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Anesthesia Pharmacology (Summer) > Exam 1: Drugs that... > Flashcards

Exam 1: Drugs that... Flashcards

1
Q

Drugs that release histamine:

A

Propofol
Morphine
Barbiturates (with rapid IV admin)
Meperidine

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2
Q

Drugs that are water soluble (in solution):

A

Midazolam
Ketamine
Dexmedetomidine
Midazolam

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3
Q

Drugs that are lipid soluble (in solution):

A

Propofol

Diazepam

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4
Q

Drugs that have active metabolites:

A 
Propofol (4-hydroxypropofol)
Ketamine (norketamine)
Midazolam (1-hydroxymidazolam)
Diazepam (desmethyldiazepam)
Morphine (morphine-6-glucuronide)
Meperidine (normeperidine)
Fentanyl (norfentanyl)
Sufentanil (desmethylsufentanil)
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5
Q

Drugs that potentiate NMBs:

A

Etomidate

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6
Q

Drugs that bronchodilate:

A

Profopol

Ketamine

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7
Q

Induction drugs in order of half-time (shortest to longest):

A

Propofol (0.5 - 1.5 hrs)
Ketamine (2 - 3 hrs)
Etomidate (3 - 5 hrs)

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8
Q

Highly protein-bound drugs:

A 
Propofol
Etomidate
Dexmedetomidine
All benzos
All barbiturates (moderately; 70-85%)
All opioids except morphine
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9
Q

Drugs that inhibit CYP450 system:

A

Dexmedetomidine

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10
Q

Drugs that induce CYP450 system:

A

Barbiturates

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11
Q

Drugs that are painful to inject:

A

Propofol
Etomidate
Diazepam
Lorazepam

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12
Q

Barbiturates in order of relative potency (least to most):

A

Thiopental: 1
Thiamylal/Surital: 1.1
Methohexital/Brevital: 2.5

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13
Q

Drugs that cause N/V:

A

Barbiturates
Etomidate/ketamine
Opioids

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14
Q

Drugs with renal metabolism:

A

Morphine

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15
Q

Drugs that undergo pulmonary uptake:

A

Meperidine
Fentanyl
Sufentanil

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Anesthesia Pharmacology (Summer) (11 decks)

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