Exam 2 Review Flashcards
Chains of Carbon will?
Form backbones of larger organic molecules
Chains of carbon can vary in?
- length
- shape
- number of bonds
Functional groups allow…
- Other biomolecules to react with one another
- Increase the solubility of biological molecules
What are the functional groups?
- Hydroxyl
- Carbonyl
- Carboxyl
- Amino
- Phosphate
- Sulfhydryl
Define hydroxyls shape, ionization, and purpose
-Hydroxyl X–O–H
-it is NEUTRAL, meaning no charge
-molecules having O-H are alcohols
Define carbonyl’s shape, ionization, and purpose
Carbonyl shape
O
II
X – C –X
-it is NEUTRAL, no charge
-it is found at the end of carbon chains
Define carboxyl’s shape, ionization, and purpose
Carboxyl Shape
O
II
X – C – O-H
- it is an ACID, negative charge
-it loses a proton
-carbonyl and hydroxyl group combined
-O can make 1 covalent bond EXCEPTION
Define an amino groups shape, ionization, and purpose
Amino Shape
H
I
X– N :
I
H
-it is a BASE, positive charge
- 4 bonds to N, EXCEPTION
Define a phosphate groups shape, ionization, and purpose
Phosphate Group Shape
O
II
O – P – O’
O’
-it is an ACID, negative charge, the hydroxyl groups ionize at cellular pH
- the ‘ is a negative charge
-phosphates STORE ENERGY (ATP)
Define a sulfhydryl groups shape, ionization, and purpose
Sulfhydryl Shape
– S – H
- it is NEUTRAL, no charge
- form special covalent bonds in proteins
-disulfide bonds
Organic molecules contain?
C and H
Hydrocarbons are?
Rich in energy
Biomolecules are?
Organic molecules bearing functional groups
Functional groups make biomolecules?
Hydrophilic, reactive, and soluble
What are the 4 classes of biomolecules
Carbs, lipids, proteins, nucleic acids
Macromolecules are how many daltons
> 1000 daltons (1kD)
Dehydration synthesis requires?
An enzyme, and requires energy
Dehydration synthesis
BUILDS molecules
Hydrolysis requires
An enzyme, and uses energy
Hydrolysis
BREAKS molecules
What are carbs monomer and polymer
monomer- monosaccharide
polymer- polysaccharide
What is the bond between monosaccharides called?
glycosidic linkages
Carbs function as 4 things?
- energy source (monosaccharides)
- C source (monosaccarhides)
- storage (polysaccharides)
- Structural support (polysaccharides)
Name two functional groups found in monosaccharides
hydroxyl group and carbonyl group
What is the difference between alpha and beta glucose
alpha glucose- hydroxyl group UNDER
beta glucose- hydroxyl group ABOVE
remember beta= best = on top
What were the disaccharides to memorize?
sucrose = glucose + fructose
maltose = glucose + glucose
lactose = glucose + galactose
The disaccharides to memorize are all _____ of eachother?
ISOMERS
What are the storage polysaccharides?
starch (plants) and glycogen (animals in liver + muscle)
What are the structural polysaccharides?
cellulose (plant cell walls)
chitin (arthropod exoskeletons)
peptidoglycan (cell wall of bacteria)
Starch is what kind of glucose
alpha
Cellulose is…
most abundant organic compound, made from BETA glucose
Chitin is made from ____ glucose
Alpha
Peptidoglycan is made from _____ kinds of monosaccharides
Many beta
Are lipids macromolecules?
NO
Do lipids have polymers?
NO
What are the functions of a lipid?
- energy source/ C source
- storage
- structural
- cell to cell signaling (hormones)
- cell chemistry (some vitamins)
What makes a fat unsaturated
the presence of double bonds
Cis- isomers carbon is on?
Same side of the double bond
Trans- isomers carbon is on?
The opposite side of the double bond
Cis fatty acids are found in
NATURE
Triglycerides are made of
1 glycerol (alcohol) and 3 fatty acids
Phospholipids made from?
1 phosphate, 1 glycerol, 2 fatty acids (one saturated one unsaturated), and 1 additional chemical
What is a steroids structure?
4 or more rings
How many amino acids are there?
20
What are the bonds between amino acids called?
Peptide bonds
What are proteins 8 functions?
- energy source/ C source
- Storage
- structural support
- intercellular signaling
- movement
- transport
- defense
- enzymes
What is an amino acid made of?
1 amino group
1 carboxyl group
1 alpha carbon
1 H atom
1 R group (side chain)
What is basic and acidic in an amino acid?
amino group is basic
carboxyl group is acidic
What are the three groups of amino acids
polar (uncharged), charged, nonpolar
What is primary structure? What is it’s bonding?
Primary structure determines the amino acids and their order, covalent bonding between amino acids (peptide bonds)
How is the order of amino acid determined?
By the order of nucleotides in the gene for that protein
How does a polypeptide fold
in a precise way based on its primary structure
Secondary structure is? What are the two types? What type of bonding?
localized folding of the polypeptide
alpha helix and beta pleated sheet
Backbone of peptides do hydrogen bonding (amino and carboxyl group)
What does the tertiary structure involve? What holds it together?
Involves R groups
Overall 3D structure formed
Involves IMF’s
Hydrophobic forces
H-bonds
Ionic bonds
Van der Waals forces
Why do polypeptides fold into different shapes?
Folding spontaneously based on primary structure AND environmental factors
pH
Temperature
Salinity etc.
Denaturing disrupts what interactions?
WEAK INTERACTIONS ONLY (not covalent bonds)
What holds the quaternary structure together?
Hydrophobic interactions
H-bonds
Ionic Bonds
Van der Waals forces
Disulfide bridges (covalent)
What are nucleic acid monomers
nucleotides
What bonds happen in the dehydration synthesis of nucleotides
phosphodiester
Name nucleic acids five functions, what are the top TWO to memorize?
- information storage (genes) (polynucleotides)
- Useable energy (ATP) (nucleotides)
- Enzymes (polynucleotides)
- Molecular adaptor (polynucleotides)
- Cell signaling (nucleotides)
What are the three parts of a nucleotide?
pentose sugar, phosphate group, nitrogenous base
What are the pentose sugars in DNA? RNA?
DNA- deoxyribose (no O)
RNA-ribose
What are the pyrimidines?
Cytosine, Thyamine (DNA), Uracil (RNA)
What are the purines?
Adenine, Guanine
Are nitrogenous bases charged?
NO
What are the ends of DNA called?
phosphate 5’ end
pentose 3’ end
What holds the nitrogenous bases together
H-bonds