Exam 3 Flashcards
White adipose tissue
Energy storage, generates ATP
Brown adipose tissue
Only present early in life (never re-generated, lasts ~24h), creates heat, controlled by stress hormones
Uncoupling Agents
ex. dinitrophenol, TNT
Allow for large amounts of heat to be generated, used as weight loss medication to burn fat
Giving glucose
Must be given through an IV although it is not a long term solution, oral glucose will not work as it is turned into VFAs
Protein Function
-Tissue protein
-Keratins
-blood proteins
-enzymes
-hormones/growth factors
-immunologic functions
-Special functions ;)
Oxidative metabolism
-Gluconeogenesis, uses carbons to generate glucose
-Protein component is expensive/ not efficient (costs ATP)
-Creates large load on kidney and liver (common in older cats & dogs)
Protein digestion in monogastrics
-Low pH of the stomach denatures proteins which opens it up for proteolytic enzymes to cleave
-proteins can be absorbed as single amino acids or dipeptides in small intestines
-proteolytic enzymes in the sm intestines
exo peptadases
only cleave peptides on the end
endo peptadases
only cleave peptides on the middle
Transamination
-cleave amine group from one amino acid and transport it onto an alpha-keto acid to create a different amino acid
-how non-essential amino acids are generated
-how NPN is used as an amine donator
-in liver and IMC
What happens to left over ammonia?
- it can be utilized in the synthesis of NEAA
- absorbed into the blood and converted to urea in the kidney which is then secreted in the urine
absorption of amino acids
- absorbed in the sm intestines
-active, carrier-mediated transport
-high levels of some amino acids affect/inhibit the absorption of others
whole protein absorption
via endocytosis in neonatal ruminants to acquire passive immunity through immunoglobulins in colostrum
protein synthesis and degradation
- always happening
-growth can only occur when there is more synthesis than degradation
protein efficiency
location of phosphorus absorption
absorbed in the duodenum
What effects phosphorus absorption
- plant or animal source
- Ca:P ratio
-pH of intestines - mineral levels
- how much is already in the body
Vit D
Phosphorus excretion
mostly in urine but some can be present in the feces
Role of phosphorus in the body
- muscle
-energy
-carbohydrates
-amino acids
-fat
-nerves
What are some symptoms of phosphorus deficiency?
- weak bones (osteomalacia)
-pica (eating/ chewing non food items)
-reduction of milk and food
-weak
How are phosphorus levels measured?
-measured through the blood plasma
-usually the inverse of Ca levels
-in mg/ml
-below 4.5mg/ml = deficient
Symptoms and causes of phosphorus toxcosis