Exam 1 Flashcards
All chromosomes apart from the sex chromosomes
Autosomes
A chromosome that is represented differently in the two different sexes
Sex chromosomes
Female homozygous for the recessive allele or males hemizygous for it display the recessive phenotype
X-linked recessive
heterozygous females and males hemizygous for the dominant allele express the dominant phenotype
X-linked dominant
Transcription factor needed for male-specific gene expression
SRY
PAR1 and PAR2, exist between the X and Y chromosomes
Pseudoautosomal regions
One of two X chromosomes in each female somatic cell is randomly inactivated
Random X inactivation hypothesis, Lyon hypothesis
Intermating group of individuals
Population
The relative frequency of a gene allele in a population
Gene Frequency
The relative frequency of a genotypic in a population
Genotypic Frequency
Relative frequency of a phenotype in a population
Phenotypic Frequency
The collection of alleles found in the members of a population
Gene pool
Describes the relationship of allele and genotype frequencies in populations
Hardy-Weinberg Law
In an “ideal” population that is infinitely large with random mating and not subject to any evolutionary forces allele and genotypic frequencies remain constant from one generation to the next
Hardy-Weinberg Equilibrium
Factor (gene) capable of masking the presence of a second factor (gene) in the expression of a phenotype
Dominant
Factor (gene) being masked by the dominant factor (gene)
Recessive
Heterozygote cannot be distinguished from the homozygous dominant
Complete Dominance
Heterozygote more closely resembles the homozygous dominant
Partial Dominance
The heterozygote is exactly halfway between the homozygous dominant and the homozygous recessive
No Dominance
The heterozygote exceeds the range established by the homozygous genotypes
Overdominance
Both alleles are expressed in separate and distinguishable manner
Codominance
The heterozygote exceeds the range established by the homozygous genotypes but can only be passed on from one direction
Example: Callipyge Sheep
Polar Overdominance
The proportion of individuals with a single gene mutation do not have an observable phenotype
Penetrance (incomplete)
Individuals with the same genotype exhibit varying degree in which the trait is expressed
Expressivity
Interaction among genes at different loci such that the expression of genes at one locus depends on the alleles present at one or more other loci. (masking-recessive)
Epistasis
Expression is absolutely limited to one sex
Sex-limited
The sex influences expression but is not limited to one sex
Sex-Influenced