EXAM 2 STUDY SET - CH 11 Flashcards
Monosaccharides
Simplest carb.
Aldehydes / ketones w/ 2+ OH groups.
Oligosaccharides containing 2+ monosaccharides are linked by?
O-glycosidic bonds.
Glycoproteins
Carbs linked to proteins.
Membrane proteins.
What are the 3 main classes of Glycoproteins?
- Glycoproteins
- Proteoglycans
- Mucins / Mucoproteins
Proteoglycans
Attached to polysaccharide glycosaminoglycan.
Lubricants.
Mucins / Mucoproteins
Protein attached to carb by N-acetylgalactosamine.
Lubricants.
Glycosidic Bonds: N-Linked Polysaccharide
Carb attached to N in side chain of Asparagine.
Pentasaccharide core:
3 mannoses
2 N-acetylglucosamine units
Glycosidic Bonds: O-Linked Polysaccharide
Carb attached to O atom of side chain residues Serine or Threonine.
Glycosidic Bonds
link proteins and carbs.
N-linked.
O-linked.
VNTR: Variable Number of Tandem Repeats
Region of protein bb.
Rich in Serines, Threonines.
Site of glycosylation.
Where is the site of glycosylation?
VNTR
Variable Number of Tandem Repeats
Pyranose
Open chain of glucose cyclizes to when C-5 OH attacks C-1 C aldehyde.
Forms intramolecular hemiacetal.
2 Anomeric Forms:
alpha, beta.
Furanose
Open chain of fructose cyclizes to 5-membered ring when C-5 OH attacks C-2 ketone to form intramolecular hemiketal.
2 Anomeric Forms:
alpha, beta.
alpha form
C-1 OH below plane of ring
beta form
C-1 OH above plane of ring.
In furanose form of fructose the anomeric forms alpha and beta can refer to the orientation of the OH at?
C-2
Beta-D Ribofuranose
Forms part of bb of RNA.
Enantiomer of beta-L-ribose.
Maltose
Degradation product of lg oligosaccharides.
2 glucose molecules linked by alpha-1,4 linkage.
Maltose if hydrolyzed by?
maltase
Sucrose
From sugar cane / beets.
Glucose linked to fructose.
alpha - glucose
beta - fructose
Sucrose is cleaved by?
sucrase / intertase
Lactose
Disaccharide of milk.
Galactose linked to glucose by beta-1,4 linkage.
Lactose is cleaved by?
lactase
