exam 3 key Flashcards

(54 cards)

1
Q

ch 13
in eukaryotes, genetic material is packaged in the nucleus. which of the following most accurately lists the components in order from increasing size (smallest to largest)?

A

nucleotide, DNA duplex, nucleosome, chromatid, chromosome

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2
Q

ch 13

during the shotgun approach to genome sequencing, the sequenced fragments originate from:

A

targeted sites scattered across the genome

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3
Q

ch 13

how can researches distinguish exons from introns?

A

the sequence of exons complements the mRNA sequence

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4
Q

ch 13

complex organisms can be characterized as having:

A

none of the answer options is correct: there is no correlation between the complexity between an organism and these characteristics

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5
Q

ch 13

the genome of viruses consists of:

A

viruses genomes can contain any of the nucleic acids listed

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6
Q

ch 13

which of the following steps comes first in sequencing?

A

breaking the DNA info

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7
Q

ch 13

once the nucleosomes have formed the nucleosomes and associated DNA are coiled to form a structure called the

A

30-nm chromatin fiber

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8
Q

ch 13
the comparison between the number of human genes and those of other animal species has led to many conclusions, including that __

A

the number of protiens expressed by the human genome is far more than the number of its genes

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9
Q

ch 14

the relatively large number of new mutations that occur in the human genome each generation is tolerable because;

A

most of our genome is non-coding DNA, so few mutations affect our protiens

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10
Q

ch 14

what is the advantage of the proofreading function of DNA polymerase?

A

DNA polymerase can repair most mutations as they occur during DNA replication

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11
Q

ch 14

in organisms with large genomes, inversions typically occur in

A

noncoding DNA

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12
Q

ch 14

insertions and deletions that occur in multiples of three nucleotides:

A

add or delete amino acids to/from the normal polypeptide

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13
Q

ch 14
a population of mosquitoes is exposed to the pesticide DDT for several generations. at the end of that time, most individuals in the population are resistant to DDT. The most likely reason is that:

A

some individuals in the original population had the mutations that lead to resistance

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14
Q

ch 14

mismatch repair, base excision repair, and nucleotide excision repair are similar in that

A

each uses an undamaged segment of DNA as a template to repair a damaged segment of DNA

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15
Q

ch 14

__ mutations are important to the evolutionary process; most cancers result from __ mutations.

A

germ-line; somatic

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16
Q

ch 14

which of the following is a large-scale mutation?

A

insertion

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17
Q

ch 15
ultraviolet light is a mutagen, but humans need some exposure to it to synthesize vitamin D. The amount of ultraviolet light that penetrates the skin depends on the skins pigmentation: more melanin means less penetration. certain mutations result in decreased melanin production. such mutations:

A

may be harmful in one environment and beneficial in another

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18
Q

ch 15

the phenotype of an individual results from an interaction between:

A

genotype and the environment

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19
Q

ch 15

most genetic variation in populations is:

A

neutral

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20
Q

ch 15

which of the following statements about restriction fragment length polymorphisms (RFLPs) is correct?

A

all of the answer options is correct

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21
Q

ch 15
when DNA with variable number tandem repeats (VNTRs) is sequenced and visualized on a gel, the resulting fragments separate according to their:

A

size

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22
Q

ch 15

harmful mutations are often eliminated in a population because:

A

the decrease survival and reproduction of the indivuduals

23
Q

ch 15
nondisjunction of X chromosomes may occur during meiosis 1 of oogenesis to form 2 types of eggs. if normal sperm fertilize these two types of egg, which of the following are possible sex chromosome complements?

24
Q

ch 15
cancer can be caused by mutations. genetic analysis of Anna Karenena’s tumor shows that the cell proliferation was triggered by a somatic mutation in the MYC gene, causing this gene to be inappropriately activated. Anna is concerned about passing this cancer on to the children she plans to have in the future. should this be a concern?

A

no, she should not worry about her children because this did not occur in a germ-line cell

25
ch 16 | Mendel's principle of independent assortment corresponds to which part of meiosis?
random alignment of the homologous on the metaphase plate during metaphase I
26
ch 16 Mendel studies seven different traits in the garden pea. What genetic term is used to describe an observable trait, such as these studied by Mendel?
phenotype
27
ch 16 | two plants are crossed, resulting in offspring with a 3:1 ratio for a particular trait. this ratio suggests that __
the parents were both heterozygous for the particular trait
28
ch 16 | segregation of the alleles corresponds to the separation of:
chromosomes
29
ch 16 which of the following would have caused Mendel to observe patterns of inheritance that supported the model of blending inheritance rather than the transmission of alleles causing discrete differences?
A, B, and C are all correct
30
ch 16 you are examining a human pedigree for a trait. you notice that an offspring can be affected even if neither parent is affected. this immediately tells you that the trait is
recessive
31
ch 16 | according to the principle of segregation, a heterozygous plant with alleles Aa will produce:
50% of gametes with the A and 50% of gametes with the a allele, on average
32
ch 16 in humans, ability to roll the tongue (R) is dominant in being unable to is dominant to being unable to roll (r). Having freckles in dominant (F) to being able to have no freckles (f). A freckled tongue-roller could have which of the following genotypes?
RRFF and RrFr only
33
ch 17 | the fact that the ratio of human male to female births is nearly 1:1 demonstrates that
X and Y chromosomes demonstrate segregation and random fertilization
34
ch 17 | in animals with sex chromosomes, males inherit their X chromosomes from their __ and transmit them to their __.
mothers/daughters
35
ch 17 red/green color blindness is a sex linked recessive trait in humans. if a carrier female (heterozygous for the trait) mated with an affected man, what would be the expected outcome(s)?
half of the daughters would be color blind
36
ch 17 | the frequency of recombination during meiosis is a function of:
the distance between genes; the farther apart the genes are, the more frequent the recombination between them
37
ch 17 | Y- linked traits are:
never inherited or transmitted by females, they are transmitted by affected fathers only to their sons
38
ch 17 the human X chromosome carries approximately 1000 genes. the Y chromosome contains only about 50 genes. how can males survive with only these 50 genes on the Y chromosome?
the Y is paired with a functional X chromosome, which has all the genes
39
ch 17 Mendel's ground breaking experiments with 7 pairs of contrasting traits in pea plants did not resolve the concept of linkage because
each of the 7 pairs of traits happened to be controlled by seven different genes, each on a distinct autosome
40
ch 17 in some cases, for X-linked traits, the genotype of a parent can be determined by the phenotype of their children. In which of the following scenarios is this true?
the phenotype of a son will determine at least one of the alleles in the mother's genotype
41
ch 17 considering an X linked dominant trait, if an unaffected woman and an affected man decided to have children, then which of the following statements is true about the possibilities for their children?
their daughters are expected to be heterozygous for the associated gene
42
ch 18 a key difference between single-gene traits such as those Mendel studied and complex traits such as human height is that:
single-gene traits are generally uninfluenced by the environment, whereas complex traits have a significant environmental componenet
43
ch 18 | inbred lines of animals, such as lab mice, are useful for studying complex traits because:
individuals are genetically identical, so differences in traits must be due to environmental differences
44
ch 18 if all variation among individuals in a population is due to differing environments, heritability is __, and the slope of the line used to measure it is __.
0; 0
45
ch 18 | a trait with high heritability will:
respond quickly to both artificial selection and narural selection
46
ch 18 ten individuals of two inbred strains of mice, A and B, are fed identical diets. All have normal blood sugar as adults. The same mice are then fed diets high in sugar. Mice from strain B develop diabetes, but mice from strain A don't. Diabetes in strain B results from:
the interaction of their diet with their genotype
47
ch 18 | heritability is defined as:
the proportion of the total variation due to genetic differences among individuals
48
ch 18 | concordance is
the percentage of cases in which both members of a pair of twins show the trait when it is known that at least one member shows it
49
ch 18 | when heritability is 100%, the variation among individuals in the population is due to;
genotype
50
bonus | why is "chain reaction" an appropriate part of the term "PCR"?
newly synthesized DNA segments serve as templates in subsequent cycles
51
bonus | how many human chromosomes could fit into a single bacterial cell?
none
52
bonus | cancer is usually due to:
a series of mutations that occur in a single lineage of somatic cells
53
bonus | studying 2 traits in fruit flies......
red segregated from brown in meiosis I, and straight segregated from curled in meiosis I
54
bonus | in humans, mitochondria (and their genomes) show:
strict maternal inheritance