Exam 1 Drugs Flashcards

1
Q

Direct-acting cholinergic agonists

A
Acetylcholine
Bethanechol
Carbachol
Methacholine
Pilocarpine
Nicotine
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2
Q

AChE inhibitors-Cholinergic agonists

A
Physostigmine
Pyridostigmine 
Edrophonium
Neostigmine
Echothiophate 
Malathion
Parathion
Tarun
Sarin
Soman
Donepezil
Rivastigmine
Galantamine
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3
Q

Reactivator of AChE

A

Pralidoxime

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4
Q

Muscarinic Antagonist - Cholinergic antagonists

A
Atropine
Scopolamine
Ipratropium 
Tiotropium
Homatropine
Tropicamide - causes mydriasis and        
                         cycloplegia 
Benzotropine 
Trihexyphenidyl
Glycopyrrolate
Tolterodine
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5
Q

Ganglion blockers - cholinergic antagonists

A

Hexamethonium

Mecamylamine

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6
Q

Neuromuscular blockers - cholinergic antagonists

Tubocurarine - nondepolarizing (ie: receptor antagonist)
Succinylcholine - depolarizing (ie: receptor agonist)

A

Tubocurarine

Succinylcholine

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7
Q

Drugs that act presynaptically- Muscarinic antagonists

A

Hemicholinium
Vesamicol
Botulinum Toxin

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8
Q

Endogenous catecholamines

A

Epinephrine
Norepinephrine
Dopamine

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9
Q

D1 Agonists

A

Fenildopam

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10
Q

Beta-agonists

A

Isoproteronol

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11
Q

Beta1-agonists - direct

A

Dobutamine

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12
Q

Beta2-agonists - direct

A

Formoterol
Albuterol
Sameterol
Terbutaline

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13
Q

Alpha1-agonists - direct

A

Phenylephrine

Causes mydriasis but not cycloplegia

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14
Q

Alpha2-agonists - direct

A

Clonidine
Methyldopa
Brimonidine

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15
Q

Indirect acting adrenergic agonists

A
Tyramine
Amphetamine
Methylphenidate
Cocaine
Atomoxetine
Modafinil
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16
Q

Mixed acting adrenergic agonists

A

Ephedrine

Pseudoephedrine

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17
Q

Alpha-antagonists

A

Phenoxibenzamine

Phentolamine

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18
Q

Alpha1-antagonists

A

Prazosin
Terazodin
Doxazosin
Tamsulosin

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19
Q

Alpha2-antagonists

A

Yohimbine

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20
Q

Beta-antagonists

A

Propranolol
Nadolol
Timolol

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21
Q

Beta1-antagonists

A

Atenolol
Metoprolol
Demolition

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22
Q

Alpha1 and Beta2-antagonists

A

Labetalol

Carvedilol

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23
Q

Partial agonists

A

Pindolol

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24
Q

Drugs used in Glaucoma

A

Pilocarpine (direct acting cholinergic agonist)

Carbachol (direct acting cholinergic agonist)

Echothiophate (Indirect acting cholinergic agonist - AChE inhibitor)

Brimonidine

Aproclinidine

Timolol (beta-antagonist)

Acetozolamide

Dorzolamide

Latanoprost

Glycerol Isosorbide

Mannitol (osmotic diuretic)

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25
Q

Histamine agonist

A

Histamine

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26
Q

Histamine antagonist - physiological

A

Epinephrine

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27
Q

Histamine antagonist - release inhibitors

A

Cromolyn

Nedocromil

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28
Q

H1 antagonists

A
Chlorpheniramine 
Cyclizine
Dimenhydrinate
Diphenhydramine 
Hydroxyzine
Meclizine
Promethazine
Fexofenadine
Loratadine
Cetirizine
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29
Q

H2 antagonists

A

Cimetidine
Ranitidine
Famotidine
Nizatidine

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30
Q

Serotonin agonists

A

Serotonin
Sumatriptan
Metoclopramide
Cisapride

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31
Q

Serotonin Antagonists - Ergot alkaloids

A
Cyproheptadine 
Ondanesterone
Ergotamine
Dihydroergotamine
Bromocriptine
Cabergoline
Ergonovine
Methylergonovine
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32
Q

Eicosinoids

A
Dinoprostone (PGE2)
Misoprostol (PGE1 derivative) 
Alprostadil (PGE1)
Prostacyclin (PGI1)
Epoprostenol (PGI2)
Latanoprost (PGF2alpha)
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33
Q

Eicosanoid antagonists

A

Zileuton
Zafirlukast
Montelukast

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34
Q

Thiazide diuretics

A

Hydrchlorothiazide
Chlorthalidone
Metolazone

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35
Q

Loop diuretic

A

Furosemide

36
Q

K+ sparing diuretics

A

Spironolactone
Eplerenone
Amiloride
Triamterene

37
Q

Carbonic Anhydrase Inhibitor

A

Acetozolamide

38
Q

Osmotic diuretic

A

Mannitol

39
Q

ADH Antagonists - Diuretic

A

Conivaptan

40
Q

ACE Inhibitors - AntiHTNs

A

Captopril
Enalapril
Lisinopril

41
Q

Renin Inhibitor - Antihypertensive

A

Aliskiren

42
Q

Angiotensin II Receptor Blockets

A

Losartan

Valsartan

43
Q

Calcium channel blockers

A
Amlodapine
Diltiazem
Nifedipine 
Verapamil
Nicardipine
44
Q

Centrally acting adrenergic drugs

A

Clonidine

Methyldopa

45
Q

Vasodilators - AntiHTNs

A

Hydralazine (pregnant women w/ eclampsia)

Minoxidil (severe ____ and alopecia androgenetica in males and females)

46
Q

Drugs for Hypertensive emergencies

A
Nitroglycerin 
Sodium nitroprusside
Hydralazine 
Esmolol
Fenoldopam
Labetolol
Nicardipine 
Diazoxide
47
Q

Drugs for Pulmonary HTN

A

Sildenafil (also used as antiangina)
Epoprostenol
Bosentan

48
Q

CHF drugs

A

ACE inhibitors/ARBs

Beta blockers

Diuretics:
Loop (furosemide)
Aldosterone Antagonists (Spironolactone, Eplerenone)
Direct Vasodilators (hydralazine, nitrates)

Inotropic agents:
Inamrinone, digoxin, dopamine, dobutamine, glucagon, milrinone)

49
Q

Class Ia Antiarrhythmics - Na+ channel blockers

A

Disopyramide
Procainamide
Quinidine

50
Q

Class II Antiarrythmics: Beta blockets

A

Propranolol
Metoprolol
Esmolol

51
Q

Class III Antiarrythmics: K+ channel blockers

A

Amiodarone
Dofetilide
Sotalol

52
Q

Class IV Antiarrythmics: Ca2+ channel blockers

Nondihydropyrimidines (have negative ionotropic and chronotropic effects)

A

Verapamil

Diltiazem

53
Q

Miscellaneous Antiarrythmics

A

Adenosine
Atropine
Magnesium
Digoxin

54
Q

Anticoagulants

A

Heparin

Warfarin

55
Q

Organic Nitrates - Antianginals

A

Nitroglycerin
Sodium Nitroprusside
Isosorbide dinitrate
Isosorbide mononitrate

56
Q

Beta blockers for Antiangina

A

Atenolol
Metoprolol
Propanolol

57
Q

Ca2+- channel blockers for antiangina

A

Amlodipine
Nifedipine
Diltiazem
Verapamil

58
Q

Anti platelet Angent

A

Aspirin

59
Q

Sodium channel Blockers for antiangina

A

Ranolazine

60
Q

Platelet aggregation inhibitors

A
Aspirin
Clopidagril
Ticlopidine
Dipyridamole
Cilostazol
Abciximab
Eprifibatide
Tirifiban
61
Q

Anticoagulants

A
HePARIN
EnoxaPARIN
DaltePARIN
TinzaPARIN
FondaPARINux
LePIRudIN
BivalirudIN
Argatroban
Dabigtran 
ApiXaban
RivaroXaban
WarfarIN
62
Q

Thrombolytics

A
Streptokinase
Urokinase
Alteplase
Reteplase
Tenecteplase
63
Q

Drugs used to treat bleeding

A

Vitamin K
Plasma fractions
Profaning dulfate
Aminocaproic acid

64
Q

Iron preparations - Anemia

A

Ferrous salts
Iron dextran
Iron sucrose
Sodium ferric gluconate complex

65
Q

Iron chelators

A

Deferoxamine

Deferasirox

66
Q

Vitamins used to treat Macrocytic anemia

A

Vit B12

Folic acid

67
Q

Hematopoietic growth factors

A
Erythropoietin 
IL-11
Darbepoetin
Sargramostim
Filgrastim
68
Q

Agents used to treat sickle cell disease

A

Hydroxyurea

69
Q

HMG-CoA Inhibitors

A
AtorvaSTATIN
SimvaSTATIN
LovaSTATIN
FluvaSTATIN
PravaSTATIN
RosuvaSTATIN
70
Q

Fibrate derivatives - Antihyperlipidemics

A

Gemfibrozil

Fenofibrate

71
Q

Anti hyperlipidemia

A

Niacin

72
Q

Bile acid binding resins

A

Cholestyramine
Colestipol
Colesevelam

73
Q

Cholesterol absorption inhibitors

A

Ezetimibe

74
Q

w-3 fatty acids - reduce TG biosynthesis and increase fatty acid oxidation in the liver

A

EPA
DHA
Lovaza

75
Q

Adrenergic agonists for respiration

A
Albuterol 
Pirbuterol
Terbutaline
Salmeterol
Formoterol
76
Q

Methylxanthines

A

Theophylline

Aminophylline

77
Q

Muscarinic antagonists for respiration

A

Ipratropium

Tiotropium

78
Q

Histamine release inhibitors for respiration

A

Cromolyn

Nedocromil

79
Q

Corticosteroids

A
Beclomethasone
Dexamethasone
Fluticasone
Budesonide
Flunisolide
Prednisolone
80
Q

Leukotriene antagonists

A

Zileuton
Zafirlukast
Montelukast

81
Q

Antibodies for respiration

A

Omalizumab

82
Q

Opioids for respiration

A

Codeine

Dextrometorphan

83
Q

Mucolytic agents for respiration

A

N-acetylcysteine

84
Q

H1 antagonists for respiration

A
Diphenhydramine 
Chlorpheniramine 
Loratadine
Fexofenadine
Cetirizine
85
Q

Cyproheptadine

A

useful in serotonin syndrome

86
Q

Ondansetrone

A

Anti-emetic
Serotonin antagonist
Ergot alkaloid

Acts on a ligand gated ion channel receptor