Exam 3 Flashcards
What does lateral and longitudinal folding cause blood islands to do?
- merge into one solid tube
* long: puts it at definitive position in Thorax
What does the Outflow tract become?
*pulmonary trunk and aorta
What do the conotruncal cushion grow out from?
*wall of primordial heart
What does the endocardial cushion grow out from?
*endocardial part of the heart
Where do the conotruncal cushion originate from?
*Neural Crest cells
What is the pathway for blood that will close?
*ostium primum
what forms from the atrioventricular canal?
*interatrium septum (fibrous skeleton of the heart)
What forms 2nd and closes off to cause misalignment of holes?
*septum seundum
What is the misaligned hole on the L side called?
*oval foramen and valve of oval foramen
What closes in fetal circulation after birth?
*ductus arteriosus, oval foramen, umbilical vein and ductus venosus, and umbilical artery
What becomes the aortic and pulmonary trunk?
- P: pulmonary channel
* A: aortic channel
What percent of babies have septal defects?
- 1% of babies (10% if include still born babies)
What percent of babies with heart problems have other developmental defects?
*30%
What are the signs and treatment of a septal defect in the membranous part of the ventricles?
- doesn’t seal up, surgery required
- baby cyanosis and sweat while suckling
- flow from L to R
How is a septal defect in the muscular part of the ventricles treated?
*seals up on its own
What are the signs of an atrial septal defect and how is it detected and treated?
- if doesn’t seal up, surgery required
- Doppler ultrasound to find hole
- shunt from R to L
- big defect causes blood to bypass pulmonary circuit (cyanotic, sweat while suckling)
- pulmonary side under more pressure (enlarged R side) if have this in adult
What are the alterations a tetralogy of fallot can cause?
- pulmonary stenosis
- overriding aorta
- interventricular septal defect
- hypertrophy
What accompanies tetralogy of fallot and how do you fix it?
- patent ductus arteriosus
* surgical fix
What is stenosis of valves?
*calcium of vales, hardening, narrow opening
What is insufficient of valves?
*doesn’t close right, blood comes back through
What is ductus arteriosus, signs and treatments?
- ductus art doesn’t close
- cyanosis sweat during suckling
- prostaglandins, surgical (can hit recurrent laryngeal nerve)
Where would hypertrophy in tetralogy of fallot occur?
- walls of RV
What part would be effected in the interventricular septal defect in tetralogy of fallot?
*membranous part
What are the muscles of the posterior abdominal wall?
*psoas, quadratus, iliacus, trans abdominis, internal and external oblique
What can a peritoneal infection do?
*travel to psoas major and go into thigh
Where is the pain felt in a psoas abscess?
*fever, pain in flank, pain walking
What is a psoas abscess caused by and how is it treated?
- staph aur
* antibiotics, surgically drained
What produces blood in the fetus?
*spleen
What stores and releases RBC?
*spleen
What is a lymphatic organ and what does that mean?
- spleen
* makes macrophages
What is the spleen derived from?
*mesoderm
What does the spleen do?
- splenic circulation (polysach. antigens recognize)
What are some reason why people don’t have a spleen?
- splenic agenesis, rupture in trauma, disease cured by removal of spleen (Hep c)
What is an overwhelming post splenectomy (OPSI) and how is it treated, and what are the signs?
- bacterial septic (blood infection)
- rec in 24-48 hours, 50-70% die
- intravenous antibiotics
- flu like symp, fever, headache, nausea
- vaccine, renew every 5 years
What gets 20% of the body’s blood supply?
*kidney
What does the kidney do and where is it located?
- removes waste
* T12-L3 vert
What is surrounded by a capsule (stretchy)?
*spleen
What is surrounded by para fat and a strong capsule of CT?
*kidney
What does the renal pyramid have in it?
*millions of nephrons
Where can you get constrictions of the ureters?
*superior part, kink over common iliac arteries, and by bladder
What is a kidney stone (renal calculi) composed of?
*oxalate, calcium, and cholesterol
Where is the pain in a kidney stone felt?
- pain when stretched
* pain in flank, groin, and lower back pain
How do you treat a kidney stone?
*lithotripsy (aim sound waves and tear them apart, epidural)
What is a stag horn calculi?
*kidney stone that remains in renal pelvis
Where do the kidneys develop?
*begin in pelvis ind evelopment
What has little anastomosis?
- segmental artery
Where is the bloodless zone?
*along lateral edge of the kidney
What is a simple renal cyst and how is it treated and detected?
- 1 or a few swollen nephrons
- needle aspirated (if pushing on something)
- ultrasound
What does the suprarenal gland not have?
*hilum
What does the suprarenal gland do?
*produce hormones
What do the hormones for the suprarenal gland do?
*regulate salt balance, glucose, androgens (esp during development)
What is the cortex and medulla derived from?
- C: mesoderm
* M: neural crest cells
Where does the medulla get sympathetic input from?
*T5-L1
What does the Medulla secrete?
*epinephrine and norepinephrine
What is a pheochromocytoma tumor and what are the signs and treatment and ways to detect it?
- adrenal constantly release EPI and norepinephrine
- rapid heart rate, forceful heart beat, high BP, shaking, tremor, sweating
- urine/blood test, imaging
- remove suprarenal gland
What can a high BP put you at risk for?
*heart attack, stroke, kidney failure
Where does the adrenal medulla pathway synapse?
- in adrenal medulla (with Chromaffin)
* has no post ganglionic fibers
What is chromaffin derived from and dump out?
- neural crest cell
* dump EPI and NPE in blood stream
Where is the superior and posterior mediastinum found?
- S: vertebrae T4 and T5
* P: T5-T12
What is in the venous angle?
*internal jugular and subclavian vein
Where are the greater/lesser/least splanchnic nerves found?
*G: T5-T10
Less: T10-T11
L: T10-T12
What do the greater/lesser/least splanchnic nerves supply input to?
*symp input to foregut and midgut
What dumps into azygous on the R side?
*posterior intercostal art
What delivers O2 arterial blood to lung tissues?
*bronchial artery
What do you have in embryo?
*2 aortas and 2 vena cavas
What predominates on the R and L side during embryo?
- vena cave predominates on R
* aorta predominates on L
What does the azygous vein supply blood to?
*superior Vena Cava
What happens in persistent L Vena Cava?
*connect common iliac to Renal on L side
What does the thoracic duct do?
*conveys most lymph of the body to the venous system
What kind of input is the Vagus nerve and what does it innervate?
- parasymp input
* abdominal structures
What is in the aortic arch?
*brachiocephalic trunk, L common carotid art, and L subclavian art
What is coarctation of aorta with collateral circulation and where does it typically occur?
- narrowing that causes obstruction to blood flow to inf part of body
- distal to ductus art and L subclavian art
What are the signs and treatment of coarctation of aorta with collateral circulation?
- babies: sweating during suckling, cyanosis
- adults: bruit, enlarged L side of heart
- balloon catherization, resection and anastomosis
What is Bruit and what can it lead to?
- swishing sound
* congestive heart failure
What are the causes of treatment of coarctation of aorta with collateral circulation?
- duct art tissue eptoptic
* not enough blood delivered during development
What is the origins of the Recurrent laryngeal nerve and what does it do?
- O: vagus nerve
* intrinsic muscle of larynx
What is the pharyngeal arch derived from and how many are there?
- 6
* derived from arch of eardrum, mandible
What happens to the 5th aortic arch?
*never develops
What is the Subclavian art derv from?
*4th arch