Exam 1 Flashcards

1
Q

In eukaryotic cells, DNA is wrapped around proteins called

A

Histones

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2
Q

Define genome

A

The complete genetic information of a species.

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3
Q

What bacterial structure is the arrow pointing to?

A

Plasmid

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4
Q

Homologous chromosomes

A

Have same gene and different alleles

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5
Q

Model organisms and two characteristics

A

Fruit flies and e.coli
Easy to grow and short life cycle

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6
Q

Building blocks of polypeptides

A

Amino acids

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7
Q

What does a nucleotide consist of

A

Phosphate group, nucleotide base and deoxyribose

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8
Q

How does the structure of DNA give its properties

A
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9
Q

The central dogma and its extensions

A
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10
Q

Do genomes tend to get bigger or smaller over time?

A

They tend to get bigger over time because of mechanisms that add DNA sequences to genomes

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11
Q

Bacterial vs Eukaryotic genome

A
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12
Q

Chromosome structure

A
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13
Q

Redundancy

A

To have many versions of the same information. Examples: gene families, 2 copies of genes (ressesive alleles) , multiple codons for same amino acids

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14
Q

Robustness

A

Alternate systems/routes can be utilized to lead to same outcome. Example: molecular pathway

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15
Q

Sources of genome variation

A

RFLPs, Restriction duties, CNVs, and mutations

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16
Q

DNA replication in bacteria vs. eukaryotes

A

Replication in bacteria only consists of one origin
Replication in eukaryotes consists of multiple origins

17
Q

The process of DNA replication, including all the enzymes involved

A
  1. Helicase
  2. Primase
  3. DNA polymerase
  4. Ligase
  5. SSB proteins
  6. Topoisomerase
18
Q

Helicase

A

Unwinds and Esperanto’s the double strands. Forms the replication fork by breaking hydrogen bonds between nucleotide pairs in DNA.

19
Q

Primase

A

The polymerase doesn’t know where to start so the Primase has to make a primer to tell polymerase where to work. (The primer is RNA)

20
Q

DNA Polymerase

A

Replicates DNA to build a new strand of DNA

21
Q

Ligase

A

Bonds the DNA fragments together