Exam 2: Renal Transplant and Donation

Question 1

An understanding of the general criteria for organ/tissue donation referrals

Answer 1

• kidney
  
  • Waiting time
  • Donor/recipient immune system compatibility
    
    • With kidney blood and HLA (6 antigen types) important
  • Prior living donor
  • Distance from donor hospital
    
    • Kidneys can go ___ hours so can go anywhere if cooled
  • Survival benefit
  • Pediatric status
• heart
  
  • Medical urgency
    
    • With heart its based on how sick they are
  • Distance from donor hospital
    
    • Also time, about 4 hours for transplant is max, so 2 hour flight away roughly
  • Pediatric status

Question 2

The Donation Process

Answer 2

• Identification and Referral
• Evaluation by the Procurement Agency
• Family Approach
• Consent and Medical/Social History
• Additional Evaluation
• Placement
• Recovery

Question 3

A knowledge of the timeline and process of organ procurement and transplantation

Answer 3

• Avg wait for kidney is 5 years
• Without O₂:
  
  • Kidney last 40 min, Liver 25 min, Heart 5-6 min
• Preservation Times:
  
  • Heart 4 – 6 hours
  • Lungs 4 – 6 hours
  • Pancreas 12 – 24 hours
  • Liver 12 – 24 hours
  • Kidneys 48 hours (iced) 72 hours (pumped)

Question 4

An understanding of the general criteria for organ/tissue donation referrals

Answer 4

• kidney
  
  • Waiting time
  • Donor/recipient immune system compatibility
    
    • With kidney blood and HLA (6 antigen types) important
  • Prior living donor
  • Distance from donor hospital
    
    • Kidneys can go 48 hours (iced) or 72 hours (pumped) so can go anywhere if cooled
  • Survival benefit
  • Pediatric status
• heart
  
  • Medical urgency
    
    • With heart its based on how sick they are
  • Distance from donor hospital
    
    • Also time, about 4 hours for transplant is max, so 2 hour flight away roughly
  • Pediatric status