Exam 1: General Benzos Flashcards
1
Q
Five pharmacologic effects:
A
Sedation Anxiolysis Anterograde amnesia Anticonvulsant Muscle relaxation
2
Q
Muscle relaxation produced by benzos:
A
Not adequate for surgical needs
3
Q
Safety/abuse with benzos:
A
Less potential for abuse than opioids/barbs
More safe in OD
4
Q
Structure:
A
Benzene ring fused with 7-member diazepine ring
5
Q
MoA:
A
Increase affinity of GABA for receptors
Facilitates the action of GABA
6
Q
Lipid solubility:
A
High
7
Q
Protein binding:
A
High
