Exam 2 Flashcards
What is gestational trophoblastic disease?
Hydatidiform mole, where trophoblasts develop abnormally. Placenta does not develop normally and if fetus is present, there will be fatal chromosomal defect
Medical management for hydatidiform mole
- Evacuation of trophoblastic tissue of the mole (usually by vacuum aspiration followed by curettage, then oxytocin)
- Continuous follow up to detect malignancies (choriocarcinoma may occur)
Difference between marginal placenta previa and partial placenta previa
Marginal: placenta’s border >3 cm from cervical os
Partial: placenta’s border <3 cm from cervical os, not completely covering it
What is abruptio placentae?
Separation of normally implanted placenta before fetus is born
S/S of placenta previa
Sudden onset of painless uterine bleeding in last half of pregnancy
S/S of abruptio placentae
Bleeding (may be concealed behind placenta)
Uterine tenderness
Frequent, low-intensity contractions
Abdomen/low back pain
High uterine resting tone, board like abdomen
Port wine colored amniotic fluid
Nonreassuring FHR patterns or fetal death
Signs of hypovolemic shock
Risk factors for placenta previa
Older women
Multiparty
Previous c/s
Prior uterine surgery
Asian ethnicity
Cocaine/cigarette use
Male fetus
Risk factors for abruptio placentae
Abdominal trauma
Cocaine/cigarette use
HTN
Multigravida status
Short umbilical cord
Premature rupture of membranes
Previous abruptio placentae
Symptoms of pre-eclampsia
HTN (>140/90) after 20 weeks. May be accompanied by Proteinuria
Risk factors for pre-eclampsia
Obesity
Pre-pregnancy diabetes
Treatment for preeclampsia
- Bedrest, monitor BP at home, daily weight, urinalysis, increased fetal assessments, high protein/high calorie diet
- Antihypertensive meds if BP >160/110
- 37 weeks or more: delivery
- 34-37 weeks: steroids and delay birth for 48 hrs
Meds given for severe preeclampsia
Lebatalol, Hydralazine, or Nifedipine
Magnesium sulfate
How does magnesium sulfate work?
CNS depressant, decreases amount of acetylcholine
Antidote for magnesium sulfate
Calcium gluconate
Therapeutic serum level of magnesium sulfate and toxic level
5-8 mg/dL
Toxic = >8 mg/dL
Significant adverse reactions of magnesium sulfate
CNS depression, respiratory depression, loss of DTR
Risks for mother with eclampsia
Ruptured membranes from seizure
Pulmonary edema
Heart failure
Reduced renal blood flow = Oliguria
What does HELLP stand for?
Hemolysis
Elevated liver enzymes
Low platelets
Risk factors for HELLP
Eclampsia
Chronic HTN
Diagnosis of gestational diabetes
During 1 hr GCT, if glucose > 140 mg/dL, need 3 hr
If 3 hr GTT glucose is >140 mg/dL = diabetes
Risks for fetus is mom has gestational diabetes
Congenital malformation
Small or large for gestational age
Hypoglycemia
Hypocalcemia
Hyperbilirubinemia
Respiratory distress syndrome
Classification of cardiac disease
Acquired heart disease:
- Rheumatic
- Valvular stenosis
- MI
- Cardiomyopathy
Congenital heart disease:
- Left-to-right shunt
- Right-to-left shunt
- other congenital lesions
Cause of rheumatic heart disease
Sometimes following streptococcal pharyngitis that causes scarring of heart valves (mitral valve most common)
What can rheumatic heart disease lead to?
Pulmonary HTN
Pulmonary edema
Congestive heart failure
What is valvular stenosis caused by?
Infection or blockage of the heart (can sometimes be surgically repaired)
When is a pregnant pt most at risk for an MI?
Third trimester
What is cardiomyopathy?
Rare and often fatal disorder of heart muscle structure
What are examples of a left-to-right shunt?
Atrial septal defect (hole between atria)
Ventricular septal defect (hole between ventricles)
Patent ductus arteriosus (opening between two blood vessels leaving the heart)
What are examples of right-to-left shunts?
Tetralogy of Fallot (combo of 4 heart defect, causes oxygen poor blood to flow from heart into body)
Eisenmenger syndrome (irregular blood flow in heart and lungs, causes blood vessels in lungs to become stiff and narrow)
S/S of heart disease
Dyspnea with exertion
Syncope with exertion
Hemoptysis
Paroxysmal nocturnal dyspnea
Chest pain with exertion
Which classes of heart disease are safe to get pregnant, and which aren’t?
Class I or II, high risk, but ok to get pregnant
Class III or IV, should not get pregnant (risk for MI if cardiomyopathy)