Exam 1: Opioid Receptor Characteristics Flashcards
1
Q
Mu-1 effects:
A
Supraspinal and spinal analgesia Euphoria Miosis Bradycardia Hypothermia Urinary retention Low abuse potential
2
Q
Mu-2 effects:
A
Spinal analgesia
Depression of ventilation
Physical dependence
Constipation (marked)
3
Q
Kappa effects:
A
Supraspinal and spinal analgesia Dysphoria Sedation Miosis Diuresis Low abuse potential
4
Q
Delta effects:
A
Supraspinal, spinal analgesia Depression of ventilation Physical dependence Constipation (minimal) Urinary retention
5
Q
Mu-1 agonists:
A
Endorphins
Morphine
Synthetic opioids
6
Q
Mu-2 agonists:
A
Endorphins
Morphine
Synthetic opioids
7
Q
Kappa agonists:
A
Dynorphins
8
Q
Delta agonists:
A
Enkephalins
9
Q
Mu, kappa, and delta antagonists:
A
Naloxone
Naltrexone
Nalmefene
