Exam 1 - Ch. 13 Flashcards
In cancer development, Infiltrating immune cells cause
chronic inflammation, creating a permissive tumor-progressing environment
Conditions that ↑ susceptibility to cancer include
Prenatal and early life exposure
Parental exposures before conception
Nutrition and DES exposure
Gene and environment interactions
Developmental plasticity
Degree to which development is
contingent on its environment
Reducing cancer risk must start early in life by
Avoid sun exposure during peak hours, cover the skin, increase physical exercise, and avoid high-risk sexual practices.
Cigarette smoking
is carcinogenic and the most important risk factor
for cancer
Secondhand smoke
Environmental tobacco smoke (ETS) ↑ the risk for lung cancer
Nutrigenomics
the study of nutrition on the phenotypic
variability of individuals, based on genomic differences
Xenobiotic chemicals
Toxic, mutagenic, and carcinogenic chemicals in food
Glutathione-S-transferases (GSTs)
Enzyme housekeepers that metabolize environmental carcinogens and reactive oxygen species (ROS)
After a cancer diagnosis, physical activity..
is associated with improved cancer-specific and overall survival with early-stage breast, prostate, and colorectal cancers
Air pollution
Is linked to lung cancer
Outdoor
Indoor considered worse than outdoor
Radiations that can cause cancer
Ionizing
Ultraviolet
Electromagnetic
Ch. 13 Reverse
chronic inflammation, creating a permissive tumor-progressing environment
In cancer development, Infiltrating immune cells cause
Ch. 13 Reverse
Prenatal and early life exposure
Parental exposures before conception
Nutrition and DES exposure
Gene and environment interactions
Conditions that ↑ susceptibility to cancer include
Ch. 13 Reverse
Degree to which development is
contingent on its environment
Developmental plasticity