Exam 3 Flashcards
An _____ is an inherited feature that varies from individual to individual
Character
an _____ is one particular variation of a character
trait
Most human genes come in alternate versions called _____
alleles
If an organism has two non-identical versions of a gene, the one that is expressed in the organism is called the _____ allele
dominant
If an organism has two non-identical versions of a gene, the one that is not expressed in the organism is called the _____ allele
recessive
What is different between two alleles of the same gene?
The information they carry. For example, one allele might carry the information for blue eye pigment, while the other carries the information for brown eye pigment
Two alleles of the same gene ____
can be the same or can be different
When I say a flower is “purple”, what have I described?
Its phenotype
Imagine that eye color in cats is controlled by a single gene and that there are two alleles: black eyes and orange eyes. All of the offspring of a cross between a black-eyed cat and an orange-eyed cat have black eyes. This means that the allele for black eyes is _____ the allele for orange eyes
dominant to
a homozygous milk chocolate Easter bunny is crossed with a homozygous dark chocolate Easter bunny. Assuming dark chocolate is dominant over milk chocolate and the traits segregate according to Mendelian genetics, which traits will be observable in the offspring?
All dark
Assuming complete dominance, what is the expected ratio of genotypes of the offspring following the cross of two heterozygotes?
1:2:1
Assuming complete dominance, whats the expected ratio of phenotypes of the offspring following the cross of two heterozygotes?
3:1
Define Mendel’s law of independent assortment.
The inheritance of one character has no effect on the inheritance of another character
In a cross involving two autosomal traits on different chromosomes in which the parents are purebred for the opposite forms of both traits, how many of the offspring would be expected to be homozygous recessive for both traits?
1 out of 16
The following F1 cross is made: BBGg x Bbgg. Which is NOT a possible outcome in the F2 generation?
BbGG
What is Mendel’s law of independent assortment?
Independent assortment means that each pair of alleles segregates independently of the other pairs of alleles.
Mendel formulated his principles of inheritance based on ______
observations on the outcomes of breeding experiments. The underlying processes were unknown at the times
Mendel observed that pairs of alleles were separated or segregated in gametes and that they were rejoined in fertilization. We know that pairs of ____ are segregated in ____ and then are rejoined through fertilization
homologous chromosomes….meiosis
As we now understand it, the Law of Independent Assortment applies _____
to pairs of genes that are on different chromosomes, but NOT to pairs of genes that are close together on the SAME chromosome
If you are a male, the Law of Assortment indicates that your gametes contain ____
a random mix of the chromosomes you inherited from each parent
How have Mendel’s laws fared as we have learned more about cell biology and processes such as meiosis?
Our new knowledge has helped to explain some of the exceptions to Mendel’s law of inheritance
Sickle-cell disease is caused by a recessive form of hemoglobin. Two parents that do NOT have the disease give birth to a chid that does. What are the genotypes of the mother and father for the hemoglobin gene?
Both parents are heterozygous
Assuming incomplete dominance, if a homozygous red-flowered plant is crossed with a homozygous white-flowered plant, what will be the color of the offspring?
Pink
Which of the following processes generates a continuum (spectrum) of varying phenotypes?
Polygenic inheritance
Fur color in rabbits is controlled by multiple alleles. What does this mean?
Rabbits fur color is controlled by a single gene, but there are multiple versions of that gene
Which of the following statements apply to the variation in human skin color?
-Human skin color variation evolved recently in hominid evolution, once some populations of our human ancestors migrated out Africa.
- Human skin color variation likely evolved in response to differences in the intensity of sunlight around the world.
- human skin color variation is primarily determined by the type and amount of melanin pigment in the skin
Which of the following statements accurately describes melanin’s functions?
Lighter skin has less of the dark-brown eumelanin that protects cells from UV damage
Darker skin is more prevalent in high-UV areas. Dr. Nina Jablonski proposed a hypothesis to explain the selective pressure for darker skin in these environments. On what evidence did she base this hypothesis?
the melanin in darkly pigmented skin protects circulating folate from being destroyed by the UV radiation, and folate is important in human reproduction
Based on the risk factors discussed in the video, which of the following groups would be most likely to develop the bone disease rickets?
children born to parents with dark skin living far from the equator
In what way does natural selection depend on the specific environment in which an organism lives?
when the environment changes, traits that were beneficial to an organism may become harmful and vice versa.
Genes located near one another on the same chromosome are often inherited together. These are called ______
linked genes
Imagine that five hypothetical genes are arranged on a chromosome in the following order: G–H–I–J–K. Which two genes are most likely to have a crossover occur between them?
G and K
If genes are described as “sex-linked’, then they are ______
typically on the X chromosome
Recessive disorders related to genes found on the X chromosome but not on the Y chromosome are more commonly expressed in ______
Males
The inheritance pattern for red-green color blindness is different for males compared to females. Red-green color blindness is much more common in males than in females. What does this suggest about the gene for red-green color blindness?
The gene for this trait is located on the X sex chromosome
How could an embryonic stem cell be used to repair a severed spine?
Embryonic stem cells can grow into any other cell type, including a nerve cell
Guar are increasingly rare wild oxen found in Asia. How would you clone this animal?
Fusing a guar cell nucleus with an egg cell from a domestic cow that has had its nucleus removed
Mitosis occurs in _____; meiosis occurs in _____
Somatic or body cells…germ cell in the testes or ovaries
Looking through a light microscope at a cell undergoing division, you see that the condensed have lined along the midline of the cell. The homologous pairs are NOT joined in tetrads. Each chromosome takes its own place in line, independent of its homolog. You are witnessing _____
Metaphase of mitosis
Fertilization joins ___ to produce a ____
haploid gametes…diploid zygote
Duplication of the chromosomes to produce sister chromatids ______
occurs in both mitosis and meiosis
If it weren’t for ____, chromosome number would double with every generation of sexual reproduction
meiosis
Which of the following is the largest unit of DNA organization?
genome
A sugar, a phosphate, and a base are the components of a _____
nucleotide
a page is to a book as a ____ is to the genome
gene
How many polynucleotides are found in one molecule of DNA
two
Which of the following make up the backbone of a polynucleotide strand?
sugar and phosphate
What do the letters DNA stand for?
Deoxyribonucleic acid
What is different from one DNA nucleotide to the next?
The base
Which part of a nucleotide molecule in DNA encodes genetic information?
The base
What is the monomer of the DNA molecule?
Nucleotide
After DNA replication, _________
Each of the two daughter DNA molecules contains one strand from the original DNA molecule and one newly synthesized strand
How are DNA and RNA differ?
DNA contains the bases A, G, C, and T; RNA contains the bases A, G, C, and U
If DNA directs the production of RNA, what does RNA make?
RNA makes proteins
Which of the following statements is incorrect regarding DNA and RNA?
All of the above are correct
What does transcription occur in the nucleus and not in the cytoplasm in eukaryotes?
DNA cannot leave the nucleus
Which process results in the creation of mRNA?
Transcription
During transcription of a specific gene, which of the following serves as a template for the formation of RNA?
One strand of DNA
What is a gene?
All of these and more are part of the expanding definition of a gene.
What process enables several different proteins to be produced from one gene?
RNA splicing
What does “transfer RNA” actually transfer?
Amino acids
If the codon is AAA, what is the complementary anticodon?
UUU
Where does translation occur in eukaryotes?
In the cytoplasm only
The gene for the beta chain of normal human hemoglobin has the sequence CTC at the position for the seventh amino acid acid in the protein. A point mutation changing the sequence to CAC results in sickle cell hemoglobin. Use the genetic code to determine the change in the amino acid at position seven of the hemoglobin beta chain.
Glutamic acid to valine
How many nucleotides are required to code for 10 amino acids?
30
The central dogma describes how the genes in the nucleus work to produce an organism’s phenotype. Another way of putting it is that the central dogma follows the flow of information from _____
DNA to protein
DNA carries out two basic functions in cells: (1) information storage and transfer (genes can be copied and passed to offspring) and (2) the “blueprint” function (genes provides instructions for building proteins). The key process for information storage and transfer to offspring cells is _____
DNA replication
A gene is a sequence of NDA nucleotide bases that codes for a single protein. Approximately how many nucleotide bases would be required to code for a protein chain is 100 amino acids long?
300
tRNA molecules work to______
translate mRNA to produce a specific amino acid sequence
Which of the following events occurs during transcription?
A molecule of RNA is formed based on the sequence of nucleotides in DNA
Which of the following is a correct statement about mRNA?
mRNA moves from the nucleus to the cytoplasm following RNA processing
The site of translation is
ribosomes in the cell cytoplasm