ANTIEPILEPTICS Flashcards by Shikeba Mehmood | Brainscape

Q

Phenytoin

A

Blocks voltage gated Na+ channels —> dec glutamate release

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Q

Carbamazepine

A

Blocks voltage gated Na+ channels —> dec glutamate release

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Q

Lamotrigine

A

Blocks voltage gated Na+ channels —> dec glutamate release

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Q

Zonisamide

A

Blocks voltage gated Na+ channels —> dec glutamate release

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Q

Oxcarbazine

A

Blocks voltage gated Na+ channels —> dec glutamate release

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Q

Ethosuximide, valproate

A

Blocks voltage gated Ca2+ channels

Absence seizures —> involve neuronal activity b/w thalamus and cortex mediated by T type Ca2+ channels

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