Exam 2 Review Flashcards
the most common cause of increased neutrophils and decreased lymphocytes in a dairy cow would be
stress/steroid response
what are causes of a neutropenia?
- consumption with inflammatory lesion
- endotoxemia
- sepsis
- immune-mediated destruction
- decreased bone marrow production
what would be the best explanation for a lymphocytosis in a cat?
excitement (physiologic) response
excitement neutrophilia due to increase in catecholamines
what is the most sensitive indicator of stress?
lymphopenia
what change in WBC parameter would you see with hypoadrenocorticism (Addison’s disease)
lymphocytosis
in order to call a neutrophil “toxic”, what would you need to see?
vacuolated cytoplasm
what is a left shift?
increase in circulating immature neutrophils: usually involves bands. doesn’t necessarily indicate infection- reflects an inability for the BM to adequately respond with mature neutrophils
what is the reason for increased platelets in a thrombocytosis?
increased IL-6
what are causes of a thrombocytosis (increased platelets)?
- much less clinically consequential than marked thrombocytopenia
- often a “reactive” process- infection, inflammation, neoplasia, dehydration, etc
what combination of tests will provide the most accurate leukogram data from your in-clinic laboratory? (counter, person, etc)
- cell count: automated analyzer
- differential and morphology: smear evaluation
in assessing the bone marrow, what is the advantage of a core biopsy over fine needle aspirates for cytologic evaluation?
core biopsies give a better assessment of overall cellularity
a bone marrow aspirate would be appropriate for what clinical scenario?
a dog with elevated globulins and decreased WBC and platelets = doesn’t make sense and doesn’t have a cause
what type of automated hematology analyzer reports a reticulocyte count?
flow cytometer
what type of automated hematology analyzer is most commonly used in vet practice?
flow cytometer
