Exam 3 Flashcards
What fiber is predominantly in cartilage
mostly collagen- which retains water for reslience
Is cartilage avascular or vascular
avascular
How is cartilage built ?
Cartilage is built and maintained by chondrocytes that live in small cavities called lacunae within the extracellular matrix.
How is cartilage maintained?
the shape of cartilage is maintained by the perichondrium-
Perichondrium
dense irregular tissue surrounding the cartilage, and also supplies nutrients and water
What are the three types of cartilage
Hyaline , Elastic, and fibrocartilage
What is the appearance of hyaline cartilage
frosted glass when freshly exposed
what is the function of saline cartilage
provides support with flexibility and resilience
what is the most abundant type of skeletal cartilage?
hyaline
what shape of chondrocytes are found in hyaline cartilage
spherical
what type of fiber is found in the matrix of hyaline cartilage
fine collagen fibers
where are the 4 skeletal locations of hyaline cartilage
- articular- covering the ends of bones at movable joints.
- costal- connects the ribs to the sternum
- respiratory- forms the skeleton of the larynx (voice box) and reinforces other respiratory passageways.
- nasal cartilage- supports the external nose
Elastic Cartilage
resembles hyaline but they contain more stretchy elastic fibers and are better able to stand up to repeated bending.
What skeletal locations can you find elastic cartilage
- external ear
* epiglottis- the flab that bend to cover the opening of the larynx each time we swallow.
Fibrocartilage
highly compressible with great tonsil strength
What is fibrocartilage composed of?
roughly parallel rows of chondrocytes alternating wth thick collagen fibers.
Where does fibrocartilage occur
in sites that are subject to both pressure and stretch, such as the bad like cartilages
what are the skeletal locations of fibrocartilage?
- menisci of the knee
- vertebral Discs
- Pubic Symphysis
How does Cartilage grow?
*Unlike bone, cartilage has a flexible matrix which can accommodate mitosis
Cartilage grows in two ways
- Appositional growth
- Interstitial growth
appositional growth
cartilage- forming cells in the surrounding perichondrium secrete new matrix against the external face of the existing cartilage tissue
interstitial growth
the lacunae bound chondrocytes divide and secrete new matrix, expanding the cartilage from within.
when does cartilage growth end?
typically ends during adolescence when the skeleton stops growing
Calcified Cartilage
during normal bone growth in youth and during old age cartilage can become calcified due to deposits of calcium salts- still does not become bone
How are bones classified
into the axial skeleton and the appendicular skeleton
axial skeleton
long axis of the body- skull, cranial, facial,hyid,vertebral column , sacrum, coccyx, thoracic cage-ribs and sternum
appendicular skeleton
bones of upper and lower limbs- girdles attaching limbs to axial skeleton- pectoral girdle(scapula, clavicle) humerus) humerus, radius, ulna, carpals,metacapals, phalanges, pelvic girdle (two hip bones) femur, fibula, patella, tarsals, metatarsals, phalanges
how many bones are in the axial skeleton
80
how many bones are in the appendicular skeleton
126
How are the bones classified based on their shape
long, short, sesamoid, flat,irregular
long bones
long longitudinal axes and wider not eh ends
ulna, radius, humorous, femur
short bones
cube like, equal length and with small, nodular, embedded in a tendon adjacent to a joint
wrist ankle bones, talus
sesamoid bone
round bone
patella
flat bone
plate like structure
ribs, scapula, some bones in the skull
irregular bones
variety of shape
vertebrae, facial bones
what are the seven functions of the skeletal system
(PMSBITH) Protection Movement Support Blood cell formation Incorporate and release of minerals as needed- calcium and phosphorous triglyceride and growth factor storage hormone production- Osteocalcin
what minerals are stored in the skeletal system
calcium and phosphorous
what hormone is produced int he skeletal system
osteocalcin
osteocalcin
important for regulating appositional growth in bones
osteocytes
maintain the bone matrix by acting as a strain/ stress sensor for the purpose of bone-remodeling
maintain
osteoblasts
actively dividing cells that create osteoid unmineralized bone matrix- primarily collagen fibers
Build
osteoclasts
WBC-Macrophage reabsorbs and breaks down extracellular matrix for the purpose of release ca into the blood
break down
osteogenic cells
actively dividing within the inside and outside linings of bone to create osteoblasts when needed.
compact bone
forms the hard-outer shell of all bones
strongest and densest form of bone in the body
contains many tiny passages for blood vessels and nerves and houses the cells that repair and maintain bones.
spongey bone
lighter and less dense than compact bone
Trabeculae
Shape of spongy bone
Osteocytes
Bone cells, surrounded by a solid intercellular matrix of mineral salts and protein fibers.
Makes up osseous tissue which makes up the compact bone
What is the matrix of osseous tissue rich in?
Calcium and phosphorus containing the mineral hydroxyapatite
Hydroxyapatite
Very hard, but brittle on its own
Osteon
microscopic cylinders Which surround tiny central canal’s.
Form during fetal development.
Lacunae
A small cavity that contains osteocytes.
Lamellae
Osteogenic cells begin to produce bone Matrix and form a ring of bone matrix Matrix this ring is known as Lamella around the blood vessels and nerves
Canaliculi
Hair like canals that connect the Lacunae to each other in the central canal
Central Haversian canals
Runs through the core of the osteon
Contains blood vessels and nerve fibers
What is the structural unit of compact bone
Osteon
Perforating Volkmans canals
Canals runs perpendicular and connects to the central haversians
Connect blood vessels and nerves of periosteum, medullary cavity, and centric canal
Epiphysis
End of the long bone which articulates with another bone
Secondary ossification center
Covered with highland cartilage called articular Cartlidge.
Filled with spongy bone
Articular cartilage
Covers the end of long bones
Proximal epiphysis
Closer to the torso
Distal epiphysis
Furthest away from the torso
Diaphysis
Shaft of the long bone
All of the diaphysis is made up of come back down.
The center is hollow chamber call the medullary cavity
Endosteum
Delicate membrane layer covering the medullary cavity surfaces
– location of the osteogenic cells
Periotenum
Outer covering of the long bone – location of iatrogenic cells and markings
Processes
Bony protrusions that provide sites for attachment of Ligaments and tendons
groove processes and openings processes
Are passage ways for blood vessels and nerves
Depression processes of the bone
Might serve as a place for articulation
Red bone marrow
Specialized connective tissue for him at a polices within the epiphysis
Yellow bone marrow
Reticular fibers network filled with lipids in the medullary cavity
Medullary cavity
Hollow chamber in the center of the diaphysis
What bone tissues are found in flat bone
Both spongy and compact
Structure of the short, irregular, and flat bones
- Then plates of spongy bone covered in compact bone.
- Plates sandwich between connective tissue membranes.
- Periosteum an interest in him.
- No shaft or a purposes.
- Red bone marrow throughout spongy bone.
- Highland cartilage covers articular surfaces.
Short bones
Are roughly cube shaped with vertical and horizontal dimensions approximately equal.
- They consist primarily of spongy bone which is covered by a thin layer of compact bone.
- Short bangs include bones of the wrist and in the ankle
Flat bones
Are thin, flattened and usually curved.
Most of the bones of the cranium are flat bones
Irregular bones
Are not in any of the above categories, are classified as a regular bones.
- They are primarily spongy bone that is covered with thin layer of compact bone.
- The vertebrae and some other bones of the skull are irregular bones
Bone development
Bone development begins at six weeks in utero and continues until age 25. After 25 but information is in the room of remodeling
Ossification
Osteogenesis
Process of bone tissue formation is used in different parts of life for different reasons.
Formation of the bony skeleton
Begins in second month of fetal development, intramembranous
Bone growth
Until Early adulthood
-endochondral
Bone remodeling and repair
Lifelong
Endochondral
What are the two types of bone ossification
Intramembranous and endochondral
Intramembranous ossification
Bone development from fibrous membrane. Used to form only flat bones like the clavicles and cranial bones
Endochondral ossification
Bone forms by replacing highland cartilage, forms most of the skeleton
What are the steps in intramembranous ossification
- Mesenchymal cells Turn into osteoblast while migrating to the ossification centers
- Osteoblast turn into osteocytes and they classify themselves in place
- Bone grows into linear expansions called specials and blood vessels will grow and branch around them to support the bone tissue
- Growth at multiple ossification centers cause enlargement and produce spongy bone, Merrill cavities and compact bone.
Where can you collect bone marrow for transplantation?
The flat bones of the pelvic girdle – ileum and also the sternum
What are the steps and endochondral ossification
- Brown color information
- Chondrocytes hypertrophy and creates cavities within the Cartlidge.
- Peritoneum bud and vision – osteoblasts and blood vessels invade the center of Cartilage in the developing bone shaft to deposit osteoblasts and osteoclasts to build spongy bone.
- Diaphysis elongation-The diaphysis in long gate using nutrients brought byParis Danielle bud and medullary cavity forms using osteoclasts in order to suppress development of bone marrow. -Secondary ossification centers form in the epiphysis of the bones
- Epiphyseal ossification
Ossification continues in the purposes and the diaphysis when complete, only two areas of highland cartilage remain at the surface of the purposes and at the epithelial plate – secondary ossification center appears in the epiphysis above the primary ossification center
What is the difference between intersexual and appositional growth
Intersexual is longitudinal gross and appositional growth increases in both thickness.
What is interstitial Growth dependent on?
- Primary ossification center.
- Epithelial plate.
- Secondary ossification center
Why must the epiphyseal plate maintain constant thickness
Rate of Cartlidge growth on one side balanced by bone replacement on the other
Why must bone remodeling occur in the epiphysis
To keep the epiphysis is the correct size otherwise your joints were at work