Exam 2: Nervous Systems Flashcards
How do actional potentials differ from hormones?
Rapid and precise signaling
How do steroids differ from action potentials?
Slow, long-lasting, systemic signals
What is a ganglion?
A collection of neurons used for interpreting, receiving, and transmitting signals
How do neuron membranes relate to circuits?
Ions flows through a channel bringing charge and changing charge on either side of the membrane
What charge does the intracellular space near a neuron membrane exhibit during hyperpolarization?
Negative
What charge does the intracellular space near a neuron membrane exhibit at resting potential?
Negative
What charge does the intracellular space near a neuron membrane exhibit during depolarization?
Positive
What are action potentials?
voltage dependent signals created by change in membrane potential
What causes depolarization of neurons?
rapid opening of voltage gated Na+ channels releases Na+ in the cell
What causes repolarization of membranes
Na+ channels are closed and K+ channels out of the cell are opened
How does axon diameter affect the conduction velocity of axon potentials?
Conduction velocity increases with increase is axon diameter
What is patch claming?
laboratory manipulation individual membrane channels in neurons to study membrane potential and electric capabilities
How does temperature affect generation of action potentials?
Generation and transmission occurs faster because voltage-gated ion channel kinetics are faster at higher temperatures
How do myelin sheath speed up action potentials?
The action potential jumps between the nodes of Ranvier
Do endotherms have larger or smaller diameter axons? Why?
Smaller because their higher body temps allow them to still conduct signals quickly
What is the first step in transmitting neurotransmitters across a synapse?
Action potential opens voltages gated Ca2+ channels
What occurs after an action potential open voltage gated Ca2+ channels in a presynaptic neuron?
Vesicle containing neurotransmitters mobilize and adhere to the presynaptic membrane
How do postsynaptic neurons receive neurotransmitters?
neurotransmitters bind to the postsynaptic receptor and triggers opening of ion channels
What are the three kinds of neurotransmitters?
Cholinergic compounds (acetylcholine)
Biogenic Amine compounds (Norepinephrine, dopamine, serotonin, GABA)
Amino Acids (glutamate)
What do ionotropic neurotransmitters do?
Induce a conformational change in postsynaptic receptor that opens ion channel
What do metabotropic neurotransmitters do?
Bind to the postsynaptic receptor and trigger release of a G-coupled protein, which causes ion channels to open
What is an excitatory post synaptic potential?
When a neurotransmitter triggers depolarization of the membrane
What is an inhibitory post synaptic potential?
when a neurotransmitter triggers polarization of the membrane
Why is it important that neurons create both inhibitory and excitatory post synaptic potentials?
Because which neurotransmitters are expresses influences likelihood of action potential being generated