Exam 1: Week 4

Question 1

What is the medical term for low platelets?

Answer 1

thrombocytopenia

Question 2

What are three mechanisms of thrombocytopenia?

Answer 2

Consumption (getting used up), destruction, lack of production

Question 3

Reasons for platelet consumptions

and one that is usually not

Answer 3

DIC, vasculitis, envenomation, usually NOT due to blood loss

Question 4

Reasons for platelet destruction

Answer 4

Immune mediated (auto +/- RBCs, Infectious: Ehrlichia, drugs)

Question 5

Where do platelets arrive from?

Answer 5

Megakaryocytes

Question 6

Where do megakaryocytes arrive from?

location

Answer 6

bone marrow

Question 7

reasons for lack of production of platelets

Answer 7

reversible vs nonreversible stem cell injury: chemotherapeutic agents, other drugs. toxins. inflitrative diseases. estrogen toxicity.

Other cytopenias likely

A blend of mechanisms (eg destroy platlets via IMHA, develop DIC and consume remaining platelets)

Question 8

define cytopenia

Answer 8

Cytopenia means that you have low levels of red blood cells (anemia), white blood cells (leukopenia) or platelets (thrombocytopenia). Cytopenia also includes pancytopenia, which means all of your blood cell levels are low. Causes may be genetic or acquired. Depending on the cause, you may or may not need treatment.

from google

Question 9

define thrombocytosis

Answer 9

Thrombocytosis occurs when another disease or condition causes you to have a high platelet count. People who have thrombocytosis have normal platelets and a lower risk of blood clots and bleeding than people who have thrombocythemia. Thrombocytosis is more common than thrombocythemia.

Question 10

True or false: thrombocytosis, in most cases, is not of clinical concern

Answer 10

True

Question 11

What are some causes of thrombocytosis?

Answer 11

Reactive thrombocytosis (Inflammation)
Steroids (HYPERADRENOCORTICISM)
Chronic hemorrhage