intaabdominal, intrathoracic pressure
posture
temperature
blood gas (CO2 level)
normal ICP is __ to __ mmHg
5-15 mmHg
when is ICP considered elevated
sustained >20 mmHg
cerebral blood flow is what
amount of blood in mL passing through 100 G of brain tissue in 1 minute
what is the average cerebral brain flow
50 mL/100 G of brain tissue
what occurs during auto-regulation of cerebral blood flow
adjusts diameter of blood vessels
ensures consistant CBF
only effective if MAP is 70-150 mmHg
how to calculate cerebral perfusion pressure (CPP)
MAP - ICP = CPP
what is considered a normal CPP
60-100 mmHg
CPP < __ mmH is associated with ischemia and neuronal death
< 50 mmHg
there are __ stages of increased ICP
4
stage 1: increase ICP
total compensation
stage 2: increased ICP
decrease compensation
RISK for increase ICP
stage 3: increased ICP
failing compensation
clinical s/sx of increase ICP (Cushing’s Triad)
stage 4: increased ICP
herniation imminent = death
increase ICP can occur when there’s an increase of any of these 3 components
brain tissue
blood
CSF
what is cerebral edema
increase extravascular fluid in the brain
what are the 3 types of cerebral edema
vasogenic
cytotoxic
interstitial
what is the most common type of cerebral edema
vasogenic
where does vasogenic cerebral edema occur
mainly in white matter
what occurs during vasogenic cerebral edema
fluid leaks from intravascular to extravascular space
what is the cause of cytotoxic cerebral edema
secondary to destructive lesions or trauma to brain tissue
what occurs during cytotoxic cerebral edema
fluid shifts from extracellular to intracellular
what is the cause of interstitial cerebral edema
usually a result of hydrocephalus