Exam 3 - Adeno--Parvoviruses Flashcards
Adenoviruses
General Morphology
-non-enveloped DNA
Adenoviruses
Path
- lytic phase (epithelium)
- latent phase (lymphoid cells)
- oncogenic transformation
Adenoviruses
Epi/transmiss
-usually primary infx’n in children
Adenoviruses
clin/sx
- Pharyngoconjunctival fever (swimming pools)
- epidemic keratoconjunctivitis (bilat)
- hemorrhagic cystitis (esp boys)
Adenoviruses
dx
- viral tissue culture, e- microscopy, Ab detection
- sputum, nasopharyngeal secretions, throat swab ELISA
Adenoviruses
tx
- supportive tx
- sometimes antiviral for immunocompromised
Papillomavirus
morphology
-dsDNA
Papillomavirus
path
-binds tumor suppressor genese
Papillomavirus
Epi/transmiss
- skin-skin or membrane-membrane contact
- common/plane warts more common in children
- plantar warts more common in adults
Papillomavirus
Cutaneous Warts
clin/sx
-deep plantar: painful, raised, keratotic
-common: demarcated, hyperkeratotic, hands
plan/flat: irregular contour, smooth
Papillomavirus
Anogenital
clin/sx
- gray/fleshy, sessile/pedunculated
- shaft of the peen, posterior introitus, labia, cervix, ayn
- cervical cancer, anal cancer
Papillomavirus
dx
- acetic sol’n
- colposcopy
- Pap
- HPV DNA typing
Papillomavirus
tx
-topical salicylate, cryotherapy, lasers
Papillomavirus
prevention
- Gardasil
- against 4 types
- most imp’t: types 16 and 18
Parvovirus B19
morphology
-small non-enveloped DNA