Exam 2 October Flashcards
Why do cell membranes contain more unsaturated fatty acids in cool climates?
The unsaturated fatty acid tails prevent packing and maintain fluidity as membrane cools
How does cholesterol help maintain proper fluidity?
In cold temps, it prevents packing of phospholipids.
in warm temps, prevents drifting of phospholipids
Permeability is _____ correlated with fluidity.
directly (p ^ then f ^) (p down then f down)
Which molecules cross the membrane easily?
Non polar molec, O2, CO2, Steroids
Which molecules cross slowly?
H2O, small polar molec, glucose
Which molecules cross the membrane rarely?
Large polar or ionic molecules, ions, proteins, polysaccharides
What are the important functions of proteins?
- Enzymes > catalyze bio reactions
- Contractile > muscles
- Transport > both inside the cell, transport molec across cell membrane
- Structural > cytoskeleton, maintaining cell shape
What is a polypeptide?
Polymer
What is an amino acid?
monomer
What is secondary structure?
Formed when diff amino acids hydrogen bond to each other
Can different sections of a polypeptide have different secondary structure or no ss?
YES
what are the levels of structural complexity for a protein?
primary, secondary, tertiary, and quaternary
What are the five forces that cause tertiary structure?
- Hydrogen Bonds
- Ionic Bonds
- Disulfide Bridge
- Hydrophobic Effect
- Van der Waals forces
What are Van der Waals forces?
they stabilize nonpolar amino acids on the inside of proteins
What is quaternary structure?
2 or ore globular polypeptides bonded together to make a functioning protein, not all proteins have this level
What is denaturing of a protein?
Damage/unfolding caused by heat and changes in pH
What is sickle cell disease?
Change in the primary structure of hemoglobin, painful, causes blockages in arteries
What is a prion?
nervous system protein with altered secondary structure
What are some diseases that are caused by prions?
CWD, Mad Cow, Creuzfeldt-Jakob
Why is carbon a good skeleton molecule?
- needs 4 bonds: allows for greater variety of 3D shapes
- almost always makes covalent bonds (strong)
What are trans-fats?
partially hydrogenated fats, they rarely occur naturally, almost all are synthetically produced by hydrogenation
What is bad about trans fats?
Solid at room temp, stick to arteries even better than saturated fats, as long as less than .5 g/serving no requirement to label
What is a condensation reaction?
used to form all major biological molecules by bonding together momomers to make a larger polymer, always involves formation of H2O, aka dehydration reaction
What is a dehydration reaction?
Condensation reaction- When bonding glycerol to a fatty acid, the bond formed is an ester bond or ester linkage
What is a lipid?
fully or partially hydrophobic, mostly made of C and H, with some O aka fat
What is saturated fat?
NO DOUBLE BONDS, triglyceride, 14-18 carbon long tails, solid at room temp, contribute to heart problems