Exam 3 - Lecture 3 (UTIs)

Question 1

most common pathogen for UTI in adults

Answer 1

E. coli (for all types)
-then Klebsiella
-then Enterococcus spp.

Question 2

pyelonephritis s/sx

Answer 2

all UTI s/sx plus:
-systemic signs like fever, chills, N/V/D
-flank pain

Question 3

for diagnosis of UTI (cystitis and pyelonephritis) you need what two criteria?

Answer 3

symptoms of specific type and urine culture

Question 4

which is faster: urine culture or urinalysis?

Answer 4

urinalysis, and gives you enough criteria to diagnose (along w symptoms)

Question 5

commonly used oral agents for UTI

Answer 5

1. nitrofurantoin (uncomplicated only)
2. fosfomycin (uncomplicated only)
3. bactrim
4. FQs: cipro, levo
5. B-lactams:
   -cephalexin
   -cefadroxil
   -cefpodoxime
   -augmentin
   -amox alone (only after susceptibility confirmed)

Question 6

threshold percent of resistance prevalence at which an agent is no longer recommended for empirical treatment

Answer 6

20%

Question 7

examples of inpatient (IV) tx

Answer 7

-amp 2g IV + gent 5mg/kg (AdjBW) IV q24h
-cefazolin 1-2g IV q8h +/- gent 5mg/kg (AdjBW) IV q24h
-ceftriaxone 1-2g IV q24h
-cefepime 1g IV q8-12h
-gent 5mg/kg (AdjBW) IV q24h

Question 8

prostatitis tx duration

Answer 8

2-4 weeks

Question 9

prostatitis tx options

Answer 9

FQs
bactrim
cephalexin or augmentin

Question 10

recurrent UTI common tx options

Answer 10

nitrofurantoin
bactrim

Question 11

definition of recurrent UTI

Answer 11

3 or more infections in 1 year
2 or more infections in 6 months