Exam 1 Study--Adrenergic Drug Receptors

Question 1

Name the receptor for this drug: Epinephrine

Answer 1

Alpha at high dose, beta at low dose

Question 2

Name the receptor for this drug: Norepinephrine

Answer 2

Alpha

Question 3

Name the receptor for this drug: Dopamine

Answer 3

Alpha1 at high dose (vasoconstriction) and beta1 at low dose (cardiac stimulation); D1 (renal vasodilation), D2 (blocks NE release presynaptically)

Question 4

Name the receptor for this drug: Isoproterenol

Answer 4

Beta1 and beta2

Question 5

Name the type of drug, what type of receptor it stimualtes (if applicable), its primary use(s) and/or actions, and anything else significant about it: Fenoldopam

Answer 5

Alpha2 (moderate) and D1 (vasodilation)

Question 6

Name the receptor for this drug: Dobutamine

Answer 6

Beta1

Question 7

Name the receptor for this drug: Oxymetazoline

Answer 7

Alpha1 and alpha2

Question 8

Name the receptor for this drug: Phenylephrine

Answer 8

Alpha1

Question 9

Name the receptor for this drug: Clonidine

Answer 9

Alpha2

Question 10

Name the receptor for this drug: Metaproterenol

Answer 10

Beta2

Question 11

Name the receptor for this drug: Albuterol

Answer 11

Beta2

Question 12

Name the receptor for this drug: Terbutaline

Answer 12

Beta2

Question 13

Name the receptor for this drug: Salmeterol

Answer 13

Beta2

Question 14

Name the receptor for this drug: Formoterol

Answer 14

Beta2

Question 15

Name the receptor for this drug: Ephedrine

Answer 15

Alpha and beta

Question 16

Name the receptor for this drug: Pseudoephedrine

Answer 16

Alpha and beta

Question 17

Name the receptor for this drug: Phenoxybenzamine

Answer 17

Alpha1 and alpha2 blocker

Question 18

Name the receptor for this drug: Phentolamine

Answer 18

Alpha1 and alpha2 blocker

Question 19

Name the receptor for this drug: Prazosin

Answer 19

Alpha1 blocker

Question 20

Name the receptor for this drug: Terazosin

Answer 20

Alpha1 blocker

Question 21

Name the receptor for this drug: Doxazosin

Answer 21

Alpha1 blocker

Question 22

Name the receptor for this drug: Tamsulosin

Answer 22

Alpha1A blocker

Question 23

Name the receptor for this drug: Alfuzosin

Answer 23

Alpha1 blocker

Question 24

Name the receptor for this drug: Yohimbine

Answer 24

Alpha2 blocker

Question 25

In general, what are beta blockers used for?

Answer 25

Treating angina, arrhythmias, myocaridla infarction, heart failure, hyperthyroidism, glaucoma, and prophlylactic migraine. They lower blood pressure, but they do not cause postural hypotension due to alpha receptors being spared.

Question 26

Name the receptor for this drug: Propanolol

Answer 26

Beta1 and beta2 blocker

Question 27

Name the receptor for this drug: Timolol

Answer 27

Beta1 and beta2 blocker

Question 28

Name the receptor for this drug: Nadolol

Answer 28

Beta1 and beta2 blocker

Question 29

Why are beta1 blockers sometimes preferable to nonselective beta blockers?

Answer 29

They eliminated any unwanted bronchoconstrictor effects.

Question 30

Name the receptor for this drug: Acebutolol

Answer 30

Acebutolol is actually a partial agonist of beta1 and beta2 but is said to be an antagonist because it inhibits stimulation by the more potent endogenous catecholamines, epinephrine and norepinephrine.

Question 31

Name the receptor for this drug: Atenolol

Answer 31

Beta1 blocker

Question 32

Name the receptor for this drug: Bisoprolol

Answer 32

Beta1 blocker

Question 33

Name the receptor for this drug: Betaxolol

Answer 33

Beta1 blocker

Question 34

Name the receptor for this drug: Nebivolol

Answer 34

Beta1 blocker

Question 35

Name the receptor for this drug: Esmolol

Answer 35

Beta1 blocker

Question 36

Name the receptor for this drug: Pindolol

Answer 36

Pindolol is actually a partial agonist of beta1 and beta2 but is said to be an antagonist because it inhibits stimulation by the more potent endogenous catecholamines, epinephrine and norepinephrine.

Question 37

Name the receptor for this drug: Labetalol

Answer 37

Alpha and beta blocker

Question 38

Name the receptor for this drug: Carvedilol

Answer 38

Alpha and beta blocker

Question 39

What are the major effects mediated by alpha1 receptors?

Answer 39

Vasoconstriction, increased peripheral resistance, increased blood pressure, mydriasis, increased closure of internal sphincter of the bladder (urinary retention).

Question 40

What are the major effects mediated by alpha2 receptors?

Answer 40

Located presynaptically, they cause inhibition of NE release, inhibition of ACh release, inhibition of insulin release.

Question 41

What are the major effects mediated by beta1 receptors?

Answer 41

Tachycardia, increased lipolysis (for energy), increased myocardial contractility, increased release of renin (to increase BP).

Question 42

What are the major effects mediated by beta2 receptors?

Answer 42

Vasodilation (to get blood to muscles), decreased peripheral resistance, bronchodilation, increased muscle and liver glycogenolysis (for energy), increased release of glucagon, relaxed uterine smooth muscle.