Exam 2: Thalamic nuclei (given a function thats affected by a lesion know the nuclei affected, its inputs, and its outputs) Flashcards
If a lesion in the thalamus was interfering with…
somatosensory spinal inputs
(including Vestibulocortical Pathway)
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
Ventral posterolateral (VPL) nucleus
*** quiz questions about sense of fine touch from left side of his body and vestibular system***
2) Which gets inputs from:
Medial lemniscus, spinothalamic tract
3) And outputs to?
Somatosensory cortex
If a lesion in the thalamus was interfering with…
somatosensory cranial** nerve inputs and **taste
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
Ventral posteromedial (VPM) nucleus
*** quiz question about taste and sense of fine touch from face ***
2) Which gets inputs from:
Trigeminal lemniscus, trigeminothalamic tract, taste inputs
3) And outputs to?
Somatosensory and taste cortex
If a lesion in the thalamus was interfering with…
visual inputs
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
lateral geniculate (LGN) nucleus
(tip: think Lateral Light, Medial Music)
*** quiz question about visual information ***
2) Which gets inputs from:
Retina
3) And outputs to?
Primary visual cortex
If a lesion in the thalamus was interfering with…
auditory inputs
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
Medial geniculate (MGN) nucleus
(tip: think Lateral Light, Medial Music)
*** quiz question about auditory information ***
2) Which gets inputs from:
Inferior colliculus
3) And outputs to?
Primary auditory cortex
If a lesion in the thalamus was interfering with…
basal ganglia and cerebellar inputs (specific)
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
Ventral lateral (VL) nucleus
*** This is the one he wanted for the cerebellar question from the lecture quizes) ***
2) Which gets inputs from:
Internal globus pallidus, deep cerebellar nuclei, substantia nigra, pars reticulata
3) And outputs to?
Motor, premotor, and supplementary motor cortex
If a lesion in the thalamus was interfering with…
basal ganglia and cerebellar inputs (diffuse)
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
Ventral anterior (VA) nucleus
*** On exam he wants VL (specific) not VA (diffuse) for the cerebellar questions (from the lecture quizes) ***
2) Which gets inputs from:
Substantia nigra pars reticula, internal globus pallidus, deep cerebellar nuclei
3) And outputs to?
Widespread to frontal lobe, including prefrontal, premotor, motor, and supplementary motor cortex
If a lesion in the thalamus was interfering with…
Behavioral orientation toward relevant visual and other stimuli
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
Pulvinar nucleus
and Lateral posterior (LP) nucleus (functions with Pulvinar)
2) Which gets inputs from:
Superior colliculus, Tectum (extrageniculate visual pathway), other sensory inputs
3) And outputs to?
parietotemporo-occipital association
If a lesion in the thalamus was interfering with…
Limbic pathways; frontal cortex (diffuse)
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
Mediodorsal (MD) nucleus
*** Mediodorsal (MD) nucleus was a quiz question about sudden change in personality***
2) Which gets inputs from:
Amygdala, olfactory cortex, limbic basal ganglia
3) And outputs to?
Frontal cortex
If a lesion in the thalamus was interfering with…
Limbic pathways; cingulate gyrus (specific)
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
Anterior nucleus (specific)
and Lateral dorsal (LD) nucleus (diffuse)
*** Anterior nucleus was a quiz question about sudden change in personality***
2) Which gets inputs from:
Mammillary body, hippocampal formation
3) And outputs to?
Cingulate gyrus
If a lesion in the thalamus was interfering with…
Limbic pathways (Amygdala, hippocampus, limbic cortex)
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
Midline thalamic nuclei
(Contains: Paraventricular, parataenial, intranteromedial, intermediodprsal, rhomboid, reuniens aka medial ventral nuclei)
2) Which gets inputs from:
Hypothalamus, basal forebrain, amygdala, hippocampus
3) And outputs to?
Amygdala, hippocampus, limbic cortex
If a lesion in the thalamus was interfering with…
Maintaining alert consciousness
and motor relay for basal ganglia and cerebellum
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
Rostral intralaminar nuclei
(Contains: Central medial, Paracentral, and Central lateral nuclei)
and Ventral medial (VM) nucleus (may help)
2) Which gets inputs from:
Deep cerebellar nuclei, Globus palladus, brainstem ascending reticular activating system (ARAS), sensory pathways
3) And outputs to?
Cerebral cortex, striatum (caudate & putamen)
If a lesion in the thalamus was interfering with…
motor relay for basal ganglia and cerebellum
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
Caudal intralaminar nuclei
( contains: Centromedian and Parafascicular nuclei)
*** Centromedian was his answer for the quiz question asking which nucleus outputs TO** the **basal ganglia ***
2) Which gets inputs from:
Deep cerebellar nuclei, Globus palladus, brainstem ascending reticular activating system (ARAS), sensory pathways
3) And outputs to?
Striatum (caudate & putamen), cerebral cortex
If a lesion in the thalamus was interfering with…
regulated states of other thalamic nuclei
1) What nuclei is the likely location of the lesion?
2) Which gets inputs from?
3) And outputs to?
1) The lesion is most likely located in the…
Reticular nucleus
***consists of inhibitory GABAergic neurons ***
2) Which gets inputs from:
Cerebral cortex, thalamic relay and intralaminar nuclei, ARAS
3) And outputs to?
Thalamic relay and intralaminar nuclei, ARAS
