EXAM 2 STUDY SET - CH 11

Question 1

Monosaccharides

Answer 1

Simplest carb.

Aldehydes / ketones w/ 2+ OH groups.

Question 2

Oligosaccharides containing 2+ monosaccharides are linked by?

Answer 2

O-glycosidic bonds.

Question 3

Glycoproteins

Answer 3

Carbs linked to proteins.

Membrane proteins.

Question 4

What are the 3 main classes of Glycoproteins?

Answer 4

1. Glycoproteins
2. Proteoglycans
3. Mucins / Mucoproteins

Question 5

Proteoglycans

Answer 5

Attached to polysaccharide glycosaminoglycan.

Lubricants.

Question 6

Mucins / Mucoproteins

Answer 6

Protein attached to carb by N-acetylgalactosamine.

Lubricants.

Question 7

Glycosidic Bonds: N-Linked Polysaccharide

Answer 7

Carb attached to N in side chain of Asparagine.
Pentasaccharide core:
3 mannoses
2 N-acetylglucosamine units

Question 8

Glycosidic Bonds: O-Linked Polysaccharide

Answer 8

Carb attached to O atom of side chain residues Serine or Threonine.

Question 9

Glycosidic Bonds

Answer 9

link proteins and carbs.
N-linked.
O-linked.

Question 10

VNTR: Variable Number of Tandem Repeats

Answer 10

Region of protein bb.
Rich in Serines, Threonines.
Site of glycosylation.

Question 11

Where is the site of glycosylation?

Answer 11

VNTR

Variable Number of Tandem Repeats

Question 12

Pyranose

Answer 12

Open chain of glucose cyclizes to when C-5 OH attacks C-1 C aldehyde.
Forms intramolecular hemiacetal.
2 Anomeric Forms:
alpha, beta.

Question 13

Furanose

Answer 13

Open chain of fructose cyclizes to 5-membered ring when C-5 OH attacks C-2 ketone to form intramolecular hemiketal.
2 Anomeric Forms:
alpha, beta.

Question 14

alpha form

Answer 14

C-1 OH below plane of ring

Question 15

beta form

Answer 15

C-1 OH above plane of ring.

Question 16

In furanose form of fructose the anomeric forms alpha and beta can refer to the orientation of the OH at?

Answer 16

C-2

Question 17

Beta-D Ribofuranose

Answer 17

Forms part of bb of RNA.

Enantiomer of beta-L-ribose.

Question 18

Maltose

Answer 18

Degradation product of lg oligosaccharides.

2 glucose molecules linked by alpha-1,4 linkage.

Question 19

Maltose if hydrolyzed by?

Answer 19

maltase

Question 20

Sucrose

Answer 20

From sugar cane / beets.
Glucose linked to fructose.
alpha - glucose
beta - fructose

Question 21

Sucrose is cleaved by?

Answer 21

sucrase / intertase

Question 22

Lactose

Answer 22

Disaccharide of milk.

Galactose linked to glucose by beta-1,4 linkage.

Question 23

Lactose is cleaved by?

Answer 23

lactase